Rv0587 - hypothetical membrane protein yrbE2A

Expression: Most Significant Conditions for Rv0587

Protein Domains

Gene Information
Locus	Rv0587
Symbol	yrbE2A
Gene Name	hypothetical membrane protein yrbE2A
Location	685129 - 685926 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:798 bp Protein:266 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	25485
Related Genes	MAP4082 MAV_4553 MT0616
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0587
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0587 Transcript 1
MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLP
TLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICA
DLGARTIREEIDAMEVLGIDPIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQ
HVSAGAYVGTLTLVTGLPEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETL
VLCVIALFATNVVLTTIGVRFGTGH*

Genomic Sequence

>Rv0587
ATGACCACCCACGCCGTGATCATCACCTATCTCCGCGACCAGACGCAGCCCGCCGTCGAT
GCGATCGGCGGGTTCTACCGGACATGCGTACTGACTGGCAAGGCGCTGGTTCGGCGGCCC
TTCCATTGGCGTGAGGCGATCGAGCAGGGCTGGTTCATTACCAGCGTCTCGTTGCTGCCA
ACCCTGGCGGTGTCGATTCCGTTGACCGTGTTGATCATCTTCACGCTCAATATCCTGCTG
GCCGAGTTCGGCGCCGCCGACATCTCCGGCGCCGGCGCGGCGCTAGGCGCGGTCACCCAG
CTGGGCCCGCTGACCACCGTGTTGGTGATTGCCGGCGCTGGAGCCACAGCGATCTGCGCC
GACCTGGGTGCCCGCACCATCCGGGAAGAGATCGATGCGATGGAGGTGCTGGGCATCGAC
CCCATCCACCGGCTGGTGGTGCCTCGGGTCGTTGCCGCGACCATCGTCGCCGCACTGCTT
AACGGCGCGGTGATAACCATTGGCCTGGTTGGTGGTTTCGTCTTCAGTGTCTTCATCCAA
CACGTCTCGGCCGGCGCCTACGTGGGCACGCTCACCTTGGTCACCGGTCTACCCGAGGTG
ATCATCTCGGTGGTCAAGTCGGCGACGTTCGGCCTGATCGCTGGCCTAGTCGGCTGTTAC
CGCGGGCTGACCACGAAAGGCGGCCCCAAGGGAGTTGGAACCGCCGTCAACGAAACCCTG
GTGCTGTGCGTGATCGCGCTGTTCGCGACCAATGTGGTGTTGACCACGATCGGCGTGCGG
TTCGGGACGGGACACTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv2711	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002
Interaction	RegulatedBy Rv0586	active	yamir.moreno	2012-10-05
	LacZ-promoter fusion. expression levels of LacZ- regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). Electrophoretic mobility shift assays EMSA. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . MD. Santangelo, F. Blanco et al. Mce2R from Mycobacterium tuberculosis represses the expression of the mce2 operon repressor from M. tuberculosis. Tuberculosis (Edinburgh, Scotland) 2008
Interaction	RegulatedBy Rv0586	active	yamir.moreno	2012-10-05
	LacZ-promoter fusion. expression levels of LacZ- regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). Electrophoretic mobility shift assays EMSA. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . MD. Santangelo, F. Blanco et al. Mce2R from Mycobacterium tuberculosis represses the expression of the mce2 operon repressor from M. tuberculosis. Tuberculosis (Edinburgh, Scotland) 2008