Rv3808c - bifunctional UDP-galactofuranosyl transferase glfT

Expression: Most Significant Conditions for Rv3808c

Protein Domains

Gene Information
Locus	Rv3808c
Symbol	glfT
Gene Name	bifunctional UDP-galactofuranosyl transferase glfT
Location	4270366 - 4272279 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1914 bp Protein:638 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32426
Related Genes	CE2714 cg3191 DIP2198 jk0130 MAP0212 MAV_0209 Mkms_5107 ML0093 Mmcs_5019 MSMEG_6403 MT3915 MUL_4992 Mvan_5649 nfa1770
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3808c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3808c Transcript 1
MSELAASLLSRVILPRPGEPLDVRKLYLEESTTNARRAHAPTRTSLQIGAESEVSFATYF
NAFPASYWRRWTTCKSVVLRVQVTGAGRVDVYRTKATGARIFVEGHDFTGTEDQPAAVET
EVVLQPFEDGGWVWFDITTDTAVTLHSGGWYATSPAPGTANIAVGIPTFNRPADCVNALR
ELTADPLVDQVIGAVIVPDQGERKVRDHPDFPAAAARLGSRLSIHDQPNLGGSGGYSRVM
YEALKNTDCQQILFMDDDIRLEPDSILRVLAMHRFAKAPMLVGGQMLNLQEPSHLHIMGE
VVDRSIFMWTAAPHAEYDHDFAEYPLNDNNSRSKLLHRRIDVDYNGWWTCMIPRQVAEEL
GQPLPLFIKWDDADYGLRAAEHGYPTVTLPGAAIWHMAWSDKDDAIDWQAYFHLRNRLVV
AAMHWDGPKAQVIGLVRSHLKATLKHLACLEYSTVAIQNKAIDDFLAGPEHIFSILESAL
PQVHRIRKSYPDAVVLPAASELPPPLHKNKAMKPPVNPLVIGYRLARGIMHNLTAANPQH
HRRPEFNVPTQDARWFLLCTVDGATVTTADGCGVVYRQRDRAKMFALLWQSLRRQRQLLK
RFEEMRRIYRDALPTLSSKQKWETALLPAANQEPEHG*

Genomic Sequence

>Rv3808c
ATGAGTGAACTCGCCGCGAGCCTGCTGTCTCGGGTCATCCTGCCGCGCCCAGGTGAACCC
CTTGACGTGCGCAAGCTGTACCTCGAGGAGTCAACGACCAACGCCCGGCGCGCGCATGCG
CCAACCCGGACCTCGCTACAGATTGGCGCGGAGTCCGAGGTGTCGTTCGCCACCTACTTC
AACGCTTTCCCGGCTAGCTATTGGCGACGTTGGACGACGTGCAAATCGGTGGTGTTGCGC
GTGCAGGTGACCGGCGCCGGGCGGGTAGACGTCTACCGGACCAAGGCCACCGGTGCCCGG
ATCTTCGTTGAGGGCCACGACTTCACCGGCACCGAGGATCAGCCAGCCGCCGTGGAGACC
GAAGTGGTGCTGCAGCCTTTCGAAGACGGCGGGTGGGTCTGGTTCGACATCACCACCGAC
ACCGCGGTCACCCTGCACAGTGGTGGCTGGTATGCCACCAGCCCCGCTCCGGGGACGGCC
AACATCGCGGTCGGCATCCCGACGTTCAACCGCCCCGCAGACTGCGTCAACGCGCTGCGA
GAACTCACCGCCGATCCGCTGGTGGACCAGGTGATCGGGGCGGTGATCGTGCCTGATCAG
GGTGAGCGCAAGGTGCGCGACCACCCGGATTTCCCCGCCGCGGCTGCGAGATTGGGTAGT
CGGCTCTCCATCCACGACCAGCCCAACCTGGGCGGTTCCGGCGGCTACAGCCGGGTGATG
TATGAGGCACTGAAAAACACCGACTGTCAGCAGATCCTATTCATGGACGACGACATCCGC
CTCGAGCCGGACTCGATTCTGCGGGTGCTGGCCATGCACCGGTTCGCCAAGGCGCCGATG
CTGGTGGGTGGTCAGATGCTCAACCTGCAGGAGCCGTCGCACCTGCACATCATGGGCGAA
GTCGTAGACCGGTCGATATTCATGTGGACCGCCGCGCCGCATGCCGAGTATGACCACGAC
TTCGCCGAATACCCGTTGAACGACAACAACTCCCGTAGCAAGTTGCTGCACCGGCGTATC
GATGTCGACTACAACGGCTGGTGGACGTGCATGATCCCACGCCAGGTCGCCGAAGAGCTA
GGACAGCCGCTGCCGTTGTTCATCAAATGGGACGACGCCGATTACGGCCTGCGGGCCGCC
GAGCACGGGTATCCGACCGTCACGCTGCCCGGTGCGGCGATCTGGCACATGGCCTGGAGC
GATAAGGATGACGCCATCGACTGGCAGGCCTATTTCCATCTGCGCAACCGGCTGGTGGTG
GCCGCCATGCACTGGGACGGCCCAAAGGCGCAAGTCATCGGCCTGGTCCGCAGCCATCTC
AAGGCAACCCTGAAACACCTTGCCTGCCTGGAATATTCGACGGTGGCAATCCAGAACAAG
GCCATCGACGACTTTCTCGCCGGCCCCGAGCACATCTTTTCGATCCTGGAATCGGCGCTG
CCGCAAGTGCACCGCATCCGCAAGAGCTATCCGGACGCGGTGGTGCTGCCGGCGGCCAGT
GAGTTGCCGCCGCCGTTGCACAAGAACAAGGCAATGAAGCCGCCGGTGAACCCGTTGGTC
ATCGGCTACCGGCTGGCCCGCGGGATCATGCACAACCTGACCGCCGCCAACCCCCAACAC
CACCGTCGCCCGGAGTTCAACGTTCCGACCCAGGATGCGCGCTGGTTCCTGCTGTGCACT
GTCGACGGGGCCACCGTCACCACGGCCGACGGATGCGGCGTGGTCTACCGGCAGCGCGAC
CGGGCCAAGATGTTCGCGTTGCTGTGGCAGTCGTTGCGCCGTCAGCGCCAGTTGCTGAAA
CGGTTCGAGGAGATGCGCCGGATTTATCGCGACGCGTTGCCGACGCTGTCCAGCAAGCAG
AAGTGGGAGACGGCGCTGCTGCCGGCGGCAAACCAAGAGCCCGAGCATGGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Term	TBRXN:GALFT galactofuranose transferse (M tb) - ISS	active	njamshidi	2012-10-05
	See PMID: 11555614, 11304545, 10934214 - total number of Galf added for Mtb believed to be between 30 and 50, added 30 for current model version as per Crick et al 2001 Glycobiology K. Mikusová, T. Yagi et al. Biosynthesis of the galactan component of the mycobacterial cell wall. J. Biol. Chem. 2000
Term	TBRXN:GALFT galactofuranose transferse (M tb) - ISS	active	njamshidi	2012-10-05
	See PMID: 11555614, 11304545, 10934214 - total number of Galf added for Mtb believed to be between 30 and 50, added 30 for current model version as per Crick et al 2001 Glycobiology L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Term	TBRXN:GALFT galactofuranose transferse (M tb) - ISS	active	njamshidi	2012-10-05
	See PMID: 11555614, 11304545, 10934214 - total number of Galf added for Mtb believed to be between 30 and 50, added 30 for current model version as per Crick et al 2001 Glycobiology authors,DC. Crick,S. Mahapatra,PJ. Brennan Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis. Glycobiology 2001
Term	TBRXN:GALFT galactofuranose transferse (M tb) - IDA	active	njamshidi	2012-10-05
	See PMID: 11555614, 11304545, 10934214 - total number of Galf added for Mtb believed to be between 30 and 50, added 30 for current model version as per Crick et al 2001 Glycobiology K. Mikusová, T. Yagi et al. Biosynthesis of the galactan component of the mycobacterial cell wall. J. Biol. Chem. 2000
Term	TBRXN:GALFT galactofuranose transferse (M tb) - IDA	active	njamshidi	2012-10-05
	See PMID: 11555614, 11304545, 10934214 - total number of Galf added for Mtb believed to be between 30 and 50, added 30 for current model version as per Crick et al 2001 Glycobiology L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Term	TBRXN:GALFT galactofuranose transferse (M tb) - IDA	active	njamshidi	2012-10-05
	See PMID: 11555614, 11304545, 10934214 - total number of Galf added for Mtb believed to be between 30 and 50, added 30 for current model version as per Crick et al 2001 Glycobiology authors,DC. Crick,S. Mahapatra,PJ. Brennan Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis. Glycobiology 2001
Name	Bifucntional galactofuranosyl transferase which elongate the galactan of approximately 24 residues from Gal-Gal-Rha-GlcNAc-P-P-decaprenyl carrier lipid	active	mjackson	2012-10-05
	Galactosyltransferases
Symbol	glfT2	active	mjackson	2012-10-05
	Galactosyltransferases
Term	EC:2.-.-.- Transferases. - NR	active	extern:JZUCKER	2012-03-06
	Inferred from direct assay authors,DC. Crick,S. Mahapatra,PJ. Brennan Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis. Glycobiology 2001
Term	EC:2.4.1.205 Galactogen 6-beta-galactosyltransferase. - NR	active	extern:JZUCKER	2012-03-06
	Inferred from direct assay authors,DC. Crick,S. Mahapatra,PJ. Brennan Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis. Glycobiology 2001
Term	EC:2.4.1.- Transferases. Glycosyltransferases. Hexosyltransferases. - NR	active	extern:JZUCKER	2012-03-06
	Inferred from direct assay authors,DC. Crick,S. Mahapatra,PJ. Brennan Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis. Glycobiology 2001
Term	EC:2.-.-.- Transferases. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein purified to homogeneity from a heterlogous host L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Term	EC:2.4.1.205 Galactogen 6-beta-galactosyltransferase. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein purified to homogeneity from a heterlogous host L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Term	EC:2.4.1.- Transferases. Glycosyltransferases. Hexosyltransferases. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein purified to homogeneity from a heterlogous host L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Term	EC:2.4.1.- Transferases. Glycosyltransferases. Hexosyltransferases. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein partially-purified from a heterlogous host L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Term	GO:0008378 galactosyltransferase activity - NR	active	mmcneil	2012-03-05
	Bifunctional Galactofuranosyl transferase which elongate the galactan of approximately 24 residues from Gal-Gal-Rha-GlcNAc-P-P-decaprenyl carrier lipid F. Pan, M. Jackson et al. Cell wall core galactofuran synthesis is essential for growth of mycobacteria. J. Bacteriol. 2001
Symbol	glfT2	active	mmcneil	2012-03-05
	Bifunctional Galactofuranosyl transferase which elongate the galactan of approximately 24 residues from Gal-Gal-Rha-GlcNAc-P-P-decaprenyl carrier lipid F. Pan, M. Jackson et al. Cell wall core galactofuran synthesis is essential for growth of mycobacteria. J. Bacteriol. 2001
Term	GO:0008378 galactosyltransferase activity - NR	active	mmcneil	2012-03-05
	Bifunctional Galactofuranosyl transferase which elongate the galactan of approximately 24 residues from Gal-Gal-Rha-GlcNAc-P-P-decaprenyl carrier lipid L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Symbol	glfT2	active	mmcneil	2012-03-05
	Bifunctional Galactofuranosyl transferase which elongate the galactan of approximately 24 residues from Gal-Gal-Rha-GlcNAc-P-P-decaprenyl carrier lipid L. Kremer, LG. Dover et al. Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J. Biol. Chem. 2001
Term	EC:2.-.-.- Transferases. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,DC. Crick,S. Mahapatra,PJ. Brennan Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis. Glycobiology 2001