Rv1017c - ribose-phosphate pyrophosphokinase prsA

Expression: Most Significant Conditions for Rv1017c

Protein Domains

Gene Information
Locus	Rv1017c
Symbol	prsA
Gene Name	ribose-phosphate pyrophosphokinase prsA
Location	1135501 - 1136481 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:981 bp Protein:327 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32552
Related Genes	Acel_1946 BL0963 CE1015 cg1075 DIP0903 jk1493 MAP0983c MAV_1156 Mkms_4335 ML0248 Mmcs_4249 MSMEG_5427 MT1045 MUL_4638 Mvan_4783 nfa48790 PPA0531 SAV3562
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1017c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1017c Transcript 1
MSHDWTDNRKNLMLFAGRAHPELAEQVAKELDVHVTSQDAREFANGEIFVRFHESVRGCD
AFVLQSCPAPVNRWLMEQLIMIDALKRGSAKRITAVMPFYPYARQDKKHRGREPISARLI
ADLLKTAGADRIVTVDLHTDQIQGFFDGPVDHMRGQNLLTGYIRDNYPDGNMVVVSPDSG
RVRIAEKWADALGGVPLAFIHKTRDPRVPNQVVSNRVVGDVAGRTCVLIDDMIDTGGTIA
GAVALLHNDGAGDVIIAATHGVLSDPAAQRLASCGAREVIVTNTLPIGEDKRFPQLTVLS
IAPLLASTIRAVFENGSVTGLFDGDA*

Genomic Sequence

>Rv1017c
TTGAGCCACGACTGGACCGATAATCGCAAAAACCTGATGCTCTTTGCCGGCCGCGCCCAT
CCGGAGCTGGCCGAGCAGGTAGCCAAAGAGCTCGACGTCCACGTCACCTCTCAGGACGCG
CGGGAGTTCGCCAACGGCGAGATCTTCGTGCGCTTCCACGAATCGGTACGCGGTTGCGAC
GCCTTCGTCCTGCAATCCTGCCCGGCACCGGTGAACAGGTGGCTGATGGAACAGCTGATC
ATGATCGACGCGCTCAAACGGGGCAGCGCCAAACGGATCACCGCCGTCATGCCGTTCTAT
CCGTATGCCCGGCAAGACAAGAAACACCGTGGCCGCGAACCGATCTCCGCGCGACTGATC
GCCGACCTGCTCAAGACCGCGGGCGCCGACCGGATCGTGACGGTCGACCTGCACACCGAC
CAGATCCAGGGTTTCTTCGACGGGCCGGTCGATCATATGCGCGGTCAGAACCTGCTGACC
GGTTACATCAGAGACAACTACCCGGACGGCAACATGGTGGTCGTCTCCCCTGACTCCGGC
CGGGTACGCATCGCCGAGAAGTGGGCCGACGCATTAGGTGGTGTTCCCCTCGCCTTCATC
CACAAGACCCGTGATCCGCGGGTACCCAACCAAGTGGTGTCCAACCGCGTCGTCGGCGAC
GTGGCCGGGCGCACCTGTGTCCTGATTGACGACATGATCGACACCGGCGGCACCATCGCC
GGCGCGGTGGCATTGCTGCACAACGACGGCGCCGGTGACGTGATCATCGCGGCAACCCAC
GGCGTGCTCTCCGACCCCGCTGCGCAGCGGCTGGCCTCCTGCGGCGCCCGCGAAGTGATC
GTCACGAACACGCTCCCGATCGGCGAAGACAAGCGCTTCCCCCAGCTCACCGTTTTGTCC
ATCGCGCCGCTGCTGGCCAGCACAATCCGGGCGGTCTTCGAAAACGGCTCAGTAACAGGA
CTTTTCGACGGGGACGCATAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006