Rv1966 - MCE-family protein mce3A

Expression: Most Significant Conditions for Rv1966

Protein Domains

Gene Information
Locus	Rv1966
Symbol	mce3A
Gene Name	MCE-family protein mce3A
Location	2209327 - 2210604 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1278 bp Protein:426 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	22735
Related Genes	MAV_2532 MT2018 Mvan_3982
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1966
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1966 Transcript 1
MRRGPGRHRLHDAWWTLILFAVIGVAVLVTAVSFTGSLRSTVPVTLAADRSGLVMDSGAK
VMMRGVQVGRVAQIGRIEWAQNGASLRLEIDPDQIRYIPANVEAQISATTAFGAKFVDLV
MPQNPSRARLSAGAVLHSKNVSTEINTVFENVVDLLNMIDPLKLNAVLTAVADAVRGQGE
RIGQATTDLNEVLEALNARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVVN
HSTQLDALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKYNPEYTCFLQGAKW
YLDNGGYAAWGGADGRTLQLDVALLFGNDPYVYPDNLPVVAAKGGPGGRPGCGPLPDATH
NFPVRQLVTNTGWGTGLDIRPNPGIGHPCWANYFPVTRAVPEPPSIRQCIPGPAIGPNPA
AGEQP*

Genomic Sequence

>Rv1966
ATGAGACGCGGGCCGGGTCGACACCGTTTGCACGACGCGTGGTGGACGCTGATCCTGTTC
GCGGTGATCGGGGTGGCTGTCCTGGTGACGGCGGTGTCCTTCACGGGCAGCTTGCGGTCG
ACTGTGCCGGTGACGCTGGCGGCCGACCGCTCCGGGCTGGTGATGGACTCCGGCGCCAAG
GTCATGATGCGCGGTGTGCAGGTCGGCCGGGTCGCCCAGATCGGTCGGATCGAGTGGGCC
CAGAACGGGGCGAGCCTCAGACTGGAGATCGACCCCGACCAGATCCGGTACATCCCGGCC
AATGTCGAGGCACAGATCAGCGCCACCACCGCATTCGGTGCCAAGTTCGTCGACCTGGTG
ATGCCGCAAAACCCAAGTCGTGCACGGCTGTCCGCTGGGGCGGTACTGCATTCGAAGAAC
GTCAGCACGGAAATCAACACCGTCTTCGAAAACGTCGTCGACCTGCTCAACATGATCGAC
CCGCTGAAACTGAACGCCGTGCTGACCGCGGTCGCCGACGCCGTTCGCGGGCAAGGTGAA
CGGATAGGCCAGGCCACCACCGACCTCAACGAGGTGCTGGAGGCACTCAACGCACGCGGC
GACACCATCGGCGGCAACTGGCGATCGCTCAAGAACTTCACCGACACCTATGACGCGGCC
GCCCAAGACATCCTGACGATCCTGAACGCCGCCAGCACCACCAGTGCGACCGTCGTGAAT
CATTCGACGCAGCTGGATGCCTTGCTACTCAACGCCATCGGACTATCCAACGCTGGCACC
AACCTGCTTGGCAGCAGCCGAGACAATCTCGTCGGCGCGGCCGACATCCTGGCGCCGACC
ACGAGCCTGCTGTTCAAGTACAACCCCGAATACACCTGCTTCCTGCAGGGCGCCAAGTGG
TATCTCGACAACGGCGGCTATGCGGCCTGGGGCGGGGCCGACGGGCGCACGCTACAACTC
GATGTGGCGCTACTGTTCGGCAACGACCCCTATGTCTATCCGGACAACCTGCCGGTTGTC
GCGGCCAAGGGGGGTCCCGGCGGAAGGCCGGGATGCGGGCCATTGCCGGATGCCACCCAC
AACTTCCCGGTGCGCCAGCTGGTCACCAACACCGGATGGGGAACCGGGCTGGACATCCGG
CCCAACCCCGGCATCGGGCATCCCTGCTGGGCCAACTACTTCCCGGTGACCCGCGCGGTG
CCCGAGCCGCCGTCGATCCGTCAGTGCATCCCCGGGCCGGCGATCGGGCCCAACCCCGCG
GCGGGGGAGCAGCCATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	ActivatedBy Rv1975	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression authors,MC. Garcia-Pelayo,KC. Caimi,JK. Inwald,J. Hinds,F. Bigi,MI. Romano,D. van Soolingen,RG. Hewinson,A. Cataldi,SV. Gordon Microarray analysis of Mycobacterium microti reveals deletion of genes encoding PE-PPE proteins and ESAT-6 family antigens. Tuberculosis (Edinb) 2004
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1968	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1968	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1968	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1968	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1968	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1963c	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1968	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1963c	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1968	active	sourish10	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1963c	active	sourish10	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1968	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1963c	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1968	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1963c	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1968	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1963c	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null