Rv1536 - isoleucyl-tRNA synthetase ileS

Expression: Most Significant Conditions for Rv1536

Protein Domains

Gene Information
Locus	Rv1536
Symbol	ileS
Gene Name	isoleucyl-tRNA synthetase ileS
Location	1736519 - 1739644 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:3126 bp Protein:1042 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33595
Related Genes	Acel_1029 BL1777 CE2043 cg2359 DIP1589 jk0760 MAP1246 MAV_3235 Mkms_3160 ML1195 Mmcs_3100 MSMEG_3169 MT1587 MUL_1532 Mvan_2769 nfa17760 PPA0216 SAV6130
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1536
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1536 Transcript 1
MTDNAYPKLAGGAPDLPALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPH
YGHLLTGYVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMGIAA
FNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWAFKQLWDKGLAYEG
YRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVGFKVVGGQPDNGLDGAYLLVWTTT
PWTLPSNLAVAVSPDITYVQVQAGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGT
RYLPPFAYFMDWPNAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIAPVTPVDS
KGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIRHETYEHPYPHCWRCRNP
LIYRSVSSWFVRVTDFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRNRYWGTP
IPVWKSDDPAYPRIDVYGSLDELERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIP
DVLDVWFDSGSMPYAQVHYPFENLDWFQGHYPGDFIVEYIGQTRGWFYTLHVLATALFDR
PAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDAMRWFLMASPILRGGNLIVT
EQGIRDGVRQVLLPLWNTYSFLALYAPKVGTWRVDSVHVLDRYILAKLAVLRDDLSESME
VYDIPGACEHLRQFTEALTNWYVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLIT
EIIWRGLTRERSVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLP
KLIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGPRLGKDVQAA
IKAVKAGDGVINPDGTLLAGPAVLTPDEYNSRLVAADPESTAALPDGAGLVVLDGTVTAE
LEAEGWAKDRIRELQELRKSTGLDVSDRIRVVMSVPAEREDWARTHRDLIAGEILATDFE
FADLADGVAIGDGVRVSIEKT*

Genomic Sequence

>Rv1536
GTGACCGATAACGCATATCCAAAGCTGGCCGGCGGGGCACCCGACCTCCCGGCACTCGAA
CTCGAGGTCCTCGACTACTGGTCCCGTGACGACACCTTCCGGGCCAGCATTGCTCGCCGC
GATGGCGCCCCCGAGTATGTGTTCTATGACGGGCCGCCGTTTGCCAACGGTCTGCCGCAT
TATGGGCACCTGCTCACCGGCTACGTCAAAGACATCGTGCCGCGATATCGCACTATGCGC
GGTTACAAGGTGGAGCGTCGCTTCGGCTGGGACACTCACGGGCTGCCCGCCGAACTCGAA
GTCGAGCGCCAGCTTGGCATCACTGACAAATCCCAGATCGAGGCCATGGGTATCGCCGCC
TTCAACGATGCCTGCCGCGCATCCGTGTTGCGCTACACCGACGAGTGGCAGGCGTATGTA
ACTCGGCAAGCTCGCTGGGTCGACTTCGACAACGATTACAAGACGCTCGATCTGGCTTAC
ATGGAGTCGGTGATTTGGGCCTTCAAACAGTTGTGGGACAAGGGCCTGGCCTACGAGGGC
TACCGGGTGCTGCCGTACTGCTGGCGCGACGAAACTCCGCTGTCGAATCACGAACTGCGG
ATGGACGACGACGTCTACCAAAGCCGCCAAGATCCCGCGGTAACGGTGGGCTTCAAGGTG
GTGGGTGGCCAACCAGACAACGGGCTAGACGGTGCCTACTTGCTGGTGTGGACGACGACT
CCGTGGACCCTGCCGTCGAACCTCGCAGTTGCGGTAAGCCCGGACATCACCTACGTACAG
GTCCAGGCGGGCGATCGCCGTTTCGTACTGGCCGAGGCACGGCTGGCCGCTTACGCCCGC
GAACTCGGTGAAGAGCCCGTGGTGCTCGGCACCTATCGCGGCGCCGAACTGCTGGGCACC
CGCTACCTGCCGCCGTTTGCCTATTTCATGGACTGGCCCAACGCTTTTCAGGTGCTAGCA
GGCGACTTTGTAACGACCGACGATGGCACCGGCATCGTGCATATGGCACCGGCCTATGGT
GAGGACGACATGGTGGTCGCGGAGGCGGTCGGTATCGCGCCGGTGACTCCGGTCGACTCC
AAGGGACGCTTCGACGTCACCGTTGCCGATTACCAAGGGCAGCATGTCTTTGACGCCAAC
GCGCAGATCGTCCGGGACCTGAAGACCCAAAGCGGCCCGGCTGCGGTGAATGGCCCAGTG
TTGATTCGTCACGAAACCTACGAGCACCCTTACCCACACTGCTGGCGATGCCGTAACCCG
CTGATCTACCGGTCGGTGTCGTCGTGGTTCGTCAGGGTGACGGACTTCCGAGACCGCATG
GTGGAGCTAAACCAGCAGATCACGTGGTATCCCGAACACGTCAAGGACGGCCAGTTCGGC
AAGTGGCTGCAGGGCGCCCGCGATTGGTCGATCTCCCGGAATCGCTACTGGGGTACCCCG
ATTCCGGTATGGAAGTCCGACGACCCGGCCTACCCGCGCATCGATGTCTACGGCAGCCTC
GACGAGCTGGAGCGCGACTTCGGCGTACGCCCGGCCAATTTGCACCGGCCCTACATCGAC
GAGCTCACCCGTCCCAACCCAGACGATCCGACTGGCCGTAGCACGATGCGACGCATTCCC
GATGTGCTCGACGTGTGGTTCGACTCGGGATCCATGCCGTATGCCCAGGTGCACTACCCG
TTCGAGAACCTGGATTGGTTCCAGGGACACTACCCCGGCGACTTCATCGTCGAGTACATC
GGGCAGACCCGTGGCTGGTTTTACACACTGCATGTGTTGGCGACCGCGCTCTTTGACCGG
CCGGCATTCAAAACCTGTGTGGCGCATGGGATTGTCCTTGGTTTCGATGGCCAGAAGATG
AGCAAGTCGCTGCGCAACTATCCAGACGTAACAGAGGTGTTCGATCGCGACGGCTCCGAC
GCCATGCGGTGGTTCCTGATGGCATCGCCGATTCTGCGCGGCGGCAACCTGATCGTCACT
GAGCAAGGAATTCGCGACGGTGTGCGACAAGTCCTGCTGCCCCTGTGGAACACCTACAGC
TTCCTGGCGCTGTATGCACCGAAAGTCGGTACCTGGCGCGTCGATTCGGTGCACGTGCTG
GATCGCTATATCCTGGCCAAGCTGGCGGTGCTGCGCGACGACCTCAGCGAGTCGATGGAA
GTTTACGATATTCCCGGTGCCTGTGAACATTTGCGTCAGTTCACTGAGGCGTTGACTAAT
TGGTATGTGCGACGGTCGCGTTCGCGGTTCTGGGCAGAAGACGCCGATGCCATCGACACG
CTACACACCGTGTTGGAGGTGACCACGAGGCTGGCCGCCCCGCTGCTTCCGCTGATCACC
GAGATAATCTGGCGTGGTCTGACACGCGAGCGATCGGTGCACCTGACGGACTGGCCAGCG
CCCGACCTGCTGCCGTCGGATGCCGACCTGGTCGCCGCGATGGACCAGGTCCGCGACGTG
TGCTCGGCGGCATCCTCGCTGCGCAAGGCCAAGAAGCTACGGGTGCGCCTGCCGCTACCG
AAACTCATTGTGGCAGTTGAGAATCCGCAACTTCTGAGGCCGTTCGTCGACCTCATTGGC
GACGAGCTTAACGTGAAGCAGGTCGAACTGACCGATGCCATCGACACCTATGGCCGATTC
GAGCTCACGGTCAACGCCCGGGTAGCCGGACCACGGCTGGGCAAAGATGTGCAGGCCGCC
ATCAAGGCGGTCAAGGCCGGCGACGGCGTCATAAACCCGGACGGCACCTTGTTGGCGGGC
CCCGCGGTGCTGACGCCCGACGAGTACAACTCCCGGCTGGTGGCCGCCGACCCGGAGTCC
ACCGCGGCGTTGCCCGACGGCGCCGGGCTGGTCGTTCTGGATGGCACCGTCACTGCCGAA
CTCGAAGCCGAGGGCTGGGCCAAAGATCGCATCCGCGAACTGCAAGAGCTGCGTAAGTCG
ACCGGGCTGGACGTTTCCGACCGCATCCGGGTGGTGATGTCGGTGCCTGCGGAACGCGAA
GACTGGGCGCGCACCCATCGCGACCTCATTGCCGGAGAAATCTTGGCTACCGACTTCGAA
TTCGCCGACCTCGCCGATGGTGTGGCCATCGGCGACGGCGTGCGGGTAAGCATCGAAAAG
ACCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv1221	active	shahanup86	2012-10-05
	Co-expression (Functional linkage) R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
Interaction	RegulatedBy Rv3286c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007