Rv3541c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv3541c

Protein Domains

Gene Information
Locus	Rv3541c
Symbol
Gene Name	conserved hypothetical protein
Location	3980659 - 3981048 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:390 bp Protein:130 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	22837
Related Genes	MAP0526 MAV_0620 Mkms_4759 Mmcs_4673 MSMEG_5991 MT3645 MUL_4102 Mvan_5254 nfa4520
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3541c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3541c Transcript 1
MTVVGAVLPELKLYGDPTFIVSTALATRDFQDVHHDRDKAVAQGSKDIFVNILTDTGLVQ
RYVTDWAGPSALIKSIGLRLGVPWYAYDTVTFSGEVTAVNDGLITVKVVGRNTLGDHVTA
TVELSMRDS*

Genomic Sequence

>Rv3541c
ATGACGGTTGTTGGTGCTGTGCTGCCTGAGCTGAAGCTCTACGGAGACCCGACGTTCATC
GTCTCAACGGCGCTGGCTACCAGGGACTTCCAGGATGTGCATCATGATCGAGACAAGGCC
GTCGCCCAGGGGTCGAAAGACATTTTCGTCAACATCCTCACCGACACCGGGCTGGTGCAA
CGCTACGTCACCGACTGGGCGGGCCCGTCGGCGCTGATCAAGTCGATTGGGCTGCGGCTG
GGGGTGCCGTGGTACGCCTACGACACGGTGACGTTCTCCGGTGAGGTGACCGCGGTGAAC
GACGGCTTGATCACGGTAAAGGTGGTGGGCCGCAATACCCTTGGCGACCACGTGACCGCG
ACGGTGGAACTTTCGATGAGGGATTCGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	Regulatory Rv3574	active	ahal4789	2012-10-05
	Co-expression (Functional linkage) JC. Chang,MD. Miner,AK. Pandey,WP. Gill,NS. Harik,CM. Sassetti,DR. Sherman igr Genes and Mycobacterium tuberculosis cholesterol metabolism. J. Bacteriol. 2009
Interaction	Regulatory Rv3574	active	ahal4789	2012-10-05
	Co-expression (Functional linkage) SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
Interaction	Regulatory Rv3574	active	ahal4789	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	Regulatory Rv3574	active	ahal4789	2012-10-05
	Co-expression (Functional linkage) JC. Chang,MD. Miner,AK. Pandey,WP. Gill,NS. Harik,CM. Sassetti,DR. Sherman igr Genes and Mycobacterium tuberculosis cholesterol metabolism. J. Bacteriol. 2009
Interaction	Regulatory Rv3574	active	sourish10	2012-10-05
	Co-expression (Functional linkage) JC. Chang,MD. Miner,AK. Pandey,WP. Gill,NS. Harik,CM. Sassetti,DR. Sherman igr Genes and Mycobacterium tuberculosis cholesterol metabolism. J. Bacteriol. 2009
Interaction	Regulatory Rv3574	active	sourish10	2012-10-05
	Co-expression (Functional linkage) SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
Interaction	Regulatory Rv3574	active	sourish10	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	Regulatory Rv3574	active	sourish10	2012-10-05
	Co-expression (Functional linkage) JC. Chang,MD. Miner,AK. Pandey,WP. Gill,NS. Harik,CM. Sassetti,DR. Sherman igr Genes and Mycobacterium tuberculosis cholesterol metabolism. J. Bacteriol. 2009
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	M.smegmatis orthology based inference. Orthologous pair regulator-target found in M.smegmatis. SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Term	EC:4.2.1.- Lyases. Carbon-oxygen lyases. Hydro-lyases. - NR	active	nsampson	2012-03-05
	Assay of protein purified to homogeneity from a heterlogous host authors,ST. Thomas,BC. VanderVen,DR. Sherman,DG. Russell,NS. Sampson Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism. J. Biol. Chem. 2011
Other	product:3	active	rslayden	2012-03-05
	in preparation Thomas, Sampson
Term	EC:4.2.1.- Lyases. Carbon-oxygen lyases. Hydro-lyases. - NR	active	rslayden	2012-03-05
	in preparation Thomas, Sampson