Rv0951 - succinyl-CoA synthetase beta chain sucC
Protein Domains

Gene Information
LocusRv0951
SymbolsucC
Gene Namesuccinyl-CoA synthetase beta chain sucC
Location1061964 - 1063127 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1164 bp
Protein:388 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number24789
Related GenesAcel_0380 BL0732 CE2451 cg2837 MAP0896 MAV_1074 Mkms_4413 ML0155 Mmcs_4327 MSMEG_5525 MT0978 MUL_4720 Mvan_4870 nfa49910 PPA1755 SAV3452
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv0951
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv2069activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
TermEC:6.2.1.5 Succinate--CoA ligase (ADP-forming). - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
AD. Baughn, SJ. Garforth et al. An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis. PLoS Pathog. 2009
TermEC:6.2.1.5 Succinate--CoA ligase (ADP-forming). - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011