Rv3710 - 2-isopropylmalate synthase leuA

Expression: Most Significant Conditions for Rv3710

Protein Domains

Gene Information
Locus	Rv3710
Symbol	leuA
Gene Name	2-isopropylmalate synthase leuA
Location	4153740 - 4155674 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1935 bp Protein:645 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32954
Related Genes	Acel_0794 BL0488 CE0216 cg0303 DIP0266 jk2002 MAP0312 MAV_0392 Mkms_4987 ML2324 Mmcs_4898 MSMEG_6271 MT3813 MUL_4300 Mvan_5515 nfa3080 PPA0941 SAV5601
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3710
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3710 Transcript 1
MTTSESPDAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRN
RTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQT
DFDFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVV
FRANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIA
PTPERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG
FAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPV
HERHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGR
TYEAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEM
WDAFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVH
ALADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPA
QPGEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVSAVNRAAR*

Genomic Sequence

>Rv3710
GTGACAACTTCTGAATCGCCCGACGCCTATACCGAGTCGTTTGGGGCCCACACCATCGTG
AAACCCGCCGGCCCACCTCGCGTCGGTCAGCCCTCGTGGAATCCGCAGCGAGCCTCGTCG
ATGCCGGTCAACCGCTACCGGCCGTTCGCCGAGGAGGTCGAGCCCATCCGGCTGAGAAAC
CGCACGTGGCCTGATCGCGTCATCGATCGTGCGCCGCTGTGGTGCGCGGTCGACTTACGC
GATGGCAACCAGGCGCTGATCGACCCGATGAGCCCGGCCCGCAAGCGCCGCATGTTCGAC
CTGCTGGTCCGGATGGGCTACAAGGAGATTGAGGTGGGGTTCCCCTCGGCCAGCCAGACC
GACTTCGACTTCGTCAGAGAGATCATCGAGCAGGGCGCCATTCCCGACGACGTCACCATC
CAGGTGCTCACCCAATGCCGTCCCGAGCTGATCGAGCGCACCTTCCAGGCGTGTTCGGGC
GCACCCCGGGCCATCGTGCACTTCTACAACTCGACGTCAATCCTGCAGCGCCGCGTGGTC
TTTCGCGCCAACCGGGCTGAGGTGCAGGCCATCGCGACAGATGGGGCGCGCAAGTGCGTC
GAGCAGGCCGCCAAATACCCGGGCACGCAGTGGCGATTCGAGTACTCCCCGGAGTCCTAC
ACCGGCACCGAACTGGAATACGCCAAACAGGTGTGCGACGCCGTCGGCGAGGTCATTGCG
CCGACGCCGGAGCGCCCGATCATCTTCAACCTGCCCGCCACGGTGGAGATGACGACGCCC
AATGTCTACGCCGACTCGATCGAGTGGATGAGCCGCAACCTAGCCAACCGGGAGTCGGTC
ATCCTGAGCCTGCACCCGCACAATGACCGCGGAACCGCCGTCGCCGCAGCGGAATTGGGT
TTCGCGGCCGGGGCTGATCGGATCGAGGGCTGCCTGTTCGGCAACGGCGAGCGCACCGGC
AACGTGTGCCTGGTCACGCTGGGACTCAACCTGTTCTCCCGAGGTGTGGACCCGCAGATC
GACTTCTCCAATATTGACGAGATCCGGCGCACGGTGGAGTACTGCAACCAGCTGCCGGTG
CACGAACGTCACCCCTATGGCGGCGACCTGGTGTACACCGCGTTCTCCGGTAGCCACCAG
GACGCCATCAACAAGGGCCTAGACGCGATGAAGCTGGATGCGGATGCCGCCGACTGTGAC
GTCGACGACATGCTGTGGCAGGTGCCGTATCTGCCCATCGACCCGCGCGATGTCGGGCGC
ACCTACGAGGCGGTGATCCGGGTCAACTCGCAGTCCGGCAAGGGCGGCGTGGCCTACATC
ATGAAGACCGACCACGGCCTTTCCCTGCCGCGGCGGCTGCAGATCGAGTTTTCCCAGGTA
ATCCAGAAGATCGCAGAGGGTACAGCAGGCGAGGGTGGCGAGGTCTCGCCCAAGGAGATG
TGGGATGCGTTCGCCGAGGAGTATCTGGCCCCGGTGCGGCCTTTGGAGCGGATAAGGCAA
CATGTGGACGCTGCCGACGACGACGGCGGCACGACCAGCATCACGGCGACCGTCAAGATC
AACGGCGTGGAGACCGAGATCAGCGGGTCCGGTAACGGTCCGTTGGCCGCGTTCGTCCAT
GCGCTGGCCGATGTCGGGTTTGACGTGGCCGTGCTGGACTACTACGAGCACGCGATGAGC
GCCGGCGACGACGCTCAGGCCGCCGCGTATGTGGAGGCCTCCGTGACGATCGCGAGCCCG
GCGCAGCCGGGCGAAGCGGGTCGGCACGCATCGGACCCCGTGACGATCGCGAGCCCGGCG
CAGCCGGGCGAAGCGGGTCGGCACGCATCGGACCCCGTGACGAGTAAGACGGTGTGGGGT
GTCGGTATCGCACCGTCAATCACCACCGCGTCGCTGCGCGCCGTGGTGTCGGCGGTCAAC
CGGGCGGCACGCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008