Rv3571 - hemoglobine-related protein hmp

Expression: Most Significant Conditions for Rv3571

Protein Domains

Gene Information
Locus	Rv3571
Symbol	hmp
Gene Name	hemoglobine-related protein hmp
Location	4012417 - 4013493 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1077 bp Protein:359 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	27411
Related Genes	MAP0496c MAV_0590 Mkms_4796 Mmcs_4710 MSMEG_6039 MT3676 MUL_4142 Mvan_5309
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3571
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3571 Transcript 1
MTEAIGDEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPEIPPRRLRYAPGQFLTL
RVPSERTGSVARCYSLCSSPYTDDALAVTVKRTADGYASNWLCDHAQVGMRIHVLAPSGN
FVPTTLDADFLLLAAGSGITPIMSICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAA
KYPDRLTVLHWLESLQGLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQ
QVHIEVFKSLESDPFAAVKVDDSGDEAPATAVVELDGQTHTVSWPRTAKLLDVLLAAGLD
APFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEGLILACQSRPESDSVEVTYDE*

Genomic Sequence

>Rv3571
TTGACCGAGGCAATTGGAGACGAGCCACTCGGCGACCACGTCCTTGAACTGCAGATCGCC
GAGGTCGTCGACGAAACCGACGAGGCGCGATCGCTGGTCTTCGCGGTGCCCGACGGATCG
GACGACCCGGAGATCCCCCCTCGGCGCCTGCGTTACGCCCCCGGCCAATTCTTGACGCTG
CGCGTGCCCAGCGAGCGTACCGGTTCGGTGGCGCGCTGCTACTCGTTGTGCAGTTCGCCC
TACACCGACGACGCCTTGGCGGTCACGGTCAAACGAACCGCCGACGGGTACGCCTCCAAC
TGGTTGTGCGATCACGCGCAGGTGGGCATGCGCATCCACGTGCTGGCCCCGTCGGGCAAC
TTCGTCCCCACAACCCTCGACGCCGATTTCCTCCTGCTGGCAGCGGGTAGCGGCATCACC
CCGATCATGTCGATCTGCAAATCGGCGCTTGCCGAGGGCGGTGGACAGGTGACGCTGCTC
TACGCCAACCGCGACGACCGCTCGGTCATCTTCGGAGACGCGCTGCGCGAGTTGGCGGCG
AAGTATCCCGACCGGCTCACGGTGCTGCACTGGCTAGAGTCGCTGCAGGGGCTGCCGAGC
GCGAGCGCGCTGGCCAAGCTCGTCGCGCCCTACACCGACCGGCCGGTGTTCATCTGTGGG
CCCGGCCCGTTCATGCAGGCGGCCCGGGACGCCCTGGCGGCGCTGAAAGTGCCCGCCCAA
CAGGTGCACATCGAGGTGTTCAAGTCGCTGGAATCGGATCCGTTCGCGGCCGTCAAGGTC
GACGACAGCGGTGACGAGGCGCCGGCGACCGCGGTGGTGGAACTCGACGGCCAAACCCAC
ACCGTCTCCTGGCCGCGCACCGCCAAGCTGCTCGACGTGCTGCTGGCCGCGGGCCTGGAC
GCGCCGTTCTCCTGCCGGGAAGGCCACTGCGGTGCGTGTGCGTGCACCCTGCGCGCCGGC
AAAGTGAATATGGGAGTCAACGACGTGCTCGAGCAGCAGGATCTCGATGAGGGACTGATT
TTGGCCTGTCAATCTCGCCCGGAATCTGATTCGGTGGAAGTGACCTACGACGAGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Term	EC:1.14.13.- Oxidoreductases. Acting on paired donors, with incorporation or reduction of With NADH or NADPH as one donor, and incorporation of one atom - NR	active	nsampson	2012-03-05
	Assay of protein purified to homogeneity from a heterlogous host JK. Capyk,I. D'Angelo,NC. Strynadka,LD. Eltis Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis. J. Biol. Chem. 2009
Name	3-ketosteroid hydroxylase, reductase	active	cstolte	2011-01-03
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase)
Symbol	KshB	active	cstolte	2011-01-03
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase)
Name	3-ketosteroid hydroxylase, reductase	active	jgalag	2010-09-02
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase)
Symbol	KshB	active	jgalag	2010-09-02
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase)