Rv1296 - homoserine kinase thrB

Expression: Most Significant Conditions for Rv1296

Protein Domains

Gene Information
Locus	Rv1296
Symbol	thrB
Gene Name	homoserine kinase thrB
Location	1451997 - 1452947 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:951 bp Protein:317 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	512
Related Genes	Acel_0632 BL1275 CE1290 cg1338 DIP1037 jk1350 MAP2466c MAV_1511 Mkms_3968 ML1131 Mmcs_3894 MSMEG_4955 MT1335 MUL_3968 Mvan_4346 nfa10510 PPA1256 SAV2916
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1296
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1296 Transcript 1
MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD
QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV
VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI
RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ
PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL
TVGEAVRWSPTVRVPG*

Genomic Sequence

>Rv1296
ATGGTGACTCAAGCATTGTTGCCTTCTGGGCTGGTGGCCAGTGCGGTGGTGGCGGCGTCC
AGTGCAAACCTGGGCCCGGGCTTCGACAGTGTCGGTTTGGCGCTGAGTCTCTACGACGAG
ATCATCGTCGAGACAACAGATTCCGGCTTGACGGTGACTGTAGACGGCGAGGGCGGCGAC
CAGGTGCCGCTGGGCCCCGAGCACCTCGTGGTCCGCGCCGTGCAGCACGGGTTACAGGCA
GCGGGGGTCAGCGCCGCCGGCCTGGCGGTGCGCTGCCGCAACGCCATCCCGCACTCCCGC
GGCCTCGGCTCCTCCGCGGCAGCAGTTGTGGGCGGTCTTGCGGCCGTTAACGGTCTTGTC
GTACAAACGGATTCGTCACCATCGAGCGATGCTGAGCTGATTCAGTTGGCTTCGGAGTTC
GAGGGTCATCCCGACAACGCGGCGGCCGCGGTTTTGGGTGGTGCCGTGGTTTCGTGGACT
GACCACAGTGGTGACCGGCCCAACTATTCGGCCGTATCACTGCGGCTTCATCCCGATATC
CGCCTGTTCACTGCGATTCCCGAGCAGCGTTCGTCGACCGCGGAAACGCGGGTGCTATTG
CCCGCGCAGGTTAGTCACGACGACGCACGGTTCAATGTCAGTCGCGCGGCGCTGCTGGTG
GTTGCGCTCACCGAACGGCCCGATCTGCTGATGGCGGCCACCGAAGATCTGCTTCATCAG
CCGCAACGTGCCGCGGCAATGACAGCCTCCGCGGAATATCTTCGGCTGTTGCGGCGTCAT
AACGTGGCAGCAGCACTGTCCGGGGCAGGTCCTTCGTTGATCGCCCTGAGTACAGATTCA
GAGTTGCCGACCGACGCCGTGGAGTTCGGAGCCGCAAAGGGATTTGCCGTTACCGAGCTG
ACTGTTGGCGAGGCGGTTCGCTGGAGCCCGACAGTAAGAGTTCCCGGTTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3286c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007
Term	EC:2.7.1.39 Homoserine kinase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,M. Fernández,Y. Cuadrado,E. Recio,JF. Aparicio,JF. Martín Characterization of the hom-thrC-thrB cluster in aminoethoxyvinylglycine-producing Streptomyces sp. NRRL 5331. Microbiology (Reading, Engl.) 2002