Rv3025c - cysteine desulfurase iscS

Expression: Most Significant Conditions for Rv3025c

Protein Domains

Gene Information
Locus	Rv3025c
Symbol	iscS
Gene Name	cysteine desulfurase iscS
Location	3383885 - 3385066 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1182 bp Protein:394 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	34174
Related Genes	Acel_0688 CE1330 cg1388 DIP1072 jk1321 MAP3058c MAV_3872 Mkms_1921 ML1708 Mmcs_1875 MSMEG_2357 MT3109 MUL_1927 Mvan_2105 nfa42680 PPA1116 SAV2756
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3025c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3025c Transcript 1
MAYLDHAATTPMHPAAIEAMAAVQRTIGNASSLHTSGRSARRRIEEARELIADKLGARPS
EVIFTAGGTESDNLAVKGIYWARRDAEPHRRRIVTTEVEHHAVLDSVNWLVEHEGAHVTW
LPTAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIAEMSVVAMEFGVPMHSDA
IQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALLLRRDVTCVPLMHGGGQERDIRSGT
PDVASAVGMATAAQIAVDGLEENSARLRLLRDRLVEGVLAEIDDVCLNGADDPMRLAGNA
HFTFRGCEGDALLMLLDANGIECSTGSACTAGVAQPSHVLIAMGVDAASARGSLRLSLGH
TSVEADVDAALEVLPGAVARARRAALAAAGASR*

Genomic Sequence

>Rv3025c
ATGGCCTACCTGGATCACGCTGCCACCACCCCGATGCACCCCGCCGCCATCGAGGCGATG
GCGGCCGTGCAGCGCACCATCGGCAATGCGTCGTCGCTGCACACCAGCGGGCGCTCGGCG
CGCCGGCGGATCGAGGAGGCCCGTGAGCTGATCGCGGACAAGCTAGGCGCTCGTCCGTCC
GAGGTGATCTTCACCGCGGGCGGCACCGAAAGCGACAACCTGGCTGTCAAAGGTATCTAT
TGGGCACGCCGCGATGCGGAGCCGCACCGCCGTCGCATCGTCACCACCGAGGTGGAACAC
CACGCCGTACTGGACTCGGTGAACTGGCTCGTGGAACACGAAGGCGCCCATGTGACCTGG
CTGCCGACCGCCGCCGACGGCTCGGTGTCGGCAACTGCGCTGCGCGAGGCACTGCAGAGC
CACGACGACGTCGCGCTGGTATCGGTGATGTGGGCCAACAACGAGGTCGGAACTATTCTA
CCGATCGCCGAAATGTCAGTTGTCGCCATGGAATTCGGCGTGCCGATGCACAGTGATGCC
ATTCAGGCGGTGGGACAGCTCCCGCTTGACTTCGGGGCCAGCGGGCTGTCGGCGATGAGC
GTGGCCGGGCACAAATTCGGTGGCCCGCCAGGAGTGGGTGCGTTGCTGCTGCGCCGCGAC
GTCACCTGCGTGCCCCTTATGCACGGCGGTGGGCAGGAGCGCGATATTCGTTCCGGCACA
CCCGATGTCGCCAGTGCAGTTGGAATGGCGACGGCCGCGCAGATCGCGGTGGACGGACTC
GAGGAAAACAGCGCGCGGTTACGGCTGCTGCGGGATCGTCTGGTCGAGGGTGTGCTGGCT
GAGATTGACGATGTTTGCCTTAACGGCGCCGATGACCCGATGCGGCTAGCGGGTAACGCG
CACTTCACTTTCCGTGGCTGCGAAGGCGATGCGCTGTTGATGTTGTTGGACGCTAACGGA
ATCGAGTGCTCAACCGGATCGGCCTGCACGGCAGGTGTAGCGCAGCCCTCGCATGTGTTG
ATTGCAATGGGCGTCGACGCGGCCAGCGCCCGCGGATCATTGCGTCTCTCGCTGGGGCAC
ACCAGTGTTGAGGCTGATGTCGATGCCGCGTTGGAGGTGCTTCCCGGGGCGGTGGCACGT
GCACGGCGGGCCGCCCTAGCCGCCGCGGGAGCATCCCGATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Activation Rv0868c	active	girishgene07	2012-10-05
	co-occurrence (functional linkage) authors,CT. Lauhon,R. Kambampati The iscS gene in Escherichia coli is required for the biosynthesis of 4-thiouridine, thiamin, and NAD. J. Biol. Chem. 2000
Interaction	Activation Rv0868c	active	girishgene07	2012-10-05
	co-occurrence (functional linkage) authors,K. Mieno [Digestive tract disease in the surgical department and acute abdomen]. Kango Gijutsu 1979
Interaction	Activation Rv0868c	active	girishgene07	2012-10-05
	co-occurrence (functional linkage) authors,W. Zhang,A. Urban,H. Mihara,S. Leimkühler,T. Kurihara,N. Esaki IscS functions as a primary sulfur-donating enzyme by interacting specifically with MoeB and MoaD in the biosynthesis of molybdopterin in Escherichia coli. J. Biol. Chem. 2010
Term	EC:2.8.1.7 Cysteine desulfurase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,B. Teusink,FH. van Enckevort,C. Francke,A. Wiersma,A. Wegkamp,EJ. Smid,RJ. Siezen In silico reconstruction of the metabolic pathways of Lactobacillus plantarum: comparing predictions of nutrient requirements with those from growth experiments. Appl. Environ. Microbiol. 2005