Rv2243 - malonyl CoA-acyl carrier protein transacylase fabD

Expression: Most Significant Conditions for Rv2243

Protein Domains

Gene Information
Locus	Rv2243
Symbol	fabD
Gene Name	malonyl CoA-acyl carrier protein transacylase fabD
Location	2516787 - 2517695 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:909 bp Protein:303 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	31819
Related Genes	MAP1996 MAV_2194 Mkms_3426 ML1653 Mmcs_3364 MSMEG_4325 MT2303 MUL_1306 Mvan_3754 nfa16150
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2243
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2243 Transcript 1
MIALLAPGQGSQTEGMLSPWLQLPGAADQIAAWSKAADLDLARLGTTASTEEITDTAVAQ
PLIVAATLLAHQELARRCVLAGKDVIVAGHSVGEIAAYAIAGVIAADDAVALAATRGAEM
AKACATEPTGMSAVLGGDETEVLSRLEQLDLVPANRNAAGQIVAAGRLTALEKLAEDPPA
KARVRALGVAGAFHTEFMAPALDGFAAAAANIATADPTATLLSNRDGKPVTSAAAAMDTL
VSQLTQPVRWDLCTATLREHTVTAIVEFPPAGTLSGIAKRELRGVPARAVKSPADLDELA
NL*

Genomic Sequence

>Rv2243
GTGATTGCGTTGCTCGCACCCGGACAGGGTTCGCAAACCGAGGGAATGTTGTCGCCGTGG
CTTCAGCTGCCCGGCGCAGCGGACCAGATCGCGGCGTGGTCGAAAGCCGCTGATCTAGAT
CTTGCCCGGCTGGGCACCACCGCCTCGACCGAGGAGATCACCGACACCGCGGTCGCCCAG
CCATTGATCGTCGCCGCGACTCTGCTGGCCCACCAGGAACTGGCGCGCCGATGCGTGCTC
GCCGGCAAGGACGTCATCGTGGCCGGCCACTCCGTCGGCGAAATCGCGGCCTACGCAATC
GCCGGTGTGATAGCCGCCGACGACGCCGTCGCGCTGGCCGCCACCCGCGGCGCCGAGATG
GCCAAGGCCTGCGCCACCGAGCCGACCGGCATGTCTGCGGTGCTCGGCGGCGACGAGACC
GAGGTGCTGAGTCGCCTCGAGCAGCTCGACTTGGTCCCGGCAAACCGCAACGCCGCCGGC
CAGATCGTCGCTGCCGGCCGGCTGACCGCGTTGGAGAAGCTCGCCGAAGACCCGCCGGCC
AAGGCGCGGGTGCGTGCACTGGGTGTCGCCGGAGCGTTCCACACCGAGTTCATGGCGCCC
GCACTTGACGGCTTTGCGGCGGCCGCGGCCAACATCGCAACCGCCGACCCCACCGCCACG
CTGCTGTCCAACCGCGACGGGAAGCCGGTGACATCCGCGGCCGCGGCGATGGACACCCTG
GTCTCCCAGCTCACCCAACCGGTGCGATGGGACCTGTGCACCGCGACGCTGCGCGAACAC
ACAGTCACGGCGATCGTGGAGTTCCCCCCCGCGGGCACGCTTAGCGGTATCGCCAAACGC
GAACTTCGGGGGGTTCCGGCACGCGCCGTCAAGTCACCCGCAGACCTGGACGAGCTGGCA
AACCTATAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv2111c	active	priyadarshinipriyanka2001	2012-10-05
	Affinity purification (Physical interaction) MJ. Pearce, J. Mintseris et al. Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis. Science 2008
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
Name	MALONYL CoA-ACYL CARRIER PROTEIN TRANSACYLASE	active	mjackson	2012-10-05
	FAS-I->FAS-II
Name	MALONYL CoA-ACYL CARRIER PROTEIN TRANSACYLASE	active	mjackson	2012-10-05
	FAS-I->FAS-II
Term	EC:2.3.1.39 [Acyl-carrier-protein] S-malonyltransferase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
Term	EC:2.3.1.38 [Acyl-carrier-protein] S-acetyltransferase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
Term	EC:6.4.1.2 Acetyl-CoA carboxylase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005