Rv0803 - phosphoribosylformylglycinamidine synthase II purL

Expression: Most Significant Conditions for Rv0803

Protein Domains

Gene Information
Locus	Rv0803
Symbol	purL
Gene Name	phosphoribosylformylglycinamidine synthase II purL
Location	895820 - 898084 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2265 bp Protein:755 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	1012
Related Genes	Acel_2074 BL1108 CE2480 cg2862 DIP2130 jk0355 MAP0635 MAV_0744 Mkms_4633 ML2211 Mmcs_4546 MSMEG_5824 MT0823 MUL_0410 Mvan_5119 nfa5730 PPA1977 SAV4138
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0803
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0803 Transcript 1
MLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYSVMWSEHCSYKSS
KVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATG
VGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETV
FDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFD
AEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDGG
MTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKWEVLATVIGEVTD
GDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADRSAKLSRPVTGDELRA
TLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGMLRIDESTGRGIAVSTDASGRY
TLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCA
DLGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGETLMLLGDTR
DEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIV
ESALAGETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMCEARGLPAVRIGV
VDQGSDAVEVQGLFAVSLAELRATSEAVLPRYFG*

Genomic Sequence

>Rv0803
GTGCTGGACACCGTCGAACACGCCGCGACCACACCCGACCAACCACAACCGTATGGTGAG
CTGGGCCTCAAAGACGACGAGTACCGGCGGATTCGCCAGATCCTGGGCCGCCGGCCCACC
GACACCGAGCTGGCCATGTACTCGGTGATGTGGAGCGAACACTGTTCGTACAAGTCCTCC
AAGGTGCACCTGCGCTACTTCGGTGAGACCACCTCCGACGAGATGCGCGCGGCCATGCTG
GCCGGCATCGGCGAGAACGCCGGCGTCGTCGACATCGGCGACGGCTGGGCGGTCACCTTC
AAGGTGGAGTCACACAACCACCCGTCCTACGTCGAGCCCTACCAGGGCGCGGCCACCGGG
GTGGGCGGCATCGTCCGCGACATCATGGCCATGGGCGCCCGACCGGTCGCCGTGATGGAC
CAGCTTCGGTTCGGCGCCGCCGACGCCCCCGATACCCGCCGCGTGCTCGACGGCGTGGTC
CGCGGCATCGGCGGATACGGCAACTCCCTGGGCCTGCCCAACATTGGCGGAGAGACCGTC
TTCGACCCGTGCTACGCCGGCAACCCCTTAGTGAACGCGTTGTGTGTCGGCGTATTACGG
CAGGAGGACCTGCATTTGGCGTTCGCCTCCGGCGCCGGCAACAAGATCATCCTGTTTGGC
GCGCGCACCGGGCTCGACGGTATCGGCGGGGTGTCGGTGCTGGCGTCGGACACCTTCGAT
GCCGAGGGATCCCGCAAGAAGCTGCCCTCGGTGCAGGTCGGCGACCCGTTCATGGAGAAG
GTGCTCATCGAATGCTGTCTCGAGCTCTACGCGGGCGGCCTGGTGATCGGCATCCAAGAC
CTGGGCGGAGCCGGATTATCTTGTGCCACATCGGAGTTAGCATCCGCCGGTGATGGCGGA
ATGACGATCCAGCTGGACAGCGTCCCGCTGCGGGCCAAGGAGATGACGCCCGCCGAGGTG
CTCTGCAGCGAATCGCAGGAGCGGATGTGCGCGGTGGTCTCCCCGAAGAACGTCGACGCA
TTCCTGGCGGTGTGCCGCAAGTGGGAGGTGCTGGCGACGGTGATCGGCGAGGTCACCGAC
GGCGACCGGCTGCAGATCACCTGGCACGGCGAGACGGTGGTCGACGTGCCGCCGCGCACC
GTAGCTCACGAAGGTCCGGTATATCAGCGCCCGGTCGCCCGCCCCGATACGCAGGACGCG
CTGAACGCCGACCGCTCGGCCAAGCTGTCACGGCCGGTCACCGGCGACGAGCTGCGCGCG
ACTTTGCTTGCGTTACTTGGCAGCCCGCACCTGTGCAGCCGCGCGTTCATCACCGAGCAG
TACGACCGCTATGTGCGCGGCAACACGGTGCTCGCCGAGCACGCCGACGGCGGCATGCTG
CGCATCGACGAGTCGACCGGCCGGGGCATCGCGGTATCGACCGACGCGTCGGGACGCTAC
ACGCTGCTGGATCCCTACGCTGGCGCGCAACTCGCGTTGGCCGAGGCGTACCGCAACGTC
GCCGTCACCGGCGCCACCCCGGTCGCGGTGACCAACTGCCTGAACTTCGGTTCCCCCGAG
GACCCCGGCGTGATGTGGCAGTTCACGCAGGCGGTCCGCGGTCTGGCCGATGGCTGTGCG
GACCTCGGGATTCCGGTGACCGGTGGCAACGTGAGTTTCTACAACCAAACCGGTTCGGCG
GCAATCCTGCCCACGCCGGTGGTCGGGGTGCTCGGCGTCATCGACGATGTGCGTCGGCGC
ATCCCTACCGGCCTGGGCGCCGAGCCCGGGGAAACGTTGATGCTGTTGGGCGACACCCGC
GACGAGTTCGACGGTTCCGTGTGGGCGCAGGTGACCGCAGACCACCTGGGTGGATTGCCG
CCGGTAGTCGATCTGGCGCGGGAGAAGCTGCTGGCCGCGGTGCTGAGCTCGGCGTCGCGG
GACGGGCTAGTGTCCGCGGCGCACGATCTGTCCGAGGGTGGGCTGGCCCAAGCCATCGTG
GAATCGGCGTTAGCGGGTGAAACCGGTTGCCGCATAGTGCTTCCCGAAGGGGCTGACCCG
TTTGTGCTGCTGTTCTCCGAGTCGGCGGGTCGGGTGCTGGTCGCGGTGCCACGCACCGAG
GAGAGCCGGTTTCGCGGGATGTGTGAGGCGCGGGGACTTCCCGCGGTCCGCATCGGCGTC
GTCGATCAAGGTTCGGACGCGGTTGAGGTGCAGGGCTTGTTCGCGGTGTCGTTGGCCGAA
CTGCGTGCGACATCCGAGGCGGTGTTGCCGCGATACTTCGGATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv0616c	active	akankshajain.21	2012-10-05
	Co-expression (Functional linkage) T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Interaction	RegulatedBy Rv0491	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003