Rv1968 - MCE-family protein mce3C

Expression: Most Significant Conditions for Rv1968

Protein Domains

Gene Information
Locus	Rv1968
Symbol	mce3C
Gene Name	MCE-family protein mce3C
Location	2211626 - 2212858 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1233 bp Protein:411 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	22864
Related Genes	MAV_2534 MT2020 Mvan_0924
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1968
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1968 Transcript 1
MKSFAERNRLAIGTVGIVVVAAVALAALQYQRLPFFNQGTRVSAYFADAGGLRTGNTVEV
SGYPVGKVSSISLDGPGVLVEFKVDTDVRLGNRTEVAIKTKGLLGSKFLDVTPRGDGRLD
SPIPIERTTSPYQLPDALGDLAATISGLHTERLSESLATLAQTFADTPAHFRNAIHGVAR
LAQTLDERDNQLRSLLANAAKATGVLANRTDQIVGLVRDTNVVLAQLRTQSAALDRIWAN
ISAVAEQLRGFIAENRQQLRPALDKLNGVLAIVENRKERVRQAIPLINTYVMSLGESLSS
GPFFKAYVVNLLPGQFVQPFISAAFSDLGLDPATLLPSQLTDPPTGQPGTPPLPMPYPRT
GQGGEPRLTLPDAITGNPGDPRYPYRPEPPAPPPGGPPPGPPAQQPGDQP*

Genomic Sequence

>Rv1968
ATGAAATCCTTCGCCGAACGCAACCGTCTGGCCATCGGCACAGTCGGCATCGTCGTCGTC
GCCGCCGTTGCGCTGGCCGCGCTGCAATACCAGCGGCTGCCGTTTTTCAACCAGGGCACC
AGGGTCTCCGCCTATTTCGCCGACGCCGGCGGGCTGCGCACCGGCAACACCGTCGAGGTC
TCCGGCTATCCGGTGGGAAAAGTGTCCAGCATCTCGCTCGACGGACCGGGCGTGCTGGTG
GAGTTCAAGGTCGACACCGACGTCCGACTCGGAAACCGCACCGAAGTGGCAATCAAAACC
AAGGGCTTGTTGGGCAGCAAGTTCCTCGACGTCACCCCCCGCGGGGACGGCCGACTCGAT
TCTCCGATCCCGATCGAGCGGACCACGTCGCCCTACCAACTGCCCGACGCCCTTGGCGAT
TTGGCCGCCACGATCAGCGGGTTGCACACCGAGCGGCTGTCCGAATCGCTGGCCACCCTG
GCGCAGACCTTTGCCGATACGCCGGCGCACTTCCGCAACGCCATACACGGGGTGGCCCGG
CTCGCCCAAACCCTCGATGAGCGCGACAACCAACTGCGCAGCCTGCTGGCCAACGCGGCC
AAAGCCACCGGGGTGCTGGCCAACCGCACCGACCAGATCGTCGGCCTGGTGCGCGACACG
AATGTGGTCTTGGCGCAGCTGCGCACCCAAAGCGCCGCCCTGGACCGGATCTGGGCGAAC
ATCTCGGCGGTGGCCGAACAACTGCGGGGCTTCATCGCTGAGAACCGCCAGCAGCTGCGC
CCGGCGCTGGACAAGCTCAACGGGGTGCTGGCTATCGTCGAAAACCGCAAAGAGCGTGTG
CGGCAGGCCATCCCGCTGATCAACACCTATGTCATGTCGCTGGGTGAGTCGCTGTCGTCG
GGCCCGTTCTTCAAGGCATACGTGGTGAACCTGCTGCCGGGTCAGTTCGTGCAACCGTTC
ATCAGCGCCGCGTTCTCCGACCTGGGGCTCGACCCGGCCACGTTGCTGCCGTCGCAGCTG
ACCGACCCACCGACCGGTCAACCCGGAACCCCGCCGTTGCCGATGCCCTACCCGCGCACG
GGCCAGGGCGGTGAGCCGCGGCTGACGCTGCCCGACGCGATCACCGGCAATCCCGGCGAT
CCGCGCTATCCGTACCGGCCGGAGCCGCCCGCGCCGCCGCCCGGCGGGCCGCCGCCCGGC
CCGCCCGCGCAGCAGCCGGGAGACCAACCGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	ActivatedBy Rv1975	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression authors,MC. Garcia-Pelayo,KC. Caimi,JK. Inwald,J. Hinds,F. Bigi,MI. Romano,D. van Soolingen,RG. Hewinson,A. Cataldi,SV. Gordon Microarray analysis of Mycobacterium microti reveals deletion of genes encoding PE-PPE proteins and ESAT-6 family antigens. Tuberculosis (Edinb) 2004
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1966	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1963c	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1966	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1963c	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1966	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1963c	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1971	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1969	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1966	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1963c	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1967	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1966	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1966	active	sourish10	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1966	active	sourish10	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1966	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. The six mammalian cell entry proteins (Mce3A-F) encoded by the mce3 operon are expressed during in vitro growth of Mycobacterium tuberculosis. Scand. J. Immunol. 2005
Interaction	Regulatory Rv1966	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) S. Ahmad, S. El-Shazly et al. Mammalian cell-entry proteins encoded by the mce3 operon of Mycobacterium tuberculosis are expressed during natural infection in humans. Scand. J. Immunol. 2004
Interaction	Regulatory Rv1966	active	ahal4789	2012-10-05
	Coexpression(Functional linkage) D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null