Rv2996c - D-3-phosphoglycerate dehydrogenase serA1

Expression: Most Significant Conditions for Rv2996c

Protein Domains

Gene Information
Locus	Rv2996c
Symbol	serA1
Gene Name	D-3-phosphoglycerate dehydrogenase serA1
Location	3353483 - 3355069 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1587 bp Protein:529 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	35225
Related Genes	Acel_0709 CE1379 cg1451 DIP1104 jk1291 MAP3033c MAV_3847 Mkms_1956 ML1692 Mmcs_1910 MSMEG_2378 MT3074 MUL_1952 Mvan_2128 nfa42210 SAV2730
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2996c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2996c Transcript 1
MSLPVVLIADKLAPSTVAALGDQVEVRWVDGPDRDKLLAAVPEADALLVRSATTVDAEVL
AAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAA
DASLREHTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAA
QLGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAA
LADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVR
LALAGEFVPDAVNVGGGVVNEEVAPWLDLVRKLGVLAGVLSDELPVSLSVQVRGELAAEE
VEVLRLSALRGLFSAVIEDAVTFVNAPALAAERGVTAEICKASESPNHRSVVDVRAVGAD
GSVVTVSGTLYGPQLSQKIVQINGRHFDLRAQGINLIIHYVDRPGALGKIGTLLGTAGVN
IQAAQLSEDAEGPGATILLRLDQDVPDDVRTAIAAAVDAYKLEVVDLS*

Genomic Sequence

>Rv2996c
GTGAGCCTGCCTGTTGTGTTGATCGCCGACAAACTTGCCCCATCAACGGTTGCCGCCTTG
GGAGATCAGGTCGAGGTGCGCTGGGTTGACGGTCCGGACCGAGACAAGCTGCTGGCCGCG
GTGCCCGAAGCGGACGCGCTGCTGGTGCGATCGGCCACCACGGTTGACGCCGAGGTGCTG
GCCGCCGCCCCCAAGCTCAAGATCGTCGCGCGCGCCGGCGTCGGGCTGGACAACGTCGAC
GTGGACGCCGCGACGGCCCGCGGCGTGCTGGTGGTCAACGCCCCGACGTCGAACATCCAC
AGCGCCGCGGAGCATGCGCTGGCGCTGCTGCTGGCCGCCTCACGCCAGATTCCGGCGGCC
GACGCGTCGCTGCGCGAGCACACCTGGAAGCGTTCGTCGTTTTCCGGTACCGAGATCTTC
GGCAAAACCGTCGGCGTGGTGGGTCTGGGCCGCATCGGGCAGTTGGTCGCCCAGCGGATC
GCTGCGTTCGGCGCTTACGTCGTCGCCTATGACCCGTACGTTTCGCCGGCCCGTGCGGCG
CAGCTGGGCATCGAACTGCTGTCCCTGGACGACCTGCTGGCCCGCGCCGATTTCATCTCG
GTGCACCTACCGAAAACACCGGAGACGGCGGGACTGATCGACAAGGAGGCGCTGGCGAAG
ACCAAGCCGGGCGTCATCATCGTCAACGCCGCGCGCGGCGGCCTGGTGGACGAGGCGGCA
CTGGCCGACGCGATCACCGGCGGCCACGTGCGGGCGGCCGGTCTGGACGTGTTCGCCACC
GAACCGTGCACCGACAGCCCGCTGTTCGAGCTGGCACAGGTGGTGGTCACACCGCATCTG
GGTGCGTCCACCGCGGAGGCGCAGGACCGGGCGGGCACCGACGTCGCCGAGAGCGTGCGG
CTGGCCCTGGCAGGGGAATTCGTGCCCGACGCGGTCAACGTCGGCGGCGGAGTGGTCAAC
GAGGAGGTGGCGCCCTGGCTGGATCTGGTGCGTAAGCTCGGCGTGCTGGCGGGTGTGTTG
TCCGACGAACTGCCGGTGTCGTTGTCGGTGCAGGTGCGCGGTGAGCTGGCCGCCGAAGAG
GTTGAGGTGCTGCGCCTTTCGGCGCTGCGCGGCCTGTTCTCGGCGGTGATCGAGGATGCG
GTGACATTTGTCAACGCACCGGCATTGGCCGCCGAACGTGGCGTCACCGCCGAGATCTGT
AAGGCCTCGGAAAGCCCCAACCACCGCAGCGTCGTCGACGTTCGCGCGGTCGGCGCGGAC
GGTTCGGTGGTGACCGTCTCGGGCACGCTGTATGGCCCACAGCTGTCGCAGAAGATCGTG
CAGATCAACGGCCGCCACTTTGATCTGCGCGCCCAGGGGATCAACCTGATCATCCACTAC
GTCGACCGGCCGGGAGCGCTGGGCAAGATCGGCACGTTGCTGGGGACGGCCGGGGTGAAT
ATCCAGGCCGCGCAGCTCTCCGAAGACGCCGAAGGCCCGGGCGCGACGATTCTGCTGCGG
CTGGACCAAGACGTGCCCGACGACGTGCGGACGGCGATCGCGGCGGCGGTGGACGCCTAC
AAGCTCGAGGTTGTCGATCTGTCGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006