Rv1617 - pyruvate kinase pykA


Protein Domains

Gene Information
LocusRv1617
SymbolpykA
Gene Namepyruvate kinase pykA
Location1816189 - 1817607 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1419 bp
Protein:473 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number33509
Related GenesAcel_1080 BL0988 CE1989 cg2291 DIP1553 jk0801 MAP1310 MAV_3170 Mkms_3101 ML1277 Mmcs_3042 MSMEG_3227 MT1653 MUL_1598 Mvan_2824 nfa18650 PPA0769 SAV6217
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv1617
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatedBy Rv1785cactiveyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv1785cactiveyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
TermEC:2.7.1.40 Pyruvate kinase. - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
S. Chavadi,E. Wooff,NG. Coldham,M. Sritharan,RG. Hewinson,SV. Gordon,PR. Wheeler Global effects of inactivation of the pyruvate kinase gene in the Mycobacterium tuberculosis complex. J. Bacteriol. 2009
TermEC:2.7.1.40 Pyruvate kinase. - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011