Rv3051c - ribonucleoside-diphosphate reductase alpha chain nrdE

Expression: Most Significant Conditions for Rv3051c

Protein Domains

Gene Information
Locus	Rv3051c
Symbol	nrdE
Gene Name	ribonucleoside-diphosphate reductase alpha chain nrdE
Location	3412085 - 3414166 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2082 bp Protein:694 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32764
Related Genes	Acel_1724 BL0670 CE2423 cg2786 DIP1867 jk0478 MAP3100c MAV_3919 Mkms_1864 ML1734 Mmcs_1817 MSMEG_1019 MSMEG_2299 MT3137 MUL_1878 Mvan_2042 nfa43070 PPA2121 SAV3026
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3051c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3051c Transcript 1
MLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYS
RNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGD
TALAELLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLS
KRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHA
HHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVP
FADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGK
ITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRA
LTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTV
LYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIP
TQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVY
YPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQI
YAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML*

Genomic Sequence

>Rv3051c
ATGCTGAACCTGTACGACGCGGACGGCAAGATCCAGTTCGACAAGGATCGGGAAGCAGCC
CACCAGTACTTTTTGCAGCATGTCAATCAGAACACGGTCTTCTTCCATAATCAGGACGAG
AAGCTCGACTACCTGATCCGCGAGAATTACTACGAGCGTGAGGTTCTCGACCAGTACTCG
CGCAACTTCGTCAAGACGCTGCTAGACCGCGCCTACGCCAAAAAGTTCCGGTTTCCGACG
TTTTTGGGTGCGTTCAAGTACTACACCTCCTACACGCTGAAAACCTTTGACGGGAAGCGC
TATCTGGAGCGCTTCGAGGACCGCGTGGTCATGGTGGCGCTAACGTTGGCCGCCGGCGAT
ACCGCACTTGCCGAGCTGCTGGTCGACGAGATCATCGACGGCCGCTTCCAGCCCGCCACA
CCGACGTTTTTGAATTCTGGCAAGAAGCAGCGCGGGGAGCCCGTGAGCTGTTTTTTGCTT
CGCGTCGAAGACAACATGGAGTCGATCGGACGGTCGATCAACTCCGCGCTGCAGCTATCC
AAGCGTGGCGGGGGAGTGGCGTTGCTGCTGACCAACATTCGCGAGCACGGCGCGCCGATC
AAGAACATCGAGAACCAGTCCTCGGGCGTCATCCCCATCATGAAGTTGCTGGAGGATGCG
TTCTCCTACGCCAACCAGCTGGGCGCTCGTCAAGGTGCCGGCGCGGTGTACCTGCACGCC
CATCACCCCGACATCTACCGATTCCTGGACACCAAGCGTGAGAACGCCGACGAGAAGATC
CGGATCAAGACGCTGAGTCTGGGGGTGGTGATCCCCGACATCACCTTCGAGTTGGCCAAG
CGCAACGATGACATGTACCTGTTCTCGCCCTACGATGTCGAGCGGGTCTACGGTGTGCCG
TTCGCTGACATCTCGGTCACCGAGAAGTACTACGAAATGGTCGATGACGCGCGCATCCGC
AAGACCAAGATCAAGGCACGGGAGTTCTTCCAGACGCTGGCCGAGCTGCAGTTCGAGTCC
GGCTACCCCTATATCATGTTCGAAGACACCGTCAATCGCGCTAATCCAATTGATGGCAAG
ATCACGCACAGCAACCTGTGCTCGGAGATCCTGCAAGTGTCTACGCCGTCATTGTTCAAC
GAGGACTTGTCGTATGCCAAAGTGGGCAAAGACATTTCGTGCAACCTGGGGTCGCTGAAC
ATCGCCAAGACGATGGACTCGCCGGACTTCGCGCAGACGATCGAGGTGGCGATCCGCGCG
TTGACCGCGGTGAGCGACCAAACCCATATCAAGTCGGTGCCCTCAATCGAGCAGGGCAAC
AACGACTCCCACGCGATCGGGCTAGGACAGATGAACCTGCACGGCTACCTGGCCCGGGAA
CGCATCTTCTACGGATCCGACGAAGGCATCGACTTCACCAACATCTACTTCTATACGGTG
CTGTATCACGCGTTGCGGGCATCCAACCGCATCGCGATCGAACGCGGCACGCACTTCAAG
GGTTTCGAGCGGTCCAAGTACGCGTCCGGGGAATTCTTCGACAAGTACACCGACCAGATT
TGGGAGCCGAAGACCCAGAAGGTACGCCAGCTGTTCGCCGACGCCGGCATCCGCATCCCA
ACGCAGGACGACTGGCGTCGGCTCAAGGAGTCGGTGCAAGCGCACGGCATCTACAACCAG
AACCTGCAGGCGGTGCCGCCGACCGGGTCGATTTCCTACATCAACCATTCGACGTCGTCG
ATTCACCCGATCGTGTCGAAGGTCGAGATCCGCAAGGAAGGCAAGATCGGGCGGGTCTAC
TACCCGGCGCCGTATATGACCAACGACAACCTGGAGTACTACGAAGACGCCTACGAGATC
GGTTACGAGAAGATCATCGACACCTACGCGGCGGCCACCCAGCATGTGGATCAAGGGCTT
TCGCTGACGTTGTTCTTCAAAGACACCGCCACCACCCGCGACGTGAACAAGGCGCAGATT
TACGCCTGGCGCAAGGGGATCAAGACGCTGTACTACATCCGGCTGCGGCAGATGGCGTTG
GAGGGCACCGAGGTCGAGGGTTGCGTGTCCTGCATGCTGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Signaling Rv3053c	active	harsharohiratruefriend	2012-10-05
	co-transcription WU. Leiting,XI. Jianping Comparative genomics analysis of Mycobacterium NrdH-redoxins. Microb. Pathog. null
Interaction	Signaling Rv3053c	active	harsharohiratruefriend	2012-10-05
	co-transcription authors,M. Stehr,G. Schneider,F. Aslund,A. Holmgren,Y. Lindqvist Structural basis for the thioredoxin-like activity profile of the glutaredoxin-like NrdH-redoxin from Escherichia coli. J. Biol. Chem. 2001
Interaction	Signaling Rv3053c	active	harsharohiratruefriend	2012-10-05
	co-transcription authors,E. Torrents,I. Roca,I. Gibert The open reading frame present in the nrdEF cluster of Corynebacterium ammoniagenes is a transcriptional regulator belonging to the GntR family. Curr. Microbiol. 2004
Interaction	PhysicalInteraction Rv3048c	active	kholia.trupti	2012-10-05
	SS. Dawes, DF. Warner et al. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infect. Immun. 2003
Term	EC:1.17.4.1 Ribonucleoside-diphosphate reductase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay SS. Dawes, DF. Warner et al. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infect. Immun. 2003