Rv1348 - drugs-transport transmembrane ATP-binding protein ABC transporter

Expression: Most Significant Conditions for Rv1348

Protein Domains

Gene Information
Locus	Rv1348
Symbol
Gene Name	drugs-transport transmembrane ATP-binding protein ABC transporter
Location	1513047 - 1515626 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2580 bp Protein:860 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	37898
Related Genes	MAP2413c MAP2414c MAV_1566 MAV_1567 Mkms_4039 Mmcs_3965 MSMEG_5039 MT1390 MT1392 MUL_3901 MUL_3902 Mvan_4468 nfa46920 nfa46940 Rv1349
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1348
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1348 Transcript 1
MARGLQGVMLRSFGARDHTATVIETISIAPHFVRVRMVSPTLFQDAEAEPAAWLRFWFPD
PNGSNTEFQRAYTISEADPAAGRFAVDVVLHDPAGPASSWARTVKPGATIAVMSLMGSSR
FDVPEEQPAGYLLIGDSASIPGMNGIIETVPNDVPIEMYLEQHDDNDTLIPLAKHPRLRV
RWVMRRDEKSLAEAIENRDWSDWYAWATPEAAALKCVRVRLRDEFGFPKSEIHAQAYWNA
GRAMGTHRATEPAATEPEVGAAPQPESAVPAPARGSWRAQAASRLLAPLKLPLVLSGVLA
ALVTLAQLAPFVLLVELSRLLVSGAGAHRLFTVGFAAVGLLGTGALLAAALTLWLHVIDA
RFARALRLRLLSKLSRLPLGWFTSRGSGSIKKLVTDDTLALHYLVTHAVPDAVAAVVAPV
GVLVYLFVVDWRVALVLFGPVLVYLTITSSLTIQSGPRIVQAQRWAEKMNGEAGSYLEGQ
PVIRVFGAASSSFRRRLDEYIGFLVAWQRPLAGKKTLMDLATRPATFLWLIAATGTLLVA
THRMDPVNLLPFMFLGTTFGARLLGIAYGLGGLRTGLLAARHLQVTLDETELAVREHPRE
PLDGEAPATVVFDHVTFGYRPGVPVIQDVSLTLRPGTVTALVGPSGSGKSTLATLLARFH
DVERGAIRVGGQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAA
REAQIHDRVLRLPDGYDTVLGANSGLSGGERQRLTIARAILGDTPVLILDEATAFADPES
EYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHGRIVERGTHEELLAAGGRYCRL
WDTGQGSRVAVAAAQDGTR*

Genomic Sequence

>Rv1348
ATGGCACGCGGGTTGCAGGGTGTGATGTTGCGCAGTTTCGGCGCGCGCGACCACACCGCA
ACGGTGATCGAAACCATTTCGATTGCACCGCATTTCGTGCGGGTCCGGATGGTTTCGCCG
ACGCTCTTCCAGGATGCGGAGGCTGAGCCCGCCGCATGGCTGCGGTTCTGGTTCCCCGAC
CCGAACGGGTCCAACACCGAGTTCCAGCGCGCCTATACGATCTCCGAAGCTGACCCCGCC
GCGGGCCGCTTCGCGGTCGACGTTGTATTGCATGACCCGGCGGGTCCGGCCTCGTCGTGG
GCGCGCACCGTCAAACCTGGCGCAACCATAGCGGTCATGTCGCTGATGGGCTCATCGCGG
TTCGACGTGCCCGAGGAGCAGCCCGCCGGGTATCTGCTAATCGGCGACTCGGCGTCGATT
CCGGGGATGAACGGGATCATCGAAACGGTCCCGAACGACGTCCCGATCGAGATGTACCTT
GAACAACACGACGACAACGACACGTTGATCCCGCTCGCAAAGCATCCCCGGCTGCGGGTG
CGCTGGGTTATGCGCCGCGACGAGAAATCGCTGGCCGAGGCGATCGAGAACCGCGACTGG
TCGGACTGGTATGCGTGGGCGACGCCAGAGGCTGCCGCGCTGAAATGCGTCCGGGTGCGG
CTGCGCGACGAGTTCGGGTTCCCTAAGTCCGAGATCCACGCTCAGGCTTACTGGAACGCC
GGGCGTGCCATGGGCACCCACCGAGCAACCGAACCGGCGGCCACCGAACCTGAGGTGGGC
GCAGCCCCGCAGCCAGAATCGGCGGTGCCTGCCCCGGCGCGTGGCAGCTGGCGCGCTCAG
GCTGCCAGCCGGCTGCTGGCGCCGCTAAAGCTGCCGCTGGTGCTCTCGGGTGTGCTTGCG
GCTCTGGTCACGCTGGCGCAGTTGGCGCCGTTCGTGCTGTTGGTCGAGCTGTCAAGGCTG
CTGGTCTCCGGCGCCGGCGCGCACCGGTTGTTCACGGTCGGGTTCGCCGCGGTGGGGTTG
CTGGGGACCGGGGCCTTGCTGGCAGCCGCCCTCACGCTGTGGCTGCACGTGATCGATGCC
CGCTTCGCCAGGGCGTTGCGCTTGCGGCTGCTGAGCAAGCTGTCCCGGTTGCCGCTGGGC
TGGTTCACCAGCCGCGGGTCCGGATCGATCAAAAAATTGGTCACCGACGACACGCTGGCG
TTGCACTACTTGGTCACCCATGCCGTTCCGGACGCGGTCGCCGCGGTTGTCGCCCCGGTG
GGGGTGCTGGTCTATCTGTTCGTCGTGGACTGGCGAGTGGCGCTGGTCTTGTTCGGGCCG
GTTCTGGTCTACCTGACCATCACGTCATCGCTCACGATCCAATCCGGGCCCCGCATTGTT
CAAGCGCAGCGGTGGGCAGAGAAGATGAACGGCGAAGCGGGTAGTTACCTCGAGGGTCAG
CCGGTGATTCGCGTCTTCGGCGCCGCGTCATCGAGCTTCCGTCGCCGGTTGGACGAGTAC
ATCGGATTCCTGGTCGCCTGGCAGCGGCCGCTGGCCGGCAAGAAAACCCTGATGGATCTG
GCCACTCGCCCAGCAACGTTCCTGTGGCTCATCGCCGCTACCGGCACCTTGTTGGTAGCC
ACGCATCGAATGGATCCGGTGAATTTGTTGCCGTTCATGTTCTTGGGTACCACGTTCGGT
GCCCGCCTGCTCGGGATCGCCTACGGGCTCGGCGGCCTACGCACGGGACTTCTGGCGGCC
CGGCACCTGCAAGTCACACTCGACGAAACCGAACTCGCCGTGCGGGAACATCCGCGCGAA
CCGCTCGACGGCGAGGCGCCAGCAACTGTGGTGTTCGACCACGTCACCTTCGGGTACCGC
CCTGGAGTGCCGGTGATCCAGGATGTATCGCTTACGCTGCGGCCGGGCACGGTCACCGCG
CTCGTCGGCCCGTCCGGCTCCGGCAAGTCGACACTGGCCACCCTGCTGGCTCGATTCCAC
GATGTCGAGCGAGGTGCGATACGCGTTGGTGGACAGGATATTCGATCACTGGCCGCGGAC
GAGCTGTACACGCGAGTCGGCTTTGTGCTACAGGAAGCCCAGCTTGTGCATGGCACCGCC
GCCGAAAACATCGCGCTGGCGGTACCGGATGCCCCCGCCGAACAGGTCCAGGTCGCGGCC
CGCGAAGCGCAAATCCACGACCGGGTGCTTCGGCTGCCGGACGGCTACGATACCGTGCTC
GGAGCCAACAGTGGTCTTTCGGGCGGGGAGCGACAGCGGCTCACCATTGCCCGTGCCATC
CTCGGCGACACTCCGGTCCTCATCCTCGACGAGGCCACCGCGTTTGCCGATCCGGAATCG
GAATACCTTGTGCAACAGGCGCTTAACCGGCTGACCCGGGACCGCACCGTGCTGGTAATC
GCCCATCGACTGCATACCATCACCCGGGCCGACCAGATCGTCGTGCTCGATCATGGTCGG
ATCGTCGAACGCGGCACCCACGAGGAGTTGCTTGCCGCGGGCGGACGCTACTGCCGGCTG
TGGGACACCGGCCAGGGCAGCCGGGTGGCGGTCGCCGCAGCGCAGGACGGCACCCGATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv1349	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) GM. Rodriguez & I. Smith Identification of an ABC transporter required for iron acquisition and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2006
Interaction	Regulatory Rv2711	active	shahanup86	2012-10-05
	Co-expression (Functional linkage) GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002
Interaction	PhysicalInteraction Rv1349	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) MB. Ryndak,S. Wang,I. Smith,GM. Rodriguez The Mycobacterium tuberculosis high-affinity iron importer, IrtA, contains an FAD-binding domain. J. Bacteriol. 2010
Interaction	PhysicalInteraction Rv1349	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) GM. Rodriguez & I. Smith Identification of an ABC transporter required for iron acquisition and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2006
Interaction	RegulatedBy Rv2711	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008