Rv1661 - polyketide synthase pks7
Protein Domains

Gene Information
LocusRv1661
Symbolpks7
Gene Namepolyketide synthase pks7
Location1875304 - 1881684 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:6381 bp
Protein:2127 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number36280
Related GenesAcel_1266 BL1065 MAP1370 MAP1371 MAV_3107 MAV_3108 MAV_3109 MT1701 MT1702 MT1704 MUL_1655 Rv1662 Rv1664 SAV6741 SAV6754 SAV6757
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv1661
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionPhysicalInteraction Rv1663activevashishtrv2012-10-05
Co-expression (Functional Linkage)
VS. Dubey, TD. Sirakova et al. Biochemical function of msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv: biosynthesis of monomethyl branched unsaturated fatty acids. J. Bacteriol. 2003
InteractionPhysicalInteraction Rv1663activevashishtrv2012-10-05
Co-expression (Functional Linkage)
authors,G. Yadav,RS. Gokhale,D. Mohanty SEARCHPKS: A program for detection and analysis of polyketide synthase domains. Nucleic Acids Res. 2003
InteractionPhysicalInteraction Rv1663activevashishtrv2012-10-05
Co-expression (Functional Linkage)
MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
InteractionPhysicalInteraction Rv1663activeshahanup862012-10-05
Co-expression (Functional Linkage)
VS. Dubey, TD. Sirakova et al. Biochemical function of msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv: biosynthesis of monomethyl branched unsaturated fatty acids. J. Bacteriol. 2003
InteractionPhysicalInteraction Rv1663activeshahanup862012-10-05
Co-expression (Functional Linkage)
authors,G. Yadav,RS. Gokhale,D. Mohanty SEARCHPKS: A program for detection and analysis of polyketide synthase domains. Nucleic Acids Res. 2003
InteractionPhysicalInteraction Rv1663activeshahanup862012-10-05
Co-expression (Functional Linkage)
MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
InteractionRegulatory Rv0735activevashishtrv2012-10-05
Co-expression (Functional Linkage)
authors,G. Yadav,RS. Gokhale,D. Mohanty SEARCHPKS: A program for detection and analysis of polyketide synthase domains. Nucleic Acids Res. 2003
InteractionRegulatory Rv0735activevashishtrv2012-10-05
Co-expression (Functional Linkage)
MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
InteractionRegulatory Rv0735activeshahanup862012-10-05
Co-expression (Functional Linkage)
authors,G. Yadav,RS. Gokhale,D. Mohanty SEARCHPKS: A program for detection and analysis of polyketide synthase domains. Nucleic Acids Res. 2003
InteractionRegulatory Rv0735activeshahanup862012-10-05
Co-expression (Functional Linkage)
MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
InteractionOperon Rv1660activevashishtrv2012-10-05
Co-expression (Functional Linkage)
authors,G. Yadav,RS. Gokhale,D. Mohanty SEARCHPKS: A program for detection and analysis of polyketide synthase domains. Nucleic Acids Res. 2003
InteractionOperon Rv1660activevashishtrv2012-10-05
Co-expression (Functional Linkage)
MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
InteractionOperon Rv1660activeshahanup862012-10-05
Co-expression (Functional Linkage)
authors,G. Yadav,RS. Gokhale,D. Mohanty SEARCHPKS: A program for detection and analysis of polyketide synthase domains. Nucleic Acids Res. 2003
InteractionOperon Rv1660activeshahanup862012-10-05
Co-expression (Functional Linkage)
MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
InteractionOperon Rv1660activeharsharohiratruefriend2012-10-05
operon
TD. Sirakova, VS. Dubey et al. Attenuation of Mycobacterium tuberculosis by disruption of a mas-like gene or a chalcone synthase-like gene, which causes deficiency in dimycocerosyl phthiocerol synthesis. J. Bacteriol. 2003
OtherEC:activejjmcfadden2012-03-05
Inferred from direct assay
P. Constant, E. Perez et al. Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene. J. Biol. Chem. 2002