Rv3048c - ribonucleoside-diphosphate reductase beta chain nrdF2

Expression: Most Significant Conditions for Rv3048c

Protein Domains

Gene Information
Locus	Rv3048c
Symbol	nrdF2
Gene Name	ribonucleoside-diphosphate reductase beta chain nrdF2
Location	3408404 - 3409378 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:975 bp Protein:325 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33423
Related Genes	CE0879 MAP3095c MAV_3913 Mkms_1875 ML1731 Mmcs_1828 MSMEG_1033 MSMEG_2313 MT3133 MUL_1883 Mvan_2060 nfa42980
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3048c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3048c Transcript 1
MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQL
TMRVFTGLTMLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCST
AEIDDAFRWSEENRNLQRKAEIVLQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSR
AKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVE
YTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHD
FFSGSGSSYVIGKAVVTEDDDWDF*

Genomic Sequence

>Rv3048c
GTGACTGGAAACGCAAAGCTAATTGATCGAGTCTCAGCGATCAACTGGAACCGACTGCAA
GATGAGAAGGACGCCGAGGTCTGGGATCGGCTGACCGGAAACTTCTGGCTGCCCGAGAAG
GTGCCGGTGTCCAATGACATCCCGTCGTGGGGCACCCTGACCGCCGGCGAGAAGCAACTA
ACCATGCGGGTCTTCACCGGCCTGACCATGCTGGACACCATCCAGGGCACCGTTGGTGCG
GTCAGCCTGATTCCCGACGCGCTGACTCCGCATGAGGAGGCGGTGTTGACCAACATCGCG
TTTATGGAGTCGGTGCACGCCAAGAGCTACAGCCAGATCTTCTCCACGCTGTGTTCCACC
GCCGAGATCGACGACGCCTTCCGCTGGTCGGAGGAAAATCGCAATCTGCAGCGCAAGGCC
GAGATCGTGCTGCAGTACTACCGCGGCGACGAGCCGCTCAAGCGCAAGGTGGCCTCCACC
CTGCTGGAGAGCTTCCTGTTCTACTCTGGGTTCTACCTGCCGATGTACTGGTCGAGTCGG
GCCAAGTTGACCAACACCGCCGACATGATCCGGCTGATCATCCGCGACGAGGCCGTGCAC
GGTTACTACATCGGCTATAAGTTCCAGCGTGGTCTGGCGTTGGTTGACGACGTCACGCGC
GCCGAGCTCAAGGACTACACCTACGAGCTACTGTTCGAGCTCTACGACAACGAGGTGGAA
TACACCCAGGACCTCTACGACGAGGTCGGGCTAACCGAGGACGTCAAGAAGTTCTTGCGC
TACAACGCCAACAAGGCGCTGATGAACCTCGGCTATGAGGCGCTGTTCCCCCGCGATGAG
ACCGACGTGAACCCGGCCATCCTGTCGGCGCTGTCACCCAACGCCGACGAGAACCATGAC
TTCTTCTCCGGATCCGGGTCGAGCTATGTGATCGGCAAGGCGGTCGTCACCGAGGACGAT
GACTGGGACTTCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv3051c	active	kholia.trupti	2012-10-05
	SS. Dawes, DF. Warner et al. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infect. Immun. 2003
Interaction	RegulatedBy Rv0348	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
Term	EC:1.17.4.1 Ribonucleoside-diphosphate reductase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay SS. Dawes, DF. Warner et al. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infect. Immun. 2003