Rv2157c - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase murF

Expression: Most Significant Conditions for Rv2157c

Protein Domains

Gene Information
Locus	Rv2157c
Symbol	murF
Gene Name	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase murF
Location	2417472 - 2419004 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1533 bp Protein:511 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	34300
Related Genes	Acel_1006 CE2057 cg2373 DIP1602 jk0746 MAP1901c MAV_2332 Mkms_3322 ML0910 Mmcs_3260 MSMEG_4231 MT2216 MUL_3505 Mvan_3527 nfa17620 PPA0754 SAV6118
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2157c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2157c Transcript 1
MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH
AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV
AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR
TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH
SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE
VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD
AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS
RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD
VVLVKASNAAGLGAVADALVADDTCGSVRP*

Genomic Sequence

>Rv2157c
ATGATCGAGCTGACCGTCGCGCAGATCGCCGAGATCGTCGGGGGCGCAGTGGCCGATATC
TCCCCGCAAGACGCCGCGCACCGCCGCGTCACCGGGACCGTCGAGTTCGACTCGCGCGCC
ATCGGCCCGGGCGGGCTGTTCCTCGCCCTGCCGGGGGCGCGCGCCGACGGCCACGACCAT
GCCGCGTCGGCGGTAGCCGCGGGCGCCGCCGTCGTGCTGGCCGCCCGCCCGGTGGGGGTG
CCGGCCATCGTGGTTCCGCCAGTGGCCGCGCCGAACGTATTGGCCGGCGTCCTCGAGCAC
GACAACGACGGGTCGGGGGCGGCGGTGCTGGCCGCGCTGGCCAAGCTGGCCACCGCGGTG
GCCGCGCAGTTGGTGGCCGGCGGGCTCACCATCATCGGGATCACCGGCTCGTCGGGCAAG
ACGTCGACCAAGGACCTGATGGCCGCCGTGCTGGCCCCGCTGGGGGAGGTGGTGGCCCCG
CCCGGATCGTTCAACAACGAGCTGGGTCACCCGTGGACGGTGCTGCGCGCGACGCGGCGC
ACCGACTACCTGATTTTGGAGATGGCGGCACGCCATCACGGCAACATCGCCGCGCTCGCC
GAGATCGCGCCCCCGTCGATCGGAGTCGTGCTCAACGTCGGCACCGCACATTTGGGTGAG
TTCGGCTCCCGCGAGGTCATCGCACAGACCAAAGCCGAACTGCCGCAGGCTGTTCCGCAT
TCCGGAGCGGTCGTCCTCAACGCTGATGACCCCGCGGTGGCGGCGATGGCCAAGCTGACC
GCGGCCCGGGTGGTGCGGGTCAGCCGGGACAACACCGGTGACGTTTGGGCGGGGCCGGTG
TCGCTGGACGAATTGGCCAGGCCGCGCTTTACGCTGCATGCCCACGATGCCCAAGCCGAG
GTCCGACTCGGGGTCTGCGGCGACCACCAGGTCACTAACGCGCTGTGCGCCGCGGCGGTC
GCGCTGGAGTGTGGGGCCAGCGTTGAACAGGTCGCGGCCGCGCTGACCGCGGCGCCGCCG
GTGTCGCGGCATCGGATGCAGGTGACCACCCGCGGCGACGGGGTGACGGTGATCGACGAC
GCCTACAACGCCAACCCCGACTCCATGCGGGCCGGGCTGCAGGCGCTGGCCTGGATCGCG
CACCAACCCGAGGCCACCCGCCGCAGCTGGGCGGTGCTGGGTGAGATGGCCGAGCTGGGT
GAGGACGCGATAGCCGAGCACGATCGCATCGGCCGGCTCGCGGTGCGCTTAGATGTGTCT
CGACTCGTTGTCGTGGGAACCGGGAGGTCGATCAGCGCCATGCACCACGGAGCGGTCCTG
GAGGGGGCGTGGGGCTCGGGGGAAGCCACTGCTGATCACGGTGCGGATCGCACGGCCGTC
AATGTGGCCGACGGTGACGCCGCCCTGGCACTACTGCGCGCCGAGCTGCGACCCGGGGAT
GTGGTCTTGGTCAAGGCCTCGAACGCGGCCGGGCTGGGTGCGGTGGCCGATGCATTGGTC
GCAGACGACACATGCGGGAGTGTGCGCCCATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase	active	mjackson	2012-10-05
	Peptidoglycan precursor synthesis