Rv1475c - iron-regulated aconitate hydratase acn


Protein Domains

Gene Information
LocusRv1475c
Symbolacn
Gene Nameiron-regulated aconitate hydratase acn
Location1663215 - 1666046 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:2832 bp
Protein:944 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number13890
Related GenesAcel_1394 BL1397 CE1661 cg1737 DIP1283 jk0969 MAP1201c MAV_3303 Mkms_2494 ML1814 Mmcs_2449 MSMEG_3143 MT1522 MUL_1484 Mvan_2745 nfa34830 PPA1061 SAV2258
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
TermEC:4.2.1.3 Aconitate hydratase. - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
S. Banerjee, AK. Nandyala et al. Iron-dependent RNA-binding activity of Mycobacterium tuberculosis aconitase. J. Bacteriol. 2007
TermEC:4.2.1.3 Aconitate hydratase. - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011
TermEC:4.2.1.3 Aconitate hydratase. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
EJ. Muñoz-Elías, AM. Upton et al. Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence. Mol. Microbiol. 2006
TermEC:4.2.1.99 2-methylisocitrate dehydratase. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
EJ. Muñoz-Elías, AM. Upton et al. Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence. Mol. Microbiol. 2006