Rv1998c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv1998c

Protein Domains

Gene Information
Locus	Rv1998c
Symbol
Gene Name	conserved hypothetical protein
Location	2242945 - 2243721 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:777 bp Protein:259 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	20154
Related Genes	CE1109 cg1206 MAP0296c MAP2254 MAV_0345 Mkms_0266 Mmcs_0256 MSMEG_0422 MSMEG_6646 MT2054 MUL_1177 Mvan_0289 nfa49070
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1998c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1998c Transcript 1
MSFHDLHHQGVPFVLPNAWDVPSALAYLAEGFTAIGTTSFGVSSSGGHPDGHRATRGANI
ALAAALAPLQCYVSVDIEDGYSDEPDAIADYVAQLSTAGINIEDSSAEKLIDPALAAAKI
VAIKQRNPEVFVNARVDTYWLRQHADTTSTIQRALRYVDAGADGVFVPLANDPDELAELT
RNIPCPVNTLPVPGLTIADLGELGVARVSTGSVPYSAGLYAAAHAARAVSDGEQLPRSVP
YAELQARLVDYENRTSTT*

Genomic Sequence

>Rv1998c
ATGAGTTTCCACGATCTTCATCACCAAGGTGTTCCGTTCGTGTTGCCCAACGCCTGGGAT
GTGCCGTCGGCCCTGGCCTACCTCGCGGAGGGCTTCACGGCTATCGGCACAACCAGTTTC
GGGGTCTCGTCCAGCGGCGGGCACCCGGACGGGCACCGCGCCACTCGCGGCGCCAACATC
GCACTGGCGGCCGCCCTGGCACCGCTGCAATGCTACGTCAGCGTCGACATCGAGGACGGA
TACAGCGACGAACCCGACGCCATTGCTGACTACGTCGCACAACTGTCGACAGCCGGAATC
AATATCGAGGACAGTAGCGCCGAAAAGCTCATCGACCCCGCCCTGGCAGCCGCTAAAATC
GTTGCGATCAAACAACGTAACCCCGAGGTGTTCGTCAACGCCCGCGTCGACACCTATTGG
TTGCGCCAGCACGCCGATACCACCAGCACGATCCAGCGCGCACTTCGCTACGTCGATGCC
GGCGCCGACGGCGTCTTTGTCCCACTGGCCAACGATCCCGACGAACTTGCTGAGCTCACT
CGCAACATTCCGTGCCCGGTTAACACGTTGCCCGTGCCCGGCTTGACGATCGCCGACCTT
GGTGAGCTCGGGGTGGCCCGGGTGTCAACCGGTTCAGTGCCCTACAGCGCGGGGTTGTAT
GCAGCGGCCCACGCGGCTCGGGCCGTGAGCGACGGAGAGCAGCTGCCACGGTCCGTACCG
TACGCCGAACTGCAGGCACGCTTGGTTGACTACGAGAACCGCACGAGTACAACGTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv0485	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. qRT-PCR. mRNA expression levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using qRT-PCR technique. RM. Goldstone, SD. Goonesekera et al. The transcriptional regulator Rv0485 modulates the expression of a pe and ppe gene pair and is required for Mycobacterium tuberculosis virulence. Infect. Immun. 2009
Interaction	RegulatedBy Rv0485	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. qRT-PCR. mRNA expression levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using qRT-PCR technique. RM. Goldstone, SD. Goonesekera et al. The transcriptional regulator Rv0485 modulates the expression of a pe and ppe gene pair and is required for Mycobacterium tuberculosis virulence. Infect. Immun. 2009