Rv3224 - iron-regulated short-chain dehydrogenase/reductase

Expression: Most Significant Conditions for Rv3224

Protein Domains

Gene Information
Locus	Rv3224
Symbol
Gene Name	iron-regulated short-chain dehydrogenase/reductase
Location	3599851 - 3600699 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:849 bp Protein:283 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	13614
Related Genes	MAP3325 MAV_4172 Mkms_1383 Mmcs_1365 MSMEG_1894 MT3321 MUL_2546 Mvan_1776
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3224
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3224 Transcript 1
MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAG
GQALPIVGDIRDPDAVASAVATTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQ
VRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWLRPTAYMMAKYGMTLCALGIAEEM
RADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTL
LCEDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA*

Genomic Sequence

>Rv3224
ATGTCACTCAACGGCAAGACCATGTTCATCTCTGGCGCCAGTCGCGGTATCGGCCTTGCG
ATCGCCAAGCGGGCCGCGCGCGACGGCGCCAACATTGCCTTGATCGCCAAGACCGCCGAG
CCGCATCCAAAGCTGCCAGGCACGGTGTTCACGGCCGCCAAGGAACTCGAGGAAGCCGGC
GGCCAGGCACTGCCGATCGTCGGGGATATCCGCGACCCGGATGCGGTCGCGTCCGCGGTG
GCCACCACCGTGGAGCAGTTCGGGGGCATCGATATCTGCGTCAACAATGCCTCGGCGATC
AACTTAGGGTCCATCACCGAGGTGCCAATGAAGCGTTTCGACCTGATGAACGGCATCCAG
GTGCGTGGCACCTACGCAGTATCCCAAGCGTGCATTCCCCATATGAAAGGCCGTGAGAAC
CCGCACATCCTGACGCTGTCCCCGCCGATCCTGCTGGAGAAGAAGTGGCTGCGGCCGACG
GCCTACATGATGGCCAAGTACGGCATGACGCTGTGCGCGCTGGGAATCGCCGAGGAGATG
CGCGCCGACGGCATCGCGTCGAACACGTTGTGGCCACGCACGATGGTGGCCACCGCGGCG
GTACAGAACCTGCTGGGCGGCGACGAGGCGATGGCGCGGTCCCGCAAGCCCGAGGTATAC
GCCGACGCGGCCTACGTCATCGTCAACAAGCCCGCCACCGAATACACCGGCAAGACGCTG
CTGTGCGAGGACGTGCTCGTCGAATCCGGCGTCACCGACTTGTCGGTCTACGACTGCGTC
CCAGGTGCGACGCTCGGCGTCGACCTGTGGGTGGAAGACGCCAACCCGCCGGGGTACCTC
CCGGCCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001