Rv3465 - dTDP-4-dehydrorhamnose 3,5-epimerase rmlC

Expression: Most Significant Conditions for Rv3465

Protein Domains

Gene Information
Locus	Rv3465
Symbol	rmlC
Gene Name	dTDP-4-dehydrorhamnose 3,5-epimerase rmlC
Location	3882834 - 3883442 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:609 bp Protein:203 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33275
Related Genes	BL0228 MAP4224c MAV_4407 Mkms_1081 ML1965 Mmcs_1065 MSMEG_1510 MT3571 MUL_0839 Mvan_1364 nfa2060
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3465
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3465 Transcript 1
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRG
LHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHG
FLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDV
RASGLLPRWEQTQRFIGEMRGT*

Genomic Sequence

>Rv3465
ATGAAAGCACGCGAACTCGACGTCCCCGGCGCCTGGGAGATTACCCCGACCATCCATGTC
GATTCCCGCGGACTGTTCTTCGAATGGCTTACCGATCATGGGTTCCGCGCATTCGCAGGT
CACAGTTTGGACGTCCGGCAAGTGAACTGCTCGGTGTCATCGGCCGGTGTGCTGCGCGGC
CTGCACTTTGCCCAGTTGCCGCCGAGCCAGGCCAAGTATGTGACCTGCGTTTCCGGCTCG
GTGTTCGATGTCGTCGTCGACATCCGAGAGGGCTCACCGACATTCGGCCGATGGGACTCG
GTGCTGCTCGACGACCAAGACCGTAGGACGATCTACGTCTCCGAAGGCCTAGCGCACGGC
TTCCTTGCACTGCAAGACAATTCGACGGTGATGTACTTGTGCTCGGCGGAATACAATCCG
CAGCGCGAGCACACCATCTGCGCCACAGATCCGACGTTGGCGGTCGATTGGCCGCTGGTC
GATGGCGCTGCCCCCAGCCTGTCCGACCGTGATGCCGCTGCGCCCAGCTTCGAGGATGTG
CGCGCGTCTGGCCTGCTGCCCAGGTGGGAACAGACGCAGCGGTTCATTGGGGAGATGCGC
GGCACCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	dTDP--D-xylo-4-keto-6-deoxy-hexulose epimerase: Formation of dTDP--L-lyxo-4-keto-6-deoxy-hexulose, the third step in dTDP-Rha synthesis	active	mjackson	2012-10-05
	dTDP-Rhamnose synthesis
Term	GO:0019305 dTDP-rhamnose biosynthetic process - NR	active	mmcneil	2012-03-05
	dTDP-Rha pathway: dTDP-D-xylo-4-keto-6-deoxy-hexulose epimerase: Formation of dTDP-β-L-lyxo-4-keto-6-deoxy-hexulose the third step in dTDP-Rha synthesis; enzymatic evidence authors,RJ. Stern,TY. Lee,TJ. Lee,W. Yan,MS. Scherman,VD. Vissa,SK. Kim,BL. Wanner,MR. McNeil Conversion of dTDP-4-keto-6-deoxyglucose to free dTDP-4-keto-rhamnose by the rmIC gene products of Escherichia coli and Mycobacterium tuberculosis. Microbiology (Reading, Engl.) 1999