Rv1790 - PPE family protein


Protein Domains

Gene Information
LocusRv1790
SymbolPPE27
Gene NamePPE family protein
Location2028425 - 2029477 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1053 bp
Protein:351 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number11798
Related GenesMT1839
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
SymbolPPE25-PE19activejlew2012-03-07
Mutant is defective in ESXN and PPE41 secretion. Mutant is attenuated in macrophages and SCID mice.
authors,D. Bottai,M. Di Luca,L. Majlessi,W. Frigui,R. Simeone,F. Sayes,W. Bitter,MJ. Brennan,C. Leclerc,G. Batoni,M. Campa,R. Brosch,S. Esin Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation. Molecular microbiology 2012