Rv2351c - membrane-associated phospholipase C 1 plcA

Expression: Most Significant Conditions for Rv2351c

Protein Domains

Gene Information
Locus	Rv2351c
Symbol	plcA
Gene Name	membrane-associated phospholipase C 1 plcA
Location	2630537 - 2632075 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1539 bp Protein:513 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	18919
Related Genes	MT2414 MT2415 MT2416 Rv2349c Rv2350c SAV1715
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2351c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2351c Transcript 1
MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF
GTLSSTNGFNAASPAFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWV
GMHLAWNGGANDNWLPAQATTRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLL
TGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKG
LGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNI
LQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTP
GEFVTVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRARF
GVPVPNMTAWRDGVVGDMTSAFNFATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDG
ALPSIPYRVPYPQVMPTQETTPVRGTPSGLCS*

Genomic Sequence

>Rv2351c
ATGTCACGTCGAGAGTTTTTGACAAAGCTCACTGGCGCAGGCGCAGCGGCATTCCTGATG
GACTGGGCTGCACCGGTGATTGAAAAGGCCTACGGCGCCGGGCCTTGTCCCGGACATTTG
ACCGACATCGAGCATATCGTGTTGCTGATGCAGGAGAACCGGTCATTCGACCACTATTTC
GGAACGCTTTCCAGCACCAATGGGTTCAACGCCGCGTCGCCGGCATTCCAACAAATGGGT
TGGAACCCCATGACGCAGGCGTTGGACCCCGCCGGGGTCACCATTCCGTTCCGCTTGGAC
ACCACCCGAGGCCCCTTCCTGGACGGCGAGTGCGTCAACGACCCCGAGCACCAGTGGGTG
GGGATGCACCTGGCCTGGAACGGTGGTGCCAACGACAACTGGCTGCCGGCGCAGGCGACC
ACCCGCGCAGGACCATATGTCCCTTTGACCATGGGTTACTACACGCGCCAAGACATCCCG
ATCCACTATCTGCTGGCCGACACGTTCACCATCTGCGACGGCTACCATTGCTCGCTGCTG
ACGGGCACCCTGCCCAACCGGCTCTACTGGTTGAGCGCCAACATCGACCCCGCCGGCACC
GACGGGGGACCCCAATTGGTAGAGCCGGGCTTCCTGCCGCTGCAGCAATTCAGTTGGCGC
ATCATGCCGGAAAACCTCGAAGATGCCGGGGTCAGCTGGAAGGTGTACCAGAACAAGGGC
CTCGGGCGATTCATCAACACGCCCATCAGCAATAACGGGCTGGTGCAGGCCTTCCGCCAG
GCAGCTGATCCGAGGTCGAACTTGGCCCGCTACGGTATCGCCCCGACCTACCCTGGGGAC
TTCGCTGCCGACGTCAGGGCCAACCGGCTACCCAAGGTCTCCTGGTTAGTTCCCAACATC
CTGCAGTCCGAACACCCCGCCCTGCCGGTAGCGCTTGGCGCGGTGTCCATGGTGACCGCG
CTGCGGATCTTGCTGTCCAATCCCGCGGTGTGGGAAAAGACCGCACTTATCGTCAGCTAT
GACGAGAACGGCGGCTTCTTCGACCACGTCACGCCCCCCACGGCACCGCCCGGGACACCC
GGCGAATTCGTCACGGTGCCCAACATCGACGCAGTACCCGGGTCCGGTGGCATTCGTGGT
CCGCTCGGTCTGGGTTTTCGCGTTCCCTGCATTGTCATTTCGCCGTACAGCCGCGGCCCG
CTGATGGTCTCCGACACGTTCGACCACACCTCGCAATTGAAGTTGATTCGCGCCCGGTTC
GGCGTGCCGGTTCCCAACATGACCGCCTGGCGCGACGGCGTGGTTGGCGACATGACCTCA
GCGTTCAACTTTGCGACTCCACCGAATTCGACCAGACCCAACTTGAGCCACCCGTTGCTG
GGAGCGCTGCCGAAGCTGCCGCAGTGCATCCCTAACGTGGTGTTGGGAACCACCGACGGC
GCGTTGCCGAGCATTCCCTATCGGGTGCCCTATCCGCAGGTGATGCCAACTCAGGAAACC
ACACCCGTCCGCGGGACTCCCAGCGGGCTGTGCAGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Symbol	PlcA	active	jlew	2012-03-07
	Contains a functional tat sequence. Test for functional tat sequences using a BlaC reporter. 13 identified. JA. McDonough, JR. McCann et al. Identification of functional Tat signal sequences in Mycobacterium tuberculosis proteins. J. Bacteriol. 2008