Rv0957 - bifunctional purine biosynthesis protein purH

Expression: Most Significant Conditions for Rv0957

Protein Domains

Gene Information
Locus	Rv0957
Symbol	purH
Gene Name	bifunctional purine biosynthesis protein purH
Location	1068205 - 1069776 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1572 bp Protein:524 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	385
Related Genes	Acel_0384 BL0735 CE0937 cg0984 DIP0839 jk1556 MAP0903 MAV_1081 Mkms_4405 ML0161 Mmcs_4319 MSMEG_5515 MT0984 MUL_4712 Mvan_4856 nfa49860 PPA1747 SAV3444
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0957
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0957 Transcript 1
MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL
TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG
ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL
AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT
AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA
HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV
LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA
CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE
TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH*

Genomic Sequence

>Rv0957
ATGAGCACCGACGACGGAAGACGGCCGATCCGCCGTGCGCTGATCAGCGTGTACGACAAG
ACCGGGCTGGTAGACCTGGCACAGGGCCTGAGCGCGGCCGGCGTCGAGATCATCTCGACT
GGGTCAACGGCCAAGACCATTGCCGACACCGGGATTCCGGTGACCCCCGTGGAGCAGCTG
ACCGGCTTTCCCGAGGTGCTCGATGGCCGGGTCAAGACACTGCACCCACGAGTGCATGCC
GGGCTGCTGGCTGACCTGCGCAAGTCCGAGCACGCCGCGGCCCTCGAGCAACTCGGGATC
GAGGCTTTCGAACTCGTTGTAGTCAACTTGTATCCGTTCAGCCAGACCGTCGAATCCGGC
GCCAGTGTCGACGACTGCGTCGAGCAGATTGATATCGGCGGGCCGGCGATGGTGCGGGCC
GCCGCCAAAAACCATCCCAGCGCGGCGGTGGTCACCGATCCGCTTGGGTACCATGGCGTG
CTTGCCGCACTGCGCGCCGGCGGATTCACCCTCGCCGAGCGCAAAAGGCTGGCGTCGTTA
GCGTTTCAGCATATAGCCGAGTACGACATCGCCGTCGCGAGCTGGATGCAACAGACCCTA
GCGCCCGAACATCCTGTTGCCGCCTTTCCGCAGTGGTTCGGCCGAAGCTGGCGCCGCGTG
GCGATGCTGCGCTACGGCGAGAACCCGCACCAACAGGCCGCTCTCTACGGCGACCCCACC
GCCTGGCCGGGGCTGGCCCAGGCCGAGCAACTGCACGGAAAAGACATGTCCTACAACAAC
TTCACCGATGCGGACGCAGCCTGGCGGGCCGCCTTCGACCACGAACAAACGTGCGTGGCG
ATCATCAAGCACGCCAACCCGTGCGGCATCGCAATCTCGTCCGTTTCGGTCGCCGACGCG
CATCGCAAGGCTCACGAATGCGATCCGCTGAGCGCCTACGGCGGGGTCATCGCCGCCAAT
ACCGAGGTCAGTGTCGAAATGGCCGAGTATGTGAGCACCATCTTCACCGAAGTCATCGTC
GCGCCTGGCTACGCCCCCGGGGCCCTCGATGTGCTGGCCCGCAAGAAGAACATCCGGGTG
CTGGTAGCCGCCGAGCCACTGGCCGGTGGCAGCGAGTTGCGTCCGATCAGCGGTGGACTG
CTGATACAGCAGAGCGACCAGCTTGACGCGCACGGTGACAACCCGGCGAACTGGACCTTG
GCGACCGGGTCACCTGCGGACCCCGCGACGCTGACCGACCTGGTCTTCGCGTGGCGAGCC
TGCCGTGCGGTCAAGTCGAACGCGATAGTGATAGCTGCCGACGGCGCCACCGTCGGCGTC
GGGATGGGTCAGGTCAACCGTGTCGACGCCGCCCGGTTGGCCGTCGAACGCGGCGGCGAG
CGGGTTCGCGGCGCGGTGGCAGCCTCGGATGCGTTCTTCCCCTTTCCCGACGGCCTGGAA
ACGTTGGCCGCCGCGGGGGTCACCGCGGTCGTCCACCCCGGTGGCTCGGTGCGCGACGAG
GAAGTGACCGAAGCGGCGGCCAAGGCCGGTGTCACCCTATATCTCACCGGGGCGCGGCAC
TTCGCGCACTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv0772	active	jgalag	2012-10-05
	Functional Linkage(Operon) authors,A. Aiba,K. Mizobuchi Nucleotide sequence analysis of genes purH and purD involved in the de novo purine nucleotide biosynthesis of Escherichia coli. J. Biol. Chem. 1989
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006