Rv1461 - conserved hypothetical protein

Expression: Most Significant Conditions for Rv1461

Protein Domains

Gene Information
Locus	Rv1461
Symbol
Gene Name	conserved hypothetical protein
Location	1646989 - 1649529 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2541 bp Protein:847 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	35145
Related Genes	BL0871 BL0872 Mkms_2481 Mkms_2482 ML0593 Mmcs_2436 Mmcs_2437 MSMEG_3122 MSMEG_3123 MT1508 MUL_1862 MUL_1863 Mvan_2733 Mvan_2734 nfa35590 nfa35600 Rv1462
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1461
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1461 Transcript 1
MTLTPEASKSVAQPPTQAPLTQEEAIASLGRYGYGWADSDVAGANAQRGLSEAVVRDISA
KKNEPDWMLQSRLKALRIFDRKPIPKWGSNLDGIDFDNIKYFVRSTEKQAASWDDLPEDI
RNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEAQGVIFLDTDTGLREHPDIFK
EYFGTVIPAGDNKFSALNTAVWSGGSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLII
ADEGSYVHYVEGCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGE
LFTFTPMSPANAFSVTAEHPLLAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKD
VAEGDFLIYPKPKPIPHRTVLPLEFARLAGYYLAEGHACLTNGCESLIFSFHSDEFEYVE
DVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDNVGIGSSNKKLSDLLMRQDE
TFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYATVELRRPGGP
GVIMGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPD
SYLAYGFAVHNCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARAE
AGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEDQHQDTGAKMLHLAPNTS
SNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTVSRSDTYPYVDIREDDV
TMGHEATVSKVSENQLFYLMSRGLTEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQ
MEGAVG*

Genomic Sequence

>Rv1461
ATGACACTCACCCCAGAGGCCAGCAAGAGCGTTGCCCAGCCCCCGACCCAGGCTCCCCTG
ACCCAGGAAGAGGCGATCGCGTCGCTGGGCCGGTACGGCTACGGCTGGGCGGACTCCGAC
GTCGCGGGTGCCAACGCGCAGCGCGGGCTTTCCGAGGCGGTGGTCCGCGACATCTCCGCG
AAGAAGAACGAGCCCGATTGGATGCTGCAGTCGCGGCTGAAGGCGCTGCGCATTTTCGAC
CGCAAGCCCATTCCGAAGTGGGGCTCCAACCTCGATGGCATCGATTTCGACAACATCAAG
TACTTCGTGCGCTCCACCGAGAAGCAGGCCGCGAGCTGGGATGATTTGCCAGAGGACATC
CGCAACACCTACGACCGGTTGGGAATCCCGGAGGCCGAGAAGCAGAGATTAGTAGCTGGA
GTAGCCGCACAATACGAAAGTGAAGTTGTATATCACCAGATCAGAGAGGATCTGGAGGCT
CAAGGAGTCATATTTTTAGACACTGATACTGGTTTGCGAGAACACCCGGATATTTTCAAG
GAATATTTCGGTACAGTAATCCCTGCCGGCGATAATAAGTTTTCTGCATTGAATACTGCA
GTTTGGAGTGGTGGGTCCTTTATTTACGTCCCGCCCGGTGTTCACGTCGACATTCCGCTG
CAGGCCTACTTCCGAATCAACACCGAGAACATGGGCCAGTTCGAGCGGACGCTGATCATC
GCCGATGAGGGCTCTTACGTGCACTACGTAGAGGGCTGCCTGCCCGCCGGCGAGCTCATC
ACGACCGCCGACGGCGATTTGCGGCCCATCGAGTCGATTCGCGTCGGTGACTTCGTCACC
GGCCACGACGGGCGGCCACACCGCGTCACCGCTGTACAGGTGCGTGACCTCGATGGCGAG
CTGTTCACCTTCACACCGATGTCGCCTGCCAACGCATTCTCTGTCACCGCCGAGCACCCC
CTTCTCGCTATTCCCCGCGACGAGGTGCGTGTTATGCGGAAGGAACGCAATGGGTGGAAG
GCTGAAGTCAACAGCACCAAGCTGCGTAGCGCCGAGCCGCGATGGATCGCGGCGAAGGAT
GTGGCCGAGGGTGACTTCCTGATCTACCCCAAGCCGAAGCCGATCCCCCACAGGACGGTT
TTGCCGCTCGAGTTTGCGCGCCTGGCGGGCTACTACCTGGCGGAGGGTCACGCGTGTCTC
ACCAATGGCTGTGAGTCGCTGATCTTCTCGTTCCACAGCGATGAGTTCGAGTACGTCGAG
GATGTGCGCCAAGCGTGCAAGTCGCTGTACGAGAAGTCGGGATCGGTATTGATCGAGGAG
CACAAGCATTCGGCGCGCGTCACCGTGTACACGAAGGCGGGCTATGCGGCGATGCGCGAC
AACGTCGGCATTGGATCGTCGAATAAGAAGCTGTCGGATCTGTTGATGCGTCAAGACGAG
ACGTTCTTGCGTGAGCTGGTCGACGCCTATGTGAATGGAGACGGCAACGTCACGCGCCGT
AACGGGGCGGTGTGGAAGCGGGTACATACGACATCGCGCCTCTGGGCGTTCCAGTTGCAG
TCCATCCTGGCGCGTCTGGGTCACTACGCCACTGTTGAACTGCGCCGACCGGGCGGCCCT
GGTGTGATCATGGGCCGCAACGTCGTTCGCAAGGACATCTACCAGGTGCAGTGGACCGAG
GGCGGCCGCGGACCGAAGCAGGCCCGCGACTGCGGCGACTACTTTGCGGTGCCAATCAAG
AAGCGAGCGGTCCGCGAAGCACATGAGCCCGTCTACAACCTCGATGTCGAGAATCCGGAC
AGCTACCTCGCCTACGGGTTCGCCGTGCACAACTGCACCGCACCGATCTACAAATCGGAT
TCATTGCACTCAGCGGTGGTCGAGATCATCGTGAAACCCCATGCGCGCGTGCGTTACACC
ACCATCCAGAACTGGTCGAACAACGTCTACAACCTGGTCACCAAGCGGGCCCGCGCCGAA
GCCGGGGCCACCATGGAGTGGATCGACGGCAACATCGGGTCCAAGGTGACCATGAAGTAC
CCGGCGGTCTGGATGACCGGCGAGCACGCCAAGGGCGAAGTGCTCTCGGTGGCGTTCGCC
GGCGAAGACCAGCACCAGGACACCGGCGCCAAGATGCTGCACCTGGCGCCGAACACGTCG
AGCAACATCGTGTCCAAGTCGGTGGCCCGCGGCGGCGGCCGCACCTCCTACCGTGGCCTG
GTGCAGGTCAACAAGGGGGCGCATGGGTCGCGGTCCAGCGTGAAATGCGATGCGCTGCTG
GTGGATACGGTCAGCCGCAGCGACACCTACCCCTACGTCGACATCCGCGAGGACGACGTC
ACCATGGGCCACGAGGCCACCGTGTCCAAGGTCAGCGAGAACCAGCTGTTCTACCTGATG
AGCCGCGGGCTGACCGAGGACGAGGCGATGGCGATGGTGGTGCGCGGCTTCGTCGAGCCG
ATCGCCAAGGAGCTGCCGATGGAGTACGCGCTGGAGCTCAACCGGCTGATCGAGCTGCAG
ATGGAGGGCGCGGTCGGATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv1463	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,M. Daffé,I. Saves Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival. J. Bacteriol. 2005
Interaction	PhysicalInteraction Rv1463	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) B. Murugasu-Oei, A. Tay et al. Upregulation of stress response genes and ABC transporters in anaerobic stationary-phase Mycobacterium smegmatis. Mol. Gen. Genet. 1999
Interaction	PhysicalInteraction Rv1462	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,M. Daffé,I. Saves Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival. J. Bacteriol. 2005
Interaction	Regulatory Rv1464	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,JP. Castaing,D. Fournier,M. Daffé,I. Saves Protein splicing of SufB is crucial for the functionality of the Mycobacterium tuberculosis SUF machinery. J. Bacteriol. 2006
Interaction	Regulatory Rv1463	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,JP. Castaing,D. Fournier,M. Daffé,I. Saves Protein splicing of SufB is crucial for the functionality of the Mycobacterium tuberculosis SUF machinery. J. Bacteriol. 2006
Interaction	Regulatory Rv1462	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,JP. Castaing,D. Fournier,M. Daffé,I. Saves Protein splicing of SufB is crucial for the functionality of the Mycobacterium tuberculosis SUF machinery. J. Bacteriol. 2006
Interaction	Regulatory Rv1464	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,M. Daffé,I. Saves Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival. J. Bacteriol. 2005
Interaction	Regulatory Rv1463	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,M. Daffé,I. Saves Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival. J. Bacteriol. 2005
Interaction	Regulatory Rv1462	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,G. Huet,M. Daffé,I. Saves Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival. J. Bacteriol. 2005
Interaction	RegulatedBy Rv0348	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
Interaction	RegulatedBy Rv3557c	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
Interaction	RegulatedBy Rv3416	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
Interaction	RegulatedBy Rv1931c	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
Interaction	RegulatedBy Rv1359	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
Interaction	RegulatedBy Rv0818	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
Interaction	RegulatedBy Rv0445c	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
Interaction	RegulatedBy Rv0260c	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009