Rv2443 - C4-dicarboxylate-transport transmembrane protein dctA

Expression: Most Significant Conditions for Rv2443

Protein Domains

Gene Information
Locus	Rv2443
Symbol	dctA
Gene Name	C4-dicarboxylate-transport transmembrane protein dctA
Location	2740709 - 2742184 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1476 bp Protein:492 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	19582
Related Genes	cg2870 jk1314 Mkms_4242 Mmcs_4176 MSMEG_5302 MT2519 Mvan_4696 nfa46330 SAV2815
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2443
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2443 Transcript 1
MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKSLTVLGTVFVN
LIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFLTMSSVALGIGLIVGNLLSPGR
DLHLRPGAVGSGAALAGQAAESHGIAGFIQQIIPRSLPSALTEGNVLQVLLVALLVGFAV
QGLGPAGESILRAVENLQKLVFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMA
GFYLTCVVFVFGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLITKMKHL
GVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGEQIALLAFMIIASKGA
AGVSGAGLATLAGGLQAHRPELLDGVGLIVGIDRFMSEARSLTNFSGNAVATILVASWTK
TIDLSKADEVLRGRDPFDESTMVDPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGR
PAGPQRADVDG*

Genomic Sequence

>Rv2443
ATGACCGCCCCCTTGGATCGTGCGCCGGTCACGGATTTGCCGGCTAACAACAAAGGCCGA
GACCGCACCCACTGGCTGTATCTCGCGGTCATTTTCGCAGTGATAGCCGGTGTGATCGTG
GGGCTGACGGCGCCGTCGACCGGAAAAAGCCTCACGGTGCTCGGGACGGTGTTCGTCAAC
CTGATCAAGATGATGATCGCACCGGTCATCTTCTGCACGATCGTGCTCGGGATCGGCTCG
GTGCGCAAAGCCGCGGCCGTGGGCAAGGTCGGCGGGCTGGCTTTGGCCTACTTTCTAACG
ATGTCATCGGTGGCGCTCGGGATCGGGTTGATCGTCGGCAACCTACTCAGTCCGGGTAGG
GATCTGCACCTTAGGCCTGGTGCGGTCGGAAGCGGCGCAGCATTGGCCGGCCAGGCTGCG
GAGTCACACGGAATCGCTGGGTTCATCCAGCAGATCATTCCGAGGTCGCTCCCCTCAGCC
CTTACTGAAGGCAACGTGCTGCAGGTGTTACTCGTCGCGCTGCTGGTCGGTTTCGCGGTC
CAAGGCCTGGGCCCCGCAGGCGAGTCCATCCTGCGTGCCGTCGAGAACCTGCAAAAGCTG
GTGTTCAAGGTGCTCGTGATGGTACTGTGGCTGGCTCCGATCGGCGCGTTCGGTGCGATC
GCCAATATCGTCGCCACGACTGGCTTCAACGCCGTCACCAACCTGCTGCTGCTGATGGCC
GGCTTCTACCTGACGTGCGTGGTGTTCGTTTTCGGCGTCCTGGGAGTGCTACTGCGCATC
GTGTCGGGTTTGTCGATCTTTCGGCTGCTGCGCTATCTAGCCCGCGAGTACTTGCTGATC
TTCGCAACATCGTCGTCGGAGGTGGTGCTGCCCAGACTGATCACCAAGATGAAACACTTG
GGCGTGCAATCCAGCACGGTCGGCGTGGTGGTGCCGACCGGCTACTCGTTCAATCTTGAC
GGCACCGCTATCTATCTGACCATGGCGTCGCTGTTCATCGCCGACGCGATGGGACATCGC
TTGACATGGGGCGAGCAGATCGCGCTGCTGGCGTTCATGATCATCGCGTCCAAGGGCGCT
GCCGGGGTCAGCGGTGCGGGCCTTGCGACGCTGGCCGGCGGCCTGCAGGCTCATCGCCCC
GAGCTGCTGGACGGTGTCGGGCTGATTGTGGGGATCGACCGGTTCATGTCGGAAGCCCGT
TCGCTCACGAACTTCTCCGGCAACGCCGTCGCAACCATCCTGGTTGCCTCGTGGACAAAG
ACCATTGACCTGTCCAAAGCCGACGAGGTGTTGCGCGGTCGTGATCCCTTCGACGAATCG
ACCATGGTCGATCCCCACGATGAGGAGCCACCCGCCGCCACACCCCACGGGGGCGGCGTC
CCGACGAACCCTGCGCTGTGCGATTTCGAGCAGGTCAGTCTAGGCGGATTGGTGGGCCGG
CCGGCCGGCCCGCAACGCGCCGACGTGGACGGGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006