Rv3131 - conserved hypothetical protein

Expression: Most Significant Conditions for Rv3131

Protein Domains

Gene Information
Locus	Rv3131
Symbol
Gene Name	conserved hypothetical protein
Location	3496551 - 3497549 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:999 bp Protein:333 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	18951
Related Genes	MAP3273c MAV_4111 Mkms_2624 Mkms_4199 Mkms_4203 Mmcs_2579 Mmcs_4124 Mmcs_4128 MSMEG_5246 MT3212 MT3217 MUL_2417 MUL_2421 Mvan_0168 Mvan_2547 Mvan_2550 nfa27670 Rv3127
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3131
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3131 Transcript 1
MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRVCPTSLELFSRPDMQLRSTDPDGRELI
LSCGVALHHCVVALASLGWQAKVNRFPDPKDRCHLATIGVQPLVPDQADVALAAAIPRRR
TDRRAYSCWPVPGGDIALMAARAARGGVMLRQVSALDRMKAIVAQAVLDHVTDEEYLREL
TIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPADDGAAILALGTETD
DRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAKTRDAVRAEVFGAGGYPQMLLRVG
WAPINADPLPPTPRRELSQVVEWPEELLRQRC*

Genomic Sequence

>Rv3131
ATGAACACCCATTTCCCGGACGCCGAAACCGTGCGAACGGTTCTCACCCTGGCCGTCCGG
GCCCCCTCCATCCACAACACGCAGCCGTGGCGGTGGCGGGTATGCCCGACGAGTCTGGAG
CTGTTCTCTAGACCCGATATGCAGCTGCGTAGCACCGATCCGGACGGGCGTGAGTTGATC
CTCAGCTGTGGTGTGGCATTGCACCACTGCGTCGTCGCTTTGGCGTCGCTGGGCTGGCAG
GCCAAGGTAAACCGTTTCCCCGATCCCAAGGACCGCTGCCATCTGGCCACCATCGGGGTA
CAACCGCTTGTTCCCGATCAGGCCGATGTCGCCTTGGCGGCGGCCATACCGCGGCGACGC
ACCGATCGGCGCGCCTACAGTTGCTGGCCGGTGCCAGGAGGTGACATCGCGTTGATGGCC
GCAAGAGCAGCCCGTGGCGGGGTCATGCTGCGGCAGGTCAGTGCCCTAGACCGAATGAAA
GCCATTGTGGCGCAGGCTGTCTTGGACCACGTGACCGACGAGGAATATCTGCGCGAGCTC
ACCATTTGGAGTGGGCGCTACGGTTCAGTGGCCGGGGTTCCCGCCCGCAACGAGCCGCCA
TCAGACCCCAGTGCCCCGATCCCCGGTCGCCTGTTCGCCGGGCCCGGTCTGTCTCAGCCG
TCCGACGTCTTACCCGCTGACGACGGCGCCGCGATCCTGGCACTAGGCACCGAGACAGAC
GACCGGTTGGCCCGGCTGCGCGCCGGCGAGGCCGCCAGCATCGTCTTGTTGACCGCGACG
GCAATGGGGCTGGCGTGCTGCCCGATCACCGAACCGCTGGAGATCGCCAAGACCCGCGAC
GCGGTCCGTGCCGAGGTGTTCGGCGCCGGCGGCTACCCCCAGATGCTGCTGCGAGTGGGT
TGGGCACCGATCAATGCCGACCCGTTGCCACCGACGCCACGGCGCGAACTGTCCCAGGTC
GTTGAGTGGCCGGAAGAGCTACTGCGACAACGGTGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3133c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) S. Chauhan,JS. Tyagi Powerful induction of divergent tgs1-Rv3131 genes in Mycobacterium tuberculosis is mediated by DevR interaction with a high-affinity site and an adjacent cryptic low-affinity site. J. Bacteriol. 2009
Interaction	RegulatedBy Rv3911	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. S. Raman, X. Puyang et al. Mycobacterium tuberculosis SigM positively regulates Esx secreted protein and nonribosomal peptide synthetase genes and down regulates virulence-associated surface lipid synthesis. J. Bacteriol. 2006
Interaction	RegulatedBy Rv0348	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
Interaction	RegulatedBy Rv3133c	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008