Rv2464c - DNA glycosylase

Expression: Most Significant Conditions for Rv2464c

Protein Domains

Gene Information
Locus	Rv2464c
Symbol
Gene Name	DNA glycosylase
Location	2766859 - 2767665 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:807 bp Protein:269 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	29023
Related Genes	CE2834 cg3328 DIP2304 MAP2284c MAV_1708 Mkms_3671 Mmcs_3598 MSMEG_4683 MT2539 MUL_3737 Mvan_4051 nfa13280 PPA1623 SAV5427
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2464c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2464c Transcript 1
MPEGHTLHRLARLHQRRFAGAPVSVSSPQGRFADSASALNGRVLRRASAWGKHLFHHYVG
GPVVHVHLGLYGTFTEWARPTDGWLPEPAGQVRMRMVGAEFGTDLRGPTVCESIDDGEVA
DVVARLGPDPLRSDANPSSAWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDP
QRPGRGIGEPEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRAG
EPCRVCGGVIRTALLEGRNVFWCPVCQT*

Genomic Sequence

>Rv2464c
GTGCCTGAGGGGCATACGCTGCATCGGCTGGCCCGGCTGCACCAGCGCCGGTTCGCCGGT
GCGCCGGTCTCGGTGTCCAGCCCCCAGGGCCGGTTCGCCGATTCGGCTTCCGCGCTCAAC
GGTCGGGTGTTGCGGCGGGCCAGTGCCTGGGGCAAACACCTGTTCCATCACTACGTCGGC
GGCCCCGTGGTGCACGTGCATCTCGGGCTCTATGGCACCTTCACCGAATGGGCACGCCCC
ACAGATGGGTGGCTACCCGAACCCGCGGGGCAGGTGCGGATGCGGATGGTCGGGGCAGAA
TTCGGCACCGACTTGCGCGGCCCGACGGTGTGTGAGTCGATCGACGACGGCGAGGTTGCG
GACGTGGTTGCCAGGCTGGGACCCGACCCGTTGCGTAGCGACGCCAACCCGTCGTCGGCA
TGGTCTCGGATCACCAAGTCTCGCAGGCCCATAGGCGCGCTCTTGATGGACCAAACGGTG
ATCGCCGGTGTTGGCAACGTCTACCGTAATGAGTTGCTTTTTCGGCACCGGATCGACCCA
CAGCGGCCCGGCCGCGGGATCGGTGAGCCGGAATTCGACGCGGCCTGGAACGATCTGGTG
TCGTTGATGAAGGTGGGCTTGCGCCGCGGCAAGATCATCGTGGTGCGCCCCGAACATGAC
CATGGTCTGCCGTCATATCTGCCCGACCGGCCCCGCACCTATGTGTACCGCCGAGCCGGC
GAGCCGTGTCGGGTGTGTGGGGGAGTGATCCGCACGGCACTGCTCGAGGGCCGCAATGTT
TTCTGGTGCCCGGTCTGTCAGACCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Other	TBPWY:Base excision repair (BER)	active	vmizrahi	2012-03-05
	Over-expressed and purified. Nei1 excises thymine glycol (Tg) and strongly prefers the (5R) isomers. hen expressed in E. coli, it decreased the spontaneous mutation frequency of both the fpg mutY nei triple and nei nth double mutants, suggesting that Nei2 is functionally active in vivo recognizing both guanine and cytosine oxidation products
Symbol	nei1	active	vmizrahi	2012-03-05
	Over-expressed and purified. Nei1 excises thymine glycol (Tg) and strongly prefers the (5R) isomers. hen expressed in E. coli, it decreased the spontaneous mutation frequency of both the fpg mutY nei triple and nei nth double mutants, suggesting that Nei2 is functionally active in vivo recognizing both guanine and cytosine oxidation products