Rv2335 - serine acetyltransferase cysE


Protein Domains

Gene Information
LocusRv2335
SymbolcysE
Gene Nameserine acetyltransferase cysE
Location2609732 - 2610421 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:690 bp
Protein:230 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number33686
Related GenesAcel_1935 Acel_1940 CE2447 cg0439 cg2834 DIP1891 jk0393 MAP2124 MAV_2051 Mkms_0957 ML0838 Mmcs_0940 MSMEG_5947 MSMEG_5950 MT2398 MUL_1464
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv2335
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionInhibitedBy Rv2334activeakankshajain.212012-10-05
Functional Linkage(Coexpression)
D. Gren, R. Schnell et al. The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity. FEBS Lett. 2008
InteractionInhibitedBy Rv2334activeakankshajain.212012-10-05
Structural Analysis
D. Gren, R. Schnell et al. The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity. FEBS Lett. 2008
InteractionInhibitedBy Rv2334activeakankshajain.212012-10-05
Structural Analysis
R. Schnell, W. Oehlmann et al. Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex. J. Biol. Chem. 2007
InteractionInhibitedBy Rv2334activeakankshajain.212012-10-05
Spectrophotometric Assay
D. Gren, R. Schnell et al. The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity. FEBS Lett. 2008
InteractionInhibitedBy Rv2334activeakankshajain.212012-10-05
Spectrophotometric Assay
R. Schnell, W. Oehlmann et al. Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex. J. Biol. Chem. 2007
TermEC:2.3.1.30 Serine O-acetyltransferase. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
authors,DA. Hodgson Primary metabolism and its control in streptomycetes: a most unusual group of bacteria. Adv. Microb. Physiol. 2000