Rv2878c - soluble secreted antigen mpt53 precursor

Expression: Most Significant Conditions for Rv2878c

Protein Domains

Gene Information
Locus	Rv2878c
Symbol	mpt53
Gene Name	soluble secreted antigen mpt53 precursor
Location	3188876 - 3189397 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:522 bp Protein:174 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	30141
Related Genes	MAP2942c MAV_3729 MSMEG_3543 MT2946 MUL_2079
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2878c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2878c Transcript 1
MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQ
GKPAVLWFWTPWCPFCNAEAPSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTN
LNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMSQDELSGRVAALTS*

Genomic Sequence

>Rv2878c
ATGAGTCTTCGCCTGGTGTCCCCGATCAAGGCGTTTGCGGACGGCATTGTGGCCGTTGCT
ATCGCGGTTGTCCTGATGTTCGGTCTGGCCAATACACCGCGAGCGGTGGCAGCCGATGAA
CGTCTGCAGTTCACCGCAACCACGCTCAGCGGTGCTCCCTTCGATGGCGCAAGCCTGCAA
GGCAAGCCGGCGGTGTTGTGGTTCTGGACGCCGTGGTGCCCGTTCTGCAACGCAGAAGCC
CCCAGCCTCAGCCAGGTAGCGGCCGCTAATCCGGCGGTCACCTTCGTCGGAATCGCCACC
CGCGCCGACGTCGGGGCGATGCAGAGCTTTGTCTCGAAGTACAACCTGAATTTCACCAAC
CTCAATGACGCCGATGGTGTGATCTGGGCCCGCTACAACGTGCCTTGGCAACCGGCATTT
GTGTTCTATCGCGCGGACGGCACATCGACGTTCGTCAACAACCCCACCGCGGCCATGTCT
CAGGACGAGCTGTCCGGCCGGGTGGCTGCGCTGACGTCCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv0735	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
Interaction	PhysicalInteraction Rv2877c	active	priti.priety	2012-10-05
	Gene Neighborhood (Functional linkage) MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
Interaction	PhysicalInteraction Rv2877c	active	priti.priety	2012-10-05
	Gene Neighborhood (Functional linkage) MY. Hahn, S. Raman et al. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J. Bacteriol. 2005
Interaction	RegulatedBy Rv0735	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008