Rv3010c - 6-phosphofructokinase pfkA

Expression: Most Significant Conditions for Rv3010c

Protein Domains

Gene Information
Locus	Rv3010c
Symbol	pfkA
Gene Name	6-phosphofructokinase pfkA
Location	3368823 - 3369854 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1032 bp Protein:344 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	29224
Related Genes	Acel_0983 CE1348 cg1409 DIP1088 jk1308 MAP3044c MAV_3858 Mkms_1938 ML1701 Mmcs_1892 MT3090 MUL_1940 Mvan_2116 nfa42410 PPA0090 SAV6083
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3010c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3010c Transcript 1
MRIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLLENRRVQLHNDDRNDR
LLAKGGTMLGTARVHPDKLRAGLPQIMQTLDDNGIDVLIPIGGEGTLTAASWLSEENVPV
VGVPKTIDNDIDCTDVTFGHDTALTVATEAIDRLHSTAESHERVMLVEVMGRHAGWIALN
AGLASGAHMTLIPEQPFDIEEVCRLVKGRFQRGDSHFICVVAEGAKPAPGTIMLREGGLD
EFGHERFTGVAAQLAVEVEKRINKDVRVTVLGHIQRGGTPTAYDRVLATRFGVNAADAAH
AGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAAFFG*

Genomic Sequence

>Rv3010c
ATGCGGATTGGAGTTCTTACCGGAGGCGGCGACTGTCCCGGCCTTAACGCCGTCATCCGT
GCGGTGGTGCGTACCTGCCACGCCCGATACGGCTCGTCGGTGGTCGGATTTCAGAACGGC
TTTCGCGGGCTGCTGGAGAACCGCCGTGTTCAACTGCACAACGACGACCGCAATGACCGG
CTGCTGGCCAAGGGCGGCACGATGCTGGGCACGGCCCGGGTGCACCCCGACAAACTGCGG
GCGGGGCTGCCCCAAATCATGCAGACCTTGGACGACAACGGGATCGACGTCCTGATCCCG
ATCGGCGGTGAGGGTACGCTGACCGCCGCGAGTTGGCTCTCCGAAGAGAATGTGCCGGTG
GTCGGGGTGCCAAAGACGATCGACAACGACATCGACTGCACCGATGTGACCTTCGGCCAC
GACACCGCGTTGACCGTGGCCACCGAGGCCATCGACCGGCTGCACAGCACCGCCGAATCC
CACGAGCGGGTGATGCTGGTGGAGGTGATGGGTAGGCATGCCGGCTGGATCGCGCTGAAC
GCCGGGCTGGCCTCCGGTGCTCACATGACCCTGATTCCTGAGCAGCCGTTCGACATCGAA
GAGGTGTGCCGACTGGTCAAAGGCCGTTTCCAGCGCGGGGACTCGCATTTCATCTGCGTG
GTCGCCGAAGGCGCCAAACCGGCTCCGGGGACGATCATGCTGCGCGAGGGTGGTCTCGAC
GAGTTCGGGCACGAGCGTTTCACAGGTGTAGCGGCGCAGCTGGCGGTCGAGGTCGAGAAG
CGCATCAACAAGGATGTCCGGGTGACGGTGTTGGGCCACATCCAGCGGGGTGGTACTCCG
ACCGCCTACGACCGAGTGCTGGCCACCCGATTCGGGGTGAACGCCGCCGACGCCGCGCAT
GCGGGCGAGTACGGCCAGATGGTGACGTTGCGCGGCCAGGACATCGGTCGGGTTCCGCTG
GCGGATGCGGTTCGCAAACTCAAACTGGTGCCGCAGAGCCGTTACGACGACGCCGCCGCC
TTCTTCGGTTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv2711	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002
Term	EC:2.7.1.11 6-phosphofructokinase. - NR	active	extern:JZUCKER	2012-03-06
	Traceable author statement to experimental support authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011