Rv2152c - UDP-N-acetylmuramate-alanine ligase murC

Expression: Most Significant Conditions for Rv2152c

Protein Domains

Gene Information
Locus	Rv2152c
Symbol	murC
Gene Name	UDP-N-acetylmuramate-alanine ligase murC
Location	2410638 - 2412122 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1485 bp Protein:495 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	34298
Related Genes	CE2052 cg2368 DIP1597 jk0751 MAP1896c MAV_2337 Mkms_3317 ML0915 Mmcs_3255 MSMEG_4226 MT2211 MUL_3500 Mvan_3522 nfa17670
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2152c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2152c Transcript 1
MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI
GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV
TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ
YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE
LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL
NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS
ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL
AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV
RANRSAPGRPGVLG*

Genomic Sequence

>Rv2152c
GTGAGCACCGAGCAGTTGCCGCCCGATCTGCGGCGGGTGCACATGGTCGGCATCGGCGGA
GCTGGCATGTCGGGCATCGCCCGAATCCTGCTGGACCGCGGCGGGCTGGTCTCCGGGTCA
GACGCCAAGGAGTCGCGCGGTGTGCATGCGCTGCGGGCGCGGGGCGCGTTGATCCGGATC
GGACACGACGCGTCGTCGCTGGACCTGTTGCCCGGTGGCGCCACGGCGGTCGTCACTACC
CATGCCGCCATCCCCAAAACCAACCCCGAGCTCGTCGAAGCGAGGCGCCGCGGCATTCCC
GTGGTGCTGCGGCCGGCCGTGCTGGCCAAGTTGATGGCCGGGCGCACCACATTGATGGTC
ACCGGCACGCACGGCAAGACAACGACGACGTCCATGCTGATCGTCGCCCTGCAGCACTGC
GGGCTTGACCCGTCCTTTGCGGTCGGCGGTGAGCTGGGGGAGGCCGGTACCAACGCCCAT
CACGGCAGTGGCGACTGTTTCGTCGCCGAAGCCGACGAAAGCGATGGCTCGCTGTTGCAG
TACACACCCCACGTCGCGGTGATCACCAACATCGAGTCCGATCACCTGGACTTCTACGGC
AGCGTCGAGGCGTATGTTGCGGTGTTCGACTCCTTCGTGGAGCGCATTGTCCCCGGGGGT
GCGCTGGTGGTGTGCACTGACGACCCCGGAGGGGCCGCGCTGGCTCAGCGCGCGACTGAG
CTGGGAATTCGAGTGCTGCGATACGGGTCGGTGCCGGGTGAGACCATGGCAGCCACGTTG
GTCTCGTGGCAGCAACAGGGGGTCGGCGCGGTCGCACATATCCGGTTGGCCTCAGAACTA
GCCACAGCACAGGGTCCCCGCGTGATGCGGCTGTCGGTGCCCGGGCGACACATGGCGCTC
AACGCGCTGGGAGCGCTGCTGGCCGCGGTGCAGATCGGCGCCCCGGCCGACGAGGTGCTC
GACGGGCTGGCCGGCTTCGAAGGAGTGCGGCGACGATTCGAACTGGTTGGGACCTGCGGC
GTCGGAAAGGCGTCGGTGCGCGTGTTCGATGACTACGCCCACCACCCGACGGAGATCAGC
GCGACACTGGCGGCGGCGCGCATGGTGCTCGAACAGGGCGACGGTGGCCGCTGCATGGTT
GTGTTTCAACCCCATTTGTATTCGCGGACAAAGGCATTCGCTGCTGAGTTTGGGCGTGCG
CTGAATGCCGCTGACGAGGTGTTCGTACTCGACGTCTACGGAGCTCGTGAACAACCGCTG
GCCGGTGTCAGCGGAGCCAGCGTCGCTGAGCACGTCACTGTGCCGATGCGCTACGTCCCG
GATTTTTCGGCGGTCGCACAGCAAGTGGCCGCCGCCGCTAGTCCGGGCGACGTCATCGTC
ACGATGGGTGCCGGAGACGTGACCTTGCTGGGCCCGGAAATCCTGACCGCCCTTCGGGTC
CGGGCCAACCGAAGCGCCCCCGGCCGTCCGGGGGTGCTGGGATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	UDP-N-acetylmuramate-alanine ligase	active	mjackson	2012-10-05
	Peptidoglycan precursor synthesis
Term	EC:6.3.2.8 UDP-N-acetylmuramate--L-alanine ligase. - NR	active	extern:JZUCKER	2012-03-06
	Inferred from direct assay authors,S. Mahapatra,H. Scherman,PJ. Brennan,DC. Crick N Glycolylation of the nucleotide precursors of peptidoglycan biosynthesis of Mycobacterium spp. is altered by drug treatment. J. Bacteriol. 2005
Term	EC:6.3.2.8 UDP-N-acetylmuramate--L-alanine ligase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,S. Mahapatra,H. Scherman,PJ. Brennan,DC. Crick N Glycolylation of the nucleotide precursors of peptidoglycan biosynthesis of Mycobacterium spp. is altered by drug treatment. J. Bacteriol. 2005