Rv1613 - tryptophan synthase, alpha subunit trpA

Expression: Most Significant Conditions for Rv1613

Protein Domains

Gene Information
Locus	Rv1613
Symbol	trpA
Gene Name	tryptophan synthase, alpha subunit trpA
Location	1812359 - 1813171 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:813 bp Protein:271 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	1172
Related Genes	Acel_1075 BL0755 CE2873 cg3364 DIP2361 jk0799 MAP1307 MAV_3173 Mkms_3108 ML1273 Mmcs_3049 MSMEG_3221 MT1648 MUL_1593 Mvan_2818 nfa18620 PPA1132 SAV6178
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1613
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1613 Transcript 1
MVAVEQSEASRLGPVFDSCRANNRAALIGYLPTGYPDVPASVAAMTALVESGCDIIEVGV
PYSDPGMDGPTIARATEAALRGGVRVRDTLAAVEAISIAGGRAVVMTYWNPVLRYGVDAF
ARDLAAAGGLGLITPDLIPDEAQQWLAASEEHRLDRIFLVAPSSTPERLAATVEASRGFV
YAASTMGVTGARDAVSQAAPELVGRVKAVSDIPVGVGLGVRSRAQAAQIAQYADGVIVGS
ALVTALTEGLPRLRALTGELAAGVRLGMSA*

Genomic Sequence

>Rv1613
ATGGTGGCGGTGGAACAGAGCGAAGCAAGTAGGCTCGGGCCGGTTTTCGATTCCTGCCGT
GCAAACAACCGCGCGGCATTGATTGGTTACTTGCCGACCGGGTACCCGGACGTGCCAGCG
TCGGTGGCCGCGATGACAGCGCTAGTTGAATCCGGTTGCGACATTATCGAAGTCGGGGTT
CCGTATTCGGACCCGGGCATGGACGGCCCCACCATCGCCAGGGCAACCGAGGCGGCGCTC
CGTGGCGGGGTGCGAGTCCGGGATACGTTAGCCGCGGTCGAGGCCATCAGTATCGCCGGC
GGGCGTGCGGTAGTGATGACCTACTGGAATCCGGTGCTGCGCTATGGGGTTGATGCATTC
GCGCGGGATCTGGCGGCGGCCGGAGGACTCGGCCTGATCACTCCTGACCTCATTCCCGAC
GAGGCGCAACAGTGGCTGGCGGCATCCGAAGAGCATCGGTTGGATCGCATTTTCTTGGTC
GCGCCGTCCTCGACACCGGAGCGGTTGGCGGCCACCGTCGAGGCTTCACGCGGGTTCGTC
TACGCGGCGTCGACGATGGGGGTGACCGGGGCGCGGGATGCGGTGTCGCAGGCGGCACCC
GAACTGGTGGGCCGGGTGAAGGCGGTGTCTGACATACCGGTGGGCGTCGGTCTGGGTGTG
CGGTCGCGCGCTCAAGCCGCGCAGATCGCCCAATACGCCGACGGTGTCATCGTTGGTTCC
GCATTGGTGACGGCGCTAACCGAGGGGTTGCCTAGATTGCGGGCACTGACCGGAGAGCTC
GCTGCCGGGGTACGACTAGGGATGTCCGCATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Operon Rv1611	active	harsharohiratruefriend	2012-10-05
	operon authors,DS. Hu,DW. Hood,R. Heidstra,DA. Hodgson The expression of the trpD, trpC and trpBA genes of Streptomyces coelicolor A3(2) is regulated by growth rate and growth phase but not by feedback repression. Mol. Microbiol. 1999
Interaction	Operon Rv1612	active	harsharohiratruefriend	2012-10-05
	operon authors,DS. Hu,DW. Hood,R. Heidstra,DA. Hodgson The expression of the trpD, trpC and trpBA genes of Streptomyces coelicolor A3(2) is regulated by growth rate and growth phase but not by feedback repression. Mol. Microbiol. 1999
Interaction	RegulatedBy Rv0348	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009