Rv0950c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv0950c

Protein Domains

Gene Information
Locus	Rv0950c
Symbol
Gene Name	conserved hypothetical protein
Location	1060656 - 1061654 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:999 bp Protein:333 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	27069
Related Genes	CE0934 cg0980 DIP0836 jk1559 MAP0895c MAV_1073 Mkms_4414 ML0154 Mmcs_4328 MSMEG_5526 MT0977 MUL_4721 Mvan_4871 nfa49920
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0950c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0950c Transcript 1
MAAIRTPRDRWPHHHRNEVTEIIPLDGFLDGLALYDELDFAELDDLDLGDDCVFDYEAQL
LAAPELDDLDDADDLAPEWLVAPTVVLTPEVTPVSRRVGQHRKQPIGAARGRLLISAMAA
GAAAAAAHTAIQQSETPRTETVLTAHASALNEGSGSNPPRGVQVIAAQPAASAAVHNAEF
ARGVAFAEERAEREARLQRPLYVMPTKGIFTSSFGYRWGVLHAGIDLANAIGTPIYAVSD
GVVIDAGPTAGYGMWVKLLHADGTVTLYGHVNTTLVSVGERVMAGDQIATMGSRGFSTGP
HLHFEVLLGGTERVDPVPWLAKRGLSVGNYTG*

Genomic Sequence

>Rv0950c
ATGGCAGCGATTCGCACACCTCGCGATCGTTGGCCGCATCATCACCGTAACGAAGTCACC
GAAATCATCCCGCTGGACGGATTCCTCGACGGCTTAGCACTCTACGATGAGCTGGATTTC
GCAGAGCTCGATGACCTGGACCTAGGGGACGACTGCGTCTTCGACTACGAAGCGCAGTTG
CTAGCGGCTCCAGAACTCGACGACCTGGACGACGCCGACGATCTGGCCCCCGAATGGCTG
GTAGCCCCCACGGTCGTGCTGACCCCGGAGGTCACCCCGGTGTCCCGGCGCGTCGGGCAG
CACCGCAAGCAACCGATCGGTGCGGCCCGGGGGCGCCTGCTGATCTCGGCGATGGCCGCG
GGCGCGGCGGCCGCAGCAGCGCATACGGCGATCCAACAGTCGGAAACCCCACGCACCGAG
ACCGTGCTGACCGCTCATGCATCGGCGCTCAACGAAGGGTCGGGAAGCAACCCACCGCGG
GGCGTCCAGGTCATCGCCGCCCAGCCGGCGGCGAGTGCTGCGGTGCACAACGCGGAGTTC
GCCAGGGGGGTTGCCTTCGCCGAGGAGCGCGCCGAGCGCGAGGCGCGACTACAGCGCCCG
CTGTATGTCATGCCGACGAAGGGCATCTTCACGTCGAGTTTCGGTTATCGATGGGGTGTA
CTGCACGCCGGTATCGACCTGGCTAACGCGATCGGAACCCCGATTTATGCGGTGTCCGAC
GGCGTCGTCATCGACGCCGGCCCCACCGCCGGCTACGGAATGTGGGTCAAGCTGCTGCAC
GCCGACGGCACGGTCACGCTATACGGCCACGTCAATACCACGTTGGTCAGCGTCGGTGAG
CGCGTGATGGCAGGCGACCAGATCGCCACCATGGGCAGCCGTGGCTTTTCCACCGGCCCG
CACCTGCACTTCGAGGTGCTCCTGGGCGGCACCGAGCGCGTGGACCCAGTGCCGTGGCTC
GCCAAGCGGGGACTTAGCGTCGGCAATTACACCGGTTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	sourish10	2012-10-05
	ChIP (Physical interaction) G. Bai, MA. Gazdik et al. The Mycobacterium bovis BCG cyclic AMP receptor-like protein is a functional DNA binding protein in vitro and in vivo, but its activity differs from that of its M. tuberculosis ortholog, Rv3676. Infect. Immun. 2007
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008