Rv0486 - mannosyltransferase

Expression: Most Significant Conditions for Rv0486

Protein Domains

Gene Information
Locus	Rv0486
Symbol
Gene Name	mannosyltransferase
Location	575348 - 576790 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1443 bp Protein:481 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33843
Related Genes	Acel_0073 BL0826 CE0422 cg0481 DIP0388 jk1914 MAP3979 MAV_4664 Mkms_0670 ML2443 Mmcs_0657 MSMEG_0933 MT0504 MUL_4556 Mvan_0827 nfa51920 SAV4006
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0486
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0486 Transcript 1
MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALLAVHTSPLAQP
GTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPVVRVAPGVLVRNVVAGPFEGL
DKYDLPTQLCAFAAGVLRAEAVHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVHTAHTL
AAVKNAALADGDGPEPPLRTVGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHP
GVDLDVFRPGDRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPGVRIIVAGG
PSGSGLASPDGLVRLADELGISARVTFLPPQSHTDLATLFRAADLVAVPSYSESFGLVAV
EAQACGTPVVAAAVGGLPVAVRDGITGTLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRA
AARHAATFSWENTTDALLASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA
*

Genomic Sequence

>Rv0486
ATGGCAGGTGTGCGGCACGATGACGGTTCAGGGTTGATCGCCCAGCGCCGTCCGGTCCGC
GGCGAGGGTGCCACCCGCTCGCGCGGCCCATCCGGGCCATCCAATCGGAATGTTTCGGCA
GCAGACGACCCGCGCCGGGTTGCGCTGCTGGCGGTGCACACCTCACCGCTGGCACAGCCG
GGCACCGGTGACGCCGGCGGCATGAACGTCTACATGCTGCAAAGTGCGCTGCACCTGGCC
CGTCGGGGCATCGAGGTGGAGATCTTCACCCGGGCCACCGCATCGGCAGATCCACCGGTG
GTGCGGGTGGCACCCGGGGTGCTGGTGCGCAACGTGGTGGCGGGGCCCTTCGAGGGTTTG
GACAAGTACGACCTGCCCACCCAGCTTTGTGCGTTCGCCGCCGGGGTGCTGCGCGCCGAG
GCGGTCCACGAACCGGGTTACTACGACATCGTGCACTCGCACTACTGGCTGTCGGGTCAG
GTCGGCTGGCTGGCGCGCGACCGCTGGGCGGTGCCGTTGGTGCACACCGCACACACGCTG
GCCGCCGTGAAGAACGCGGCACTGGCCGACGGCGACGGACCCGAGCCGCCGCTGCGTACG
GTCGGGGAGCAGCAGGTCGTCGACGAGGCGGATCGGTTGATCGTCAACACCGACGATGAA
GCCAGGCAAGTGATTTCGCTTCATGGTGCCGATCCGGCACGAATCGACGTGGTCCATCCC
GGTGTCGATCTGGACGTGTTCCGCCCGGGTGATCGGCGCGCGGCCCGGGCCGCGCTAGGA
CTACCAGTTGACGAGCGCGTGGTGGCCTTCGTCGGACGCATCCAGCCGCTGAAGGCACCC
GACATTGTGCTGCGTGCGGCCGCCAAGTTGCCCGGGGTGCGCATCATCGTGGCCGGCGGA
CCGTCGGGCAGCGGTCTGGCTTCACCGGACGGACTGGTCCGGCTCGCCGACGAACTGGGC
ATCTCTGCACGGGTGACGTTTCTGCCGCCGCAGTCCCACACGGATCTGGCCACCTTGTTT
CGGGCGGCGGACCTGGTTGCGGTGCCGAGCTACTCCGAGTCGTTCGGCCTGGTTGCTGTG
GAGGCCCAAGCGTGCGGCACACCGGTGGTGGCCGCGGCGGTGGGCGGGCTGCCCGTCGCG
GTGCGCGACGGGATCACCGGCACCCTGGTGTCCGGGCACGAGGTCGGTCAGTGGGCCGAC
GCCATCGATCACCTGCTGCGGTTGTGTGCCGGGCCACGGGGACGGGTGATGAGCCGGGCG
GCGGCACGGCACGCCGCCACGTTCTCGTGGGAGAACACCACCGACGCGCTGTTGGCCAGT
TATCGGCGTGCGATCGGCGAGTACAACGCCGAGCGCCAGCGCCGGGGCGGCGAGGTGATA
TCGGACCTGGTAGCGGTGGGCAAGCCCCGCCACTGGACGCCGCGTCGCGGGGTGGGCGCG
TGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Term	TBRXN:IACGAMS 1D-myo-inositol 2-Acetamido-2-deoxy-D-glucopyranoside synthesis - ISS	active	njamshidi	2012-10-05
	See PMID: 12754249, Cole et al text: Tuberculosis and Tubercle Bacillus GL. Newton, T. Koledin et al. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). J. Bacteriol. 2003
Term	TBRXN:IACGAMS 1D-myo-inositol 2-Acetamido-2-deoxy-D-glucopyranoside synthesis - IDA	active	njamshidi	2012-10-05
	See PMID: 12754249, Cole et al text: Tuberculosis and Tubercle Bacillus GL. Newton, T. Koledin et al. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). J. Bacteriol. 2003
Interaction	Regulatory Rv0485	active	gaat3s	2012-10-05
	GL. Newton, N. Buchmeier et al. Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria. Microbiol. Mol. Biol. Rev. 2008
Interaction	Regulatory Rv0485	active	shahanup86	2012-10-05
	GL. Newton, N. Buchmeier et al. Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria. Microbiol. Mol. Biol. Rev. 2008
Other	EC:	active	jjmcfadden	2012-03-05
	Inferred from direct assay GL. Newton, T. Koledin et al. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). J. Bacteriol. 2003