Rv2976c - uracil-DNA glycosylase ung

Expression: Most Significant Conditions for Rv2976c

Protein Domains

Gene Information
Locus	Rv2976c
Symbol	ung
Gene Name	uracil-DNA glycosylase ung
Location	3332071 - 3332754 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:684 bp Protein:228 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32644
Related Genes	CE1436 cg1496 DIP1134 jk1214 MAP3016c MAV_3828 Mkms_1979 ML1675 Mmcs_1933 MSMEG_2399 MT3053 MUL_1980 Mvan_2152 nfa42000 PPA0558 SAV7011
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2976c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2976c Transcript 1
MTARPLSELVERGWAAALEPVADQVAHMGQFLRAEIAAGRRYLPAGSNVLRAFTFPFDNV
RVLIVGQDPYPTPGHAVGLSFSVAPDVRPWPRSLANIFDEYTADLGYPLPSNGDLTPWAQ
RGVLLLNRVLTVRPSNPASHRGKGWEAVTECAIRALAARAAPLVAILWGRDASTLKPMLA
AGNCVAIESPHPSPLSASRGFFGSRPFSRANELLVGMGAEPIDWRLP*

Genomic Sequence

>Rv2976c
GTGACCGCACGGCCGTTGAGTGAGCTCGTCGAGCGGGGGTGGGCCGCCGCGCTCGAGCCG
GTGGCCGACCAGGTGGCCCACATGGGGCAGTTCTTGCGGGCCGAGATCGCGGCCGGGCGC
AGATACCTGCCCGCCGGATCGAATGTGTTGCGCGCCTTCACTTTCCCGTTCGACAACGTC
CGTGTCCTTATCGTTGGCCAAGACCCTTATCCGACTCCAGGACATGCTGTGGGTCTTAGC
TTCTCGGTGGCCCCTGATGTACGTCCGTGGCCGCGCAGTCTGGCCAACATCTTCGACGAG
TACACCGCGGATTTGGGCTATCCGCTGCCCTCGAACGGCGATCTGACGCCCTGGGCGCAA
CGCGGTGTGTTGCTGTTGAACAGGGTGCTGACGGTGCGACCCAGCAACCCGGCGTCGCAC
CGGGGCAAGGGCTGGGAAGCGGTCACGGAATGCGCGATTCGCGCCCTGGCGGCGCGCGCA
GCGCCGCTGGTGGCGATCCTGTGGGGTCGTGACGCGTCGACTCTGAAGCCGATGCTGGCC
GCGGGCAACTGCGTTGCGATCGAGTCGCCGCATCCTTCACCGCTATCGGCATCGCGCGGG
TTCTTCGGCTCGCGTCCGTTCAGCCGCGCCAACGAACTGCTCGTCGGGATGGGTGCCGAG
CCGATCGATTGGCGGTTGCCCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Other	TBPWY:Base excision repair (BER)	active	vmizrahi	2012-03-05
Other	TBPWY:Base excision repair (BER)	active	vmizrahi	2012-03-05
	Required for survival during early stages of infection in mice (Sassetti & Rubin, 2003). Expression level increases with disease progression during chronic mouse infection (Talaat et al. 2007)