Rv1696 - DNA repair protein recN

Expression: Most Significant Conditions for Rv1696

Protein Domains

Gene Information
Locus	Rv1696
Symbol	recN
Gene Name	DNA repair protein recN
Location	1919683 - 1921446 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1764 bp Protein:588 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	625
Related Genes	Acel_1245 BL1043 CE1548 cg1602 DIP1182 jk0866 MAP1403 MAV_3075 Mkms_2993 ML1360 Mmcs_2949 MT1735 MUL_1685 Mvan_3288 nfa19980 PPA1394 SAV6499
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1696
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1696 Transcript 1
MLTELRIESLGAISVATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGARADATRVRSGAD
RAVVEGRFTTTDLDDATVAGLQAVLDSSGAERDEDGSVIALRSISRDGPSRAYLGGRGVP
AKSLSGFTNELLTLHGQNDQLRLMRPDEQRGALDRFAAAGEAVQRYRKLRDAWLTARRDL
VDRRNRARELAQEADRLKFALNEIDTVDPQPGEDVALVADIARLSELDTLREAATTARAT
LCGTPDADAFDRGAVDSLGRARAALQSSDDAALRGLAEQVGEALTVVVDAVAELGAYLDE
LPADASALDAKLARQAQLRTLTRKYAADIDGVLRWADEARARLAQLDVSEEGLAALERRT
GELAHELGQAAVDLSTIRRKAAKRLAKEVSAELSALAMADAEFTIGVTTELADHGDPVAL
ALASGELARAGADGVDAVEFGFVAHRGMTVLPLAKSASGGELSRVMLSLEVVLATSRKQA
AGTTMVFDEIDAGVGGWAAVQIGRRLARLARTHQVIVVTHLPQVAAYADVHLMVQRTGRD
GASGVRRLTSEDRVAELARMLAGLGDSDSGRAHARELLETAQNDELT*

Genomic Sequence

>Rv1696
GTGTTGACTGAATTACGGATCGAGTCGCTGGGCGCCATCAGCGTTGCCACCGCTGAGTTC
GATCGCGGCTTTACCGTGCTGACCGGGGAGACCGGCACCGGCAAGACCATGGTGGTGACC
GGGCTGCACCTACTTGGTGGTGCCCGGGCCGATGCAACTCGCGTTCGGTCCGGTGCTGAC
CGTGCCGTTGTCGAAGGGCGTTTTACTACAACCGATCTCGACGACGCGACCGTCGCGGGG
CTGCAGGCGGTTCTCGACTCGTCGGGGGCCGAGCGCGACGAGGACGGCAGCGTGATCGCG
TTGCGCTCGATCAGTCGCGATGGACCGTCGCGCGCCTACCTCGGCGGCCGCGGTGTACCC
GCCAAATCGTTGAGCGGTTTCACGAACGAGCTGCTTACTCTGCACGGGCAGAACGACCAG
CTGCGGTTGATGCGCCCGGACGAACAACGTGGTGCACTGGACCGCTTTGCGGCCGCTGGC
GAAGCCGTCCAGCGTTACCGCAAGCTGCGGGATGCCTGGCTAACGGCCCGACGCGACCTC
GTCGACCGTCGCAACCGGGCCCGGGAACTAGCGCAAGAGGCCGATCGGCTGAAATTCGCG
CTCAACGAGATCGACACCGTCGACCCGCAGCCGGGGGAGGACGTGGCGTTGGTCGCCGAC
ATCGCCCGGCTTTCCGAACTGGACACCCTGCGGGAGGCCGCGACTACTGCACGCGCGACG
TTGTGCGGGACACCAGACGCGGACGCATTCGACCGCGGCGCCGTCGACAGCCTCGGGCGG
GCACGTGCGGCACTGCAATCGAGCGATGATGCCGCGTTGCGGGGGTTGGCCGAACAGGTC
GGTGAGGCGTTGACGGTGGTCGTCGATGCGGTCGCCGAGCTCGGCGCCTACCTGGACGAG
CTGCCCGCCGACGCCAGCGCGCTGGACGCCAAGCTGGCGCGCCAAGCCCAGCTGCGAACG
TTAACCCGCAAGTACGCCGCCGACATCGATGGCGTGCTCCGGTGGGCGGATGAGGCGAGG
GCAAGGCTGGCTCAACTCGACGTCTCCGAAGAAGGGCTGGCAGCGCTGGAACGCCGTACC
GGTGAGCTCGCCCACGAATTAGGCCAAGCCGCAGTTGATCTCAGCACGATCCGGCGGAAG
GCGGCCAAGCGGCTGGCCAAGGAGGTCAGCGCGGAGCTGTCCGCCCTGGCGATGGCCGAT
GCCGAATTCACCATCGGTGTGACCACAGAGCTGGCCGACCACGGCGATCCCGTCGCCTTG
GCCCTGGCGTCGGGCGAATTGGCCCGGGCCGGTGCCGATGGCGTCGATGCGGTCGAGTTC
GGTTTCGTCGCACACCGGGGGATGACAGTGCTGCCGCTGGCCAAGAGCGCATCCGGCGGC
GAACTGTCCCGGGTGATGTTGTCCCTGGAGGTGGTGCTGGCTACTTCGCGAAAACAAGCG
GCTGGCACCACGATGGTGTTCGACGAGATCGACGCCGGCGTCGGCGGCTGGGCTGCGGTA
CAGATCGGGCGGCGGCTGGCGCGGTTGGCTCGCACCCACCAGGTCATCGTGGTCACCCAT
CTGCCGCAGGTCGCCGCCTATGCCGATGTGCACTTGATGGTGCAGCGCACCGGGCGCGAC
GGTGCCAGCGGTGTGCGGCGCCTGACCAGCGAGGATCGGGTGGCCGAGCTGGCACGGATG
CTGGCCGGGCTTGGTGATTCCGACAGTGGTCGCGCGCACGCGCGGGAGTTACTCGAGACC
GCGCAGAACGACGAGCTCACCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv0735	active	salluamity1	2012-10-05
	Co-expression (Functional linkage) MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
Interaction	Regulatory Rv3286c	active	salluamity1	2012-10-05
	Co-expression (Functional linkage) JH. Lee, DE. Geiman et al. Role of stress response sigma factor SigG in Mycobacterium tuberculosis. J. Bacteriol. 2008
Interaction	RegulatedBy Rv2720	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv2720	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Other	TBPWY:Recombination repair	active	vmizrahi	2012-03-05
	Increased expression in Mtb from clinical lung samples