Rv3240c - preprotein translocase secA1
Protein Domains

Gene Information
LocusRv3240c
SymbolsecA1
Gene Namepreprotein translocase secA1
Location3617682 - 3620531 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:2850 bp
Protein:950 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number32894
Related GenesAcel_1759 BL1419 CE0774 cg0868 DIP0699 jk1630 MAP3354c Mkms_1371 ML0779 Mmcs_1353 MSMEG_1881 MT3338 MUL_2576 Mvan_1762 nfa45990 PPA1333 SAV5071
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv3240c
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionPhysicalInteraction Rv1821activebhupender.srcp2012-10-05
Affinity purification(Physical Interaction)
JM. Hou, NG. D'Lima et al. ATPase activity of Mycobacterium tuberculosis SecA1 and SecA2 proteins and its importance for SecA2 function in macrophages. J. Bacteriol. 2008
InteractionPhysicalInteraction Rv1821activebhupender.srcp2012-10-05
Affinity purification(Physical Interaction)
M. Braunstein, AM. Brown et al. Two nonredundant SecA homologues function in mycobacteria. J. Bacteriol. 2001
InteractionPhysicalInteraction Rv1821activeatulkatarkar2012-10-05
Strucural analysis
M. Braunstein, BJ. Espinosa et al. SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis. Mol. Microbiol. 2003
InteractionPhysicalInteraction Rv1821activeatulkatarkar2012-10-05
Strucural analysis
M. Braunstein, AM. Brown et al. Two nonredundant SecA homologues function in mycobacteria. J. Bacteriol. 2001
InteractionPhysicalInteraction Rv1440activeshahanup862012-10-05

authors,F. Duong Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase. EMBO J. 2003
InteractionPhysicalInteraction Rv0732activeanshula.arora19902012-10-05
Structural analysis
JM. Hou, NG. D'Lima et al. ATPase activity of Mycobacterium tuberculosis SecA1 and SecA2 proteins and its importance for SecA2 function in macrophages. J. Bacteriol. 2008
InteractionPhysicalInteraction Rv0732activeanshula.arora19902012-10-05
Structural analysis
authors,C. Tziatzios,D. Schubert,M. Lotz,D. Gundogan,H. Betz,H. Schägger,W. Haase,F. Duong,I. Collinson The bacterial protein-translocation complex: SecYEG dimers associate with one or two SecA molecules. J. Mol. Biol. 2004