Rv1032c - two component system sensor histidine kinase trcS

Expression: Most Significant Conditions for Rv1032c

Protein Domains

Gene Information
Locus	Rv1032c
Symbol	trcS
Gene Name	two component system sensor histidine kinase trcS
Location	1156426 - 1157955 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1530 bp Protein:510 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	36866
Related Genes	jk1272 MAP1001c MAV_1175 Mkms_0722 Mmcs_0708 MSMEG_0993 MT1061 MUL_4625 Mvan_0884
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1032c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1032c Transcript 1
MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV
ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE
DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII
ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR
PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA
ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN
AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH
RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR
GSVTAESGNGQTVFRVRLPMIEQQIATTA*

Genomic Sequence

>Rv1032c
ATGATCCCGGACCGAAACACTCGGTCCAGAAAAGCCCCCTGCTGGCGACCCCGCTCGTTA
CGCCAGCAATTGCTGCTCGGCGTGTTGGCGGTCGTTACCGTTGTGCTGGTGGCCGTCGGT
GTCGTCTCCGTGCTGAGCCTAAGCGGCTATGTCACCGCGATGAACGACGCCGAGCTAGTC
GAATCCCTGCACGCGTTGAACCACTCTTACACCAGATACCGCGACAGTGCGCAAACATCC
ACGCCCACCGGCAACCTCCCGATGTCACAAGCGGTGCTGGAGTTCACCGGCCAGACGCCC
GGAAACCTCATTGCCGTGCTGCACGACGGCGTGGTGATCGGATCGGCCGTTTTCTCCGAA
GACGGAGCACGACCCGCTCCGCCCGACGTCATCCGCGCGATCGAAGCGCAAGTGTGGGAC
GGCGGCCCGCCGCGTGTCGAAAGCCTGGGCAGCCTGGGCGCCTACCAGGTTGACAGCAGC
GCCGCTGGCGCCGATCGACTGTTCGTCGGCGTATCGCTAAGCCTGGCCAACCAGATCATC
GCCCGCAAGAAAGTCACCACCGTCGCGCTTGTTGGGGCCGCACTGGTGGTTACCGCAGCA
CTGACGGTGTGGGTGGTGGGATATGCGCTACGCCCGCTGCGCCGGGTCGCCGCGACCGCC
GCCGAGGTCGCCACCATGCCACTTACCGATGACGACCACCAGATCAGCGTGCGAGTCCGT
CCGGGGGATACCGACCCGGATAACGAGGTCGGAATCGTCGGGCACACGCTGAATCGCTTG
TTGGACAACGTCGATGGTGCGCTGGCGCATCGCGTCGATTCCGATCTGCGGATGCGGCAG
TTCATCACCGACGCCAGCCACGAGCTGCGTACTCCCCTGGCGGCGATCCAGGGCTATGCC
GAACTGACACGTCAGGATAGCTCGGACCTACCGCCCACCACCGAATACGCGCTGGCCCGC
ATCGAATCCGAGGCGCGGCGGATGACGCTGCTGGTCGACGAGCTGCTGCTGCTCTCCCGT
CTCAGCGAGGGCGAAGATCTAGAAACCGAGGACCTCGACCTGACCGACCTGGTCATCAAC
GCGGTGAATGACGCGGCGGTTGCGGCGCCCACCCACCGTTGGGTGAAGAATCTGCCCGAC
GAGCCGGTCTGGGTCAACGGGGATCATGCCCGCTTGCATCAACTCGTCAGCAATCTACTC
ACCAATGCCTGGGTGCATACCCAGCCCGGCGTCACAGTGACCATCGGGATCACCTGCCAC
CGCACTGGTCCCAACGCGCCGTGTGTTGAATTGTCGGTGACCGACGACGGCCCCGACATC
GACCCGGAGATCCTGCCCCACCTCTTCGACCGGTTCGTGCGGGCCAGCAAGTCTCGGTCC
AATGGGTCCGGCCACGGCTTGGGCCTGGCCATCGTCAGCTCGATCGTCAAGGCGCATCGC
GGCTCGGTCACGGCCGAGTCGGGCAACGGCCAGACGGTGTTTCGGGTGCGGCTCCCGATG
ATCGAGCAGCAGATCGCCACTACCGCCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Inhibits Rv1057	active	ashwinigbhat	2012-10-05
	DNase I and hydroxyl radical footprinting analyses SE. Haydel & JE. Clark-Curtiss The Mycobacterium tuberculosis TrcR response regulator represses transcription of the intracellularly expressed Rv1057 gene, encoding a seven-bladed beta-propeller. J. Bacteriol. 2006
Interaction	Regulatory Rv1033c	active	akankshajain.21	2012-10-05
	Co-expression (Functional linkage) L. Wernisch, SL. Kendall et al. Analysis of whole-genome microarray replicates using mixed models. Bioinformatics 2003
Interaction	Regulatory Rv1033c	active	akankshajain.21	2012-10-05
	Co-expression (Functional linkage) SE. Haydel, NE. Dunlap et al. In vitro evidence of two-component system phosphorylation between the Mycobacterium tuberculosis TrcR/TrcS proteins. Microb. Pathog. 1999
Interaction	Regulatory Rv1033c	active	darhngu	2012-10-05
	Co-expression (Functional linkage) L. Wernisch, SL. Kendall et al. Analysis of whole-genome microarray replicates using mixed models. Bioinformatics 2003
Interaction	Regulatory Rv1033c	active	darhngu	2012-10-05
	Co-expression (Functional linkage) SE. Haydel, NE. Dunlap et al. In vitro evidence of two-component system phosphorylation between the Mycobacterium tuberculosis TrcR/TrcS proteins. Microb. Pathog. 1999