Rv1380 - aspartate carbamoyltransferase pyrB

Expression: Most Significant Conditions for Rv1380

Protein Domains

Gene Information
Locus	Rv1380
Symbol	pyrB
Gene Name	aspartate carbamoyltransferase pyrB
Location	1553232 - 1554191 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:960 bp Protein:320 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33455
Related Genes	Acel_1301 BL0794 CE1732 cg1816 DIP1334 jk1025 MAP1115 MAV_3393 Mkms_2410 ML0532 Mmcs_2363 MSMEG_3043 MT1424 MUL_1780 Mvan_2660 nfa36230 PPA0997 SAV6863
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1380
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1380 Transcript 1
MTPRHLLTAADLSRDDATAILDDADRFAQALVGRDIKKLPTLRGRTVVTMFYENSTRTRV
SFEVAGKWMSADVINVSAAGSSVGKGESLRDTALTLRAAGADALIIRHPASGAAHLLAQW
TGAHNDGPAVINAGDGTHEHPTQALLDALTIRQRLGGIEGRRIVIVGDILHSRVARSNVM
LLDTLGAEVVLVAPPTLLPVGVTGWPATVSHDFDAELPAADAVLMLRVQAERMNGGFFPS
VREYSVRYGLTERRQAMLPGHAVVLHPGPMVRGMEITSSVADSSQSAVLQQVSNGVQVRM
AVLFHVLVGAQDAGKEGAA*

Genomic Sequence

>Rv1380
ATGACCCCAAGGCACCTGCTGACCGCCGCCGACCTCAGCCGCGACGACGCCACCGCCATC
CTCGACGACGCCGACCGGTTTGCGCAGGCGCTGGTCGGTCGCGACATCAAGAAGCTGCCG
ACGCTGCGGGGCCGGACCGTCGTCACGATGTTCTATGAGAACTCCACCCGCACCCGGGTG
TCGTTCGAGGTAGCGGGTAAGTGGATGAGCGCCGACGTGATCAACGTCAGCGCTGCCGGA
TCTTCGGTAGGCAAGGGTGAGTCGCTGCGGGATACCGCGCTGACCCTGCGCGCGGCCGGG
GCTGACGCGCTGATCATCCGCCATCCCGCGTCCGGCGCCGCCCATCTGCTGGCGCAGTGG
ACCGGCGCCCACAACGATGGGCCGGCGGTGATCAACGCCGGTGACGGCACTCATGAACAC
CCCACGCAGGCGCTGCTTGATGCGCTGACCATCCGTCAGCGCCTCGGCGGCATCGAAGGC
CGGCGCATCGTGATCGTCGGCGACATCCTGCACAGCCGGGTCGCCCGCTCCAACGTCATG
CTGCTGGACACCCTGGGCGCCGAGGTGGTGCTGGTGGCGCCACCCACATTGCTACCGGTC
GGGGTGACCGGCTGGCCGGCCACCGTCTCCCACGACTTCGATGCCGAGCTGCCCGCCGCC
GACGCGGTATTGATGCTGCGGGTACAGGCCGAGCGGATGAACGGCGGTTTTTTCCCGTCC
GTACGGGAGTACTCGGTCCGCTACGGGCTAACCGAGCGGCGCCAGGCGATGCTTCCCGGC
CACGCCGTGGTGTTGCACCCGGGACCGATGGTGCGTGGCATGGAGATCACATCTTCGGTC
GCGGACTCGTCGCAATCGGCTGTGCTGCAACAGGTTTCCAATGGAGTCCAGGTGCGGATG
GCGGTGCTGTTCCATGTGCTGGTGGGAGCGCAGGATGCCGGTAAAGAGGGTGCGGCGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv1379	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) authors,CJ. Fields,RL. Switzer Regulation of pyr gene expression in Mycobacterium smegmatis by PyrR-dependent translational repression. J. Bacteriol. 2007
Interaction	Regulatory Rv1379	active	shahanup86	2012-10-05
	Structural Analysis authors,CJ. Fields,RL. Switzer Regulation of pyr gene expression in Mycobacterium smegmatis by PyrR-dependent translational repression. J. Bacteriol. 2007
Interaction	Regulatory Rv1379	active	shahanup86	2012-10-05
	Structural Analysis KA. Kantardjieff, C. Vasquez et al. Structure of pyrR (Rv1379) from Mycobacterium tuberculosis: a persistence gene and protein drug target. Acta Crystallogr. D Biol. Crystallogr. 2005
Interaction	Regulatory Rv1379	active	shahanup86	2012-10-05
	Spectrophotometric authors,CJ. Fields,RL. Switzer Regulation of pyr gene expression in Mycobacterium smegmatis by PyrR-dependent translational repression. J. Bacteriol. 2007
Interaction	Regulatory Rv1379	active	shahanup86	2012-10-05
	Spectrophotometric KA. Kantardjieff, C. Vasquez et al. Structure of pyrR (Rv1379) from Mycobacterium tuberculosis: a persistence gene and protein drug target. Acta Crystallogr. D Biol. Crystallogr. 2005
Interaction	RegulatedBy Rv1379	active	yamir.moreno	2012-10-05
	Protein structure based inferences. the regulation is infered after the observation of protein structure. KA. Kantardjieff, C. Vasquez et al. Structure of pyrR (Rv1379) from Mycobacterium tuberculosis: a persistence gene and protein drug target. Acta Crystallogr. D Biol. Crystallogr. 2005