Rv0223c - aldehyde dehydrogenase

Expression: Most Significant Conditions for Rv0223c

Protein Domains

Gene Information
Locus	Rv0223c
Symbol
Gene Name	aldehyde dehydrogenase
Location	266301 - 267764 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1464 bp Protein:488 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	36938
Related Genes	MAP3662c MAV_4946 Mkms_0227 Mmcs_0217 MSMEG_0309 MT0233 MUL_1122 Mvan_0240 nfa54770
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0223c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0223c Transcript 1
MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAADVDAAVAAARAAFD
NGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPPTIIETMHWMGSMGAMNYF
AGAADKVTWTETRTGSYGQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLK
PAAETPLTANALAEVFAEVGLPEGVLSVVPGGIETGQALTSNPDIDMFTFTGSSAVGREV
GRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQGCVNQTRILAPRSR
YDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGYIAKGIEEGARLVCGGGRP
EGLDNGFFIQPTVFADVDNKMTIAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGSVW
TTDVPKGIKISQQIRTGTYGINWYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLL
PMGYTVA*

Genomic Sequence

>Rv0223c
ATGTCTGACAGTGCCACGGAATACGACAAGCTTTTCATCGGCGGCAAGTGGACCAAACCG
TCGACCTCCGATGTTATCGAGGTACGCTGCCCAGCCACTGGGGAATATGTCGGCAAGGTG
CCGATGGCGGCCGCCGCCGACGTCGACGCCGCGGTCGCCGCAGCACGTGCGGCGTTCGAC
AACGGCCCCTGGCCCTCGACCCCGCCGCACGAGCGTGCGGCGGTGATCGCTGCGGCGGTC
AAGATGCTGGCTGAGCGCAAGGACCTGTTCACCAAGCTGCTCGCAGCCGAAACCGGCCAG
CCGCCGACCATCATCGAGACGATGCACTGGATGGGTTCGATGGGGGCGATGAACTACTTT
GCCGGTGCAGCGGACAAGGTCACCTGGACCGAAACCCGCACCGGCTCCTATGGACAGAGC
ATTGTCAGCCGTGAGCCGGTCGGTGTGGTGGGCGCGATCGTGGCCTGGAACGTCCCGCTG
TTTCTGGCCGTCAACAAGATTGCGCCGGCGCTGCTGGCCGGCTGCACCATCGTGCTCAAG
CCCGCCGCCGAAACACCGCTGACCGCAAACGCTTTGGCGGAGGTGTTCGCCGAGGTGGGC
CTGCCCGAGGGGGTGTTGTCGGTAGTGCCGGGAGGGATTGAGACCGGTCAGGCGCTGACG
TCTAACCCGGACATCGACATGTTTACCTTCACCGGCAGCTCGGCCGTCGGCCGAGAGGTC
GGCAGGCGTGCCGCTGAGATGCTCAAGCCGTGCACCTTAGAACTCGGCGGCAAGTCGGCG
GCCATCATTCTCGAGGACGTCGACCTGGCCGCAGCTATTCCGATGATGGTGTTCTCCGGC
GTCATGAACGCCGGACAGGGCTGCGTCAACCAGACCCGCATTCTGGCTCCGCGCTCCCGG
TACGACGAAATCGTGGCTGCGGTAACTAATTTCGTAACGGCTCTCCCGGTGGGCCCGCCG
TCGGACCCGGCAGCTCAGATCGGGCCGCTGATCTCGGAGAAGCAGCGGACTCGCGTTGAA
GGCTACATCGCCAAGGGCATCGAGGAGGGCGCTCGGTTGGTGTGCGGCGGCGGCCGTCCC
GAGGGCTTGGACAACGGCTTCTTTATCCAACCCACCGTATTCGCCGATGTCGACAACAAG
ATGACCATCGCACAGGAGGAGATCTTCGGGCCGGTGCTGGCCATCATTCCTTATGACACC
GAGGAGGACGCGATCGCGATCGCCAACGATTCAGTGTATGGGCTGGCGGGCAGCGTGTGG
ACCACCGACGTGCCCAAAGGCATCAAGATCTCGCAGCAGATCCGCACCGGGACATACGGA
ATCAACTGGTACGCCTTCGATCCCGGCTCACCCTTCGGCGGCTACAAGAACTCCGGAATC
GGCCGCGAGAACGGGCCCGAGGGTGTCGAACACTTCACCCAGCAAAAGAGTGTCCTGCTG
CCGATGGGCTACACCGTCGCGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008