Rv1940 - riboflavin biosynthesis protein ribA1

Expression: Most Significant Conditions for Rv1940

Protein Domains

Gene Information
Locus	Rv1940
Symbol	ribA1
Gene Name	riboflavin biosynthesis protein ribA1
Location	2192606 - 2193667 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1062 bp Protein:354 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	28451
Related Genes	MT1990 MUL_2886 Mvan_4000 PPA1750
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1940
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1940 Transcript 1
MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL
PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH
VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE
HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG
AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF
ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG*

Genomic Sequence

>Rv1940
ATGAAGACGACCGATGTGCGGGTACGTCGTGCGATCACGGCGATGGCGGGCGGTCACGCC
GTGGTCCTGACCGGCGACCCCAATGGCGATGGCTATCTCGTCTTCGCCGCCCAGGCCGCG
ACGCCGCGGCTGGTTGCCTTTGCGGTCCGGCACACCTCGGGTTATTTGCGCGTCGCGCTG
CCGGGCGCCGAATGCGAGCGACTGCACCTGCCGCCCATGTGTGACCGAGACACCACGCAT
TGCGTGTCGGTCGACGTTCGCGGCACCGGCACCGGAATCTCGGCGAGCGATCGCGCCTGG
ACCATCGCGGCACTGGCTTCGGCCACCTCCGTCGCCGCCGATTTCCAACGTCCGGGCCAT
GTGGTGCCCGTGCAGGCGCAAGCCGACGGTGTGCTGGGTCGGCGGGGACCCGCCGAGGCG
GCCGTCGACCTGGCCCGCCTGGCGGAACGGCGGCCGGCCGCCGCGCTCTGCGAGATCGTC
TCGCCCGATAATCCCGTCCAGATGGCGCACCACGCCGAGTCGGTCGAATTCGCCGTCGAA
CACGGACTGGCCATGGTCTCGATCGGGGAGCTGGTGGCGTATCGCCGGCGGATCGAGCCC
CAGGTGGTCCGGTTTACGGCAGCGACGCTGCCCACCTGGGCCGGCGCCTCGCGTGTCATC
GGCTTTCGTGACGTTTACGACCTCGGCGAGCATTTGGCGGTCATCGTGGGTGCGGTCGGT
GCCGGGGTGCCCGTGCCGCTGCACGTCCACATCGAGTGCCTGACGGGCGACGTGTTCGGC
TCGACGGCGTGCCGCTGCGGCGAGGAACTCAACGGCGCGCTGGCGAGGATGTCGGCTCAG
GGCAGCGGCGTGGTCTTGTATCTGCGTCCGCCCGGACCCGCGCAAGCGTGCGGCTTGTTC
GCCCGGGGCGATGCGGCGACCGATGTCATGCCGGAGACCGTGACATGGATCCTGCGCGAT
CTTGGGGTGTATGCGATCCGACTTTCCGATGATGTGCCAGGATTTGGGCTTGTCATGTTC
GGGGCGATCCGAGAAGCCAGCACGTTGGCGGCCGCAGGTTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv1963c	active	akankshajain.21	2012-10-05
	Co-expression (Functional linkage) MD. Santangelo, LI. Klepp et al. Mce3R, a TetR-type transcriptional repressor, controls the expression of a regulon involved in lipid metabolism in Mycobacterium tuberculosis. Microbiology (Reading, Engl.) 2009
Interaction	RegulatedBy Rv1963c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. qRT-PCR. mRNA expression levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using qRT-PCR technique. MP. Santangelo, FC. Blanco et al. Study of the role of Mce3R on the transcription of mce genes of Mycobacterium tuberculosis. BMC Microbiol. 2008
Interaction	RegulatedBy Rv1963c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. qRT-PCR. mRNA expression levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using qRT-PCR technique. MP. Santangelo, FC. Blanco et al. Study of the role of Mce3R on the transcription of mce genes of Mycobacterium tuberculosis. BMC Microbiol. 2008