Rv2210c - branched-chain amino acid transaminase ilvE

Expression: Most Significant Conditions for Rv2210c

Protein Domains

Gene Information
Locus	Rv2210c
Symbol	ilvE
Gene Name	branched-chain amino acid transaminase ilvE
Location	2474864 - 2475970 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1107 bp Protein:369 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32924
Related Genes	Acel_0711 CE2095 cg2418 DIP1636 jk0710 MAP1950c MAV_2281 Mkms_3370 ML0866 Mmcs_3308 MSMEG_4276 MT2266 MUL_3570 Mvan_3573 Mvan_4516 nfa16970 nfa3220 PPA1368 SAV2717 SAV6804 SCO5523
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2210c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2210c Transcript 1
MTSGSLQFTVLRAVNPATDAQRESMLREPGFGKYHTDHMVSIDYAEGRGWHNARVIPYGP
IELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRADANAARLRSSARRLAIPELPDAVFI
ESLRQLIAVDKAWVPGAGGEEALYLRPFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG
IAPVSVWVSTEYVRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEE
MGGMNIFFVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRIDIDEWQKK
AAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVTMALRDTLTGIQRGTFADT
HGWMARLG*

Genomic Sequence

>Rv2210c
ATGACCAGCGGCTCCCTTCAATTCACGGTGTTACGTGCGGTCAATCCGGCCACCGACGCG
CAGCGTGAATCGATGCTGCGGGAGCCGGGTTTCGGCAAATACCACACCGACCATATGGTG
TCGATCGACTATGCCGAGGGCCGTGGTTGGCACAACGCGCGGGTAATCCCTTATGGCCCG
ATCGAGCTGGATCCCTCGGCGATCGTGCTGCACTATGCGCAGGAGGTGTTCGAAGGGCTC
AAAGCCTACCGCTGGGCCGACGGGTCCATCGTGTCGTTTCGCGCCGACGCCAACGCCGCC
AGGTTGCGTTCGTCGGCGCGGCGGTTGGCGATTCCCGAACTGCCCGACGCGGTGTTCATC
GAATCCCTGCGCCAGCTAATCGCTGTCGACAAAGCTTGGGTGCCCGGTGCCGGCGGTGAG
GAGGCGCTGTATCTGCGGCCGTTCATCTTCGCCACCGAGCCGGGACTGGGCGTGCGGCCT
GCCACCCAATACCGTTACCTGTTGATCGCCTCGCCGGCCGGTGCGTACTTCAAGGGCGGC
ATCGCCCCTGTCAGCGTCTGGGTTTCGACGGAGTATGTACGGGCCTGTCCGGGCGGCACC
GGTGCGGCCAAGTTCGGCGGCAACTACGCCGCCTCGTTGCTGGCGCAGGCCGAAGCCGCC
GAGAACGGATGCGACCAGGTGGTGTGGCTGGACGCTGTGGAACGCCGCTATATCGAAGAG
ATGGGTGGCATGAACATCTTCTTCGTGCTCGGCAGCGGCGGATCGGCGCGGCTGGTCACC
CCGGAGCTGTCCGGTTCCCTGCTGCCCGGGATCACACGGGATTCGTTGTTGCAGTTGGCT
ATTGATGCCGGATTCGCGGTCGAGGAACGCAGGATTGATATCGACGAGTGGCAGAAGAAA
GCCGCCGCCGGCGAGATCACCGAGGTGTTTGCGTGCGGCACCGCCGCTGTCATCACCCCG
GTCGCGCGGGTGCGGCACGGTGCCAGCGAGTTCAGAATCGCCGACGGTCAGCCGGGTGAG
GTGACCATGGCACTACGCGATACGCTGACCGGCATCCAGCGGGGCACCTTCGCGGACACC
CACGGCTGGATGGCGCGGCTGGGGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Term	EC:2.6.1.42 Branched-chain-amino-acid transaminase. - NR	active	extern:JZUCKER	2012-03-06
	Inferred from mutant phenotype LW. Tremblay & JS. Blanchard The 1.9 A structure of the branched-chain amino-acid transaminase (IlvE) from Mycobacterium tuberculosis. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2009
Term	EC:2.6.1.42 Branched-chain-amino-acid transaminase. - NR	active	extern:JZUCKER	2012-03-06
	Traceable author statement to experimental support authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011