Rv1611 - indole-3-glycerol phosphate synthase trpC

Expression: Most Significant Conditions for Rv1611

Protein Domains

Gene Information
Locus	Rv1611
Symbol	trpC
Gene Name	indole-3-glycerol phosphate synthase trpC
Location	1810240 - 1811058 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:819 bp Protein:273 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	28422
Related Genes	Acel_1073 CE1991 cg2293 DIP1555 jk0797 MAP1305 MAV_3175 Mkms_3110 ML1271 Mmcs_3051 MSMEG_3219 MT1646 MUL_1591 Mvan_2816 nfa18600 PPA1130 SAV6175
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1611
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1611 Transcript 1
MSPATVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKR
ASPSAGALATIADPAKLAQAYQDGGARIVSVVTEQRRFQGSLDDLDAVRASVSIPVLRKD
FVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMTALVEVHTEQEADRALK
AGAKVIGVNARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVL
VGEGLVTSGDPRAAVADLVTAGTHPSCPKPAR*

Genomic Sequence

>Rv1611
ATGAGTCCGGCAACCGTGCTCGACTCCATCCTCGAGGGAGTCCGGGCCGACGTTGCCGCG
CGTGAAGCCTCGGTGAGCCTGTCGGAGATCAAGGCTGCCGCCGCTGCGGCGCCGCCGCCG
CTCGACGTGATGGCCGCCCTACGCGAGCCCGGCATCGGCGTCATCGCTGAGGTCAAGCGC
GCTAGTCCTTCGGCAGGCGCATTGGCGACCATCGCCGACCCGGCAAAGCTGGCCCAGGCC
TACCAGGATGGCGGTGCCCGGATCGTCAGCGTGGTGACTGAGCAGCGGCGTTTTCAGGGA
TCGCTCGACGACCTCGACGCGGTGCGGGCCTCGGTTTCGATTCCGGTGCTGCGCAAGGAC
TTTGTGGTGCAGCCGTACCAGATTCATGAGGCGCGTGCGCACGGCGCCGACATGTTGTTG
CTCATCGTCGCCGCATTGGAGCAGTCGGTGTTGGTGTCGATGTTGGACCGCACCGAATCG
TTGGGTATGACAGCACTCGTCGAGGTCCATACCGAGCAGGAAGCCGACCGAGCGCTGAAG
GCCGGGGCCAAGGTGATTGGCGTTAACGCCCGCGACCTCATGACGCTGGACGTGGACCGG
GATTGCTTCGCGCGAATAGCTCCTGGTTTGCCGAGCAGTGTGATCAGGATTGCTGAATCC
GGCGTGCGTGGCACCGCTGACCTGCTGGCGTACGCCGGCGCGGGCGCTGACGCGGTGTTG
GTAGGCGAAGGTCTGGTCACCAGCGGCGACCCACGTGCCGCGGTTGCCGATCTGGTTACC
GCGGGCACCCATCCGTCCTGTCCGAAACCGGCTCGCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Operon Rv1613	active	harsharohiratruefriend	2012-10-05
	operon authors,DS. Hu,DW. Hood,R. Heidstra,DA. Hodgson The expression of the trpD, trpC and trpBA genes of Streptomyces coelicolor A3(2) is regulated by growth rate and growth phase but not by feedback repression. Mol. Microbiol. 1999
Interaction	RegulatedBy Rv2710	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. JH. Lee, PC. Karakousis et al. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. J. Bacteriol. 2008
Term	EC:4.1.1.48 Indole-3-glycerol-phosphate synthase. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein purified to homogeneity from its native host Y. Yang, M. Zhang et al. Purification and characterization of Mycobacterium tuberculosis indole-3-glycerol phosphate synthase. Biochemistry Mosc. 2006