Rv2916c - signal recognition particle protein ffh

Expression: Most Significant Conditions for Rv2916c

Protein Domains

Gene Information
Locus	Rv2916c
Symbol	ffh
Gene Name	signal recognition particle protein ffh
Location	3224708 - 3226285 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1578 bp Protein:526 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	34039
Related Genes	Acel_1563 CE1965 cg2257 DIP1533 jk1195 MAP2983c MAV_3770 Mkms_2005 ML1622 Mmcs_1959 MSMEG_2430 MT2984 MUL_2040 Mvan_2181 nfa41600 PPA1445 SAV2648 SCO5586
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2916c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2916c Transcript 1
MFESLSDRLTAALQGLRGKGRLTDADIDATTREIRLALLEADVSLPVVRAFIHRIKERAR
GAEVSSALNPAQQVVKIVNEELISILGGETRELAFAKTPPTVVMLAGLQGSGKTTLAGKL
AARLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFAPHPGASPESGPGDPVAVAAA
GLAEARAKHFDVVIVDTAGRLGIDEELMAQAAAIRDAINPDEVLFVLDAMIGQDAVTTAA
AFGEGVGFTGVALTKLDGDARGGAALSVREVTGVPILFASTGEKLEDFDVFHPDRMASRI
LGMGDVLSLIEQAEQVFDAQQAEEAAAKIGAGELTLEDFLEQMLAVRKMGPIGNLLGMLP
GAAQMKDALAEVDDKQLDRVQAIIRGMTPQERADPKIINASRRLRIANGSGVTVSEVNQL
VERFFEARKMMSSMLGGMGIPGIGRKSATRKSKGAKGKSGKKSKKGTRGPTPPKVKSPFG
VPGMPGLAGLPGGLPDLSQMPKGLDELPPGLADFDLSKLKFPGKK*

Genomic Sequence

>Rv2916c
GTGTTTGAATCGCTGTCTGACCGTTTGACCGCCGCCCTGCAGGGGCTGCGCGGCAAGGGC
CGACTGACCGATGCCGATATCGATGCCACTACCCGCGAAATTCGTTTGGCGCTGCTGGAA
GCCGATGTTTCGCTACCGGTGGTCCGGGCATTCATCCACCGGATCAAAGAACGCGCCCGC
GGGGCCGAGGTGTCAAGTGCCCTCAACCCGGCTCAACAGGTCGTCAAGATCGTCAACGAG
GAACTGATAAGCATCCTCGGCGGCGAAACCCGCGAGTTGGCGTTTGCGAAGACCCCGCCG
ACCGTCGTGATGCTCGCCGGCCTGCAGGGCTCCGGGAAGACGACACTGGCCGGCAAATTG
GCCGCCCGCCTGCGTGGACAAGGACACACGCCACTGCTGGTCGCTTGTGACCTGCAACGG
CCGGCCGCGGTGAACCAGCTGCAGGTCGTCGGCGAGCGTGCCGGAGTGCCGGTGTTCGCG
CCGCATCCGGGTGCCTCGCCGGAGTCCGGCCCCGGTGACCCGGTTGCGGTGGCGGCGGCC
GGGCTGGCCGAGGCCCGGGCCAAGCACTTCGACGTCGTCATCGTCGACACCGCCGGACGA
CTGGGCATCGACGAGGAGCTGATGGCCCAGGCCGCGGCCATCCGCGACGCCATCAACCCC
GACGAGGTGCTGTTCGTCCTGGACGCGATGATCGGCCAGGACGCGGTCACCACCGCTGCG
GCGTTCGGCGAGGGCGTCGGGTTCACCGGTGTGGCCTTGACCAAGCTCGACGGTGACGCC
CGCGGTGGTGCCGCGTTATCGGTGCGCGAAGTGACCGGTGTTCCAATCCTTTTCGCCTCC
ACCGGGGAGAAGCTGGAGGACTTCGACGTCTTCCACCCGGACCGGATGGCCAGTCGCATC
TTGGGCATGGGCGATGTGCTGAGCCTGATCGAACAGGCCGAGCAGGTCTTCGATGCACAA
CAGGCCGAGGAGGCCGCAGCCAAGATCGGCGCCGGCGAGCTGACCCTGGAGGACTTCCTC
GAGCAGATGCTCGCGGTACGCAAGATGGGCCCGATCGGCAACCTGCTGGGCATGCTGCCC
GGCGCGGCTCAGATGAAGGACGCGTTGGCCGAGGTCGACGACAAACAACTCGATCGTGTC
CAGGCCATCATTCGCGGCATGACGCCGCAGGAACGGGCAGACCCCAAGATCATCAATGCC
TCGCGGCGGCTGCGCATCGCCAACGGCTCGGGCGTCACGGTGTCCGAGGTCAACCAGCTG
GTCGAGCGCTTCTTCGAAGCCCGCAAGATGATGTCGTCCATGCTCGGGGGCATGGGCATA
CCGGGCATAGGGCGCAAATCCGCGACGCGAAAGAGCAAGGGCGCAAAAGGCAAATCCGGC
AAGAAGAGTAAGAAGGGGACGCGCGGTCCGACGCCGCCGAAGGTCAAGAGCCCGTTCGGC
GTGCCCGGGATGCCGGGCTTGGCTGGGCTACCTGGGGGGCTCCCTGATCTCTCACAGATG
CCCAAAGGTCTCGACGAGCTGCCGCCCGGCCTGGCCGACTTCGACCTGTCCAAGCTGAAG
TTCCCAGGCAAGAAGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Activation Rv2921c	active	shahanup86	2012-10-05
	Co-occurrence (Functional linkage) authors,J. Luirink,CM. ten Hagen-Jongman,CC. van der Weijden,B. Oudega,S. High,B. Dobberstein,R. Kusters An alternative protein targeting pathway in Escherichia coli: studies on the role of FtsY. EMBO J. 1994
Interaction	Activation Rv2921c	active	shahanup86	2012-10-05
	Co-occurrence (Functional linkage) Y. Av-Gay,M. Everett The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. Trends Microbiol. 2000
Interaction	Signaling Rv2914c	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) A. Singh, Y. Singh et al. Protein kinase I of Mycobacterium tuberculosis: cellular localization and expression during infection of macrophage-like cells. Tuberculosis (Edinburgh, Scotland) 2006
Interaction	Signaling Rv2914c	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Gopalaswamy, S. Narayanan et al. The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. FEMS Microbiol. Lett. 2009
Interaction	Signaling Rv2914c	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Gopalaswamy, PR. Narayanan et al. Cloning, overexpression, and characterization of a serine/threonine protein kinase pknI from Mycobacterium tuberculosis H37Rv. Protein Expr. Purif. 2004
Interaction	Operon Rv2913c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) R. Gopalaswamy, S. Narayanan et al. The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. FEMS Microbiol. Lett. 2009
Interaction	Operon Rv2913c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) Y. Av-Gay,M. Everett The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. Trends Microbiol. 2000
Interaction	Operon Rv2913c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) authors,A. Zelikovski,J. Abu-Dalu,I. Urca Meso-appendicular testis. Br J Urol 1975
Interaction	Operon Rv2913c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) authors,BM. Altura Role of prostaglandins and histamine in reactive hyperemia: in-vivo studies on single mesenteric arterioles. Prostaglandins Med 1978