Rv3843c - conserved membrane protein

Expression: Most Significant Conditions for Rv3843c

Protein Domains

Gene Information
Locus	Rv3843c
Symbol
Gene Name	conserved membrane protein
Location	4315568 - 4316596 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1029 bp Protein:343 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	3453
Related Genes	MAP0189 MAV_0184 Mkms_5129 ML0073 Mmcs_5041 MSMEG_6424 MT3951 MUL_5016 Mvan_5668 nfa1240
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3843c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3843c Transcript 1
MIQVCSQCGTGWNVRERQRVWCPRCRGMLLAPLADMPAEARWRTPARPQVPTASDTRRTP
PRLPPGFRWIAVRPGAAPPPRHGPRLRGPTPRYAGIPRWGLTDHVDQAPVPASAKAGPSP
AAVRTTLLVSLLVFSIAVVVFVVRYVLLVINRNTLLNSVVASASVWLGVLVSLAAIAAAG
TTIVLLVRWLVARRAAAFMHQGLPERRSARELWAGCLLPMVNLLWAPLYVIELALVEDRY
TRLRRPIVVWWIVWIVSNAISMFAFATSWVTDAQGIANNTTMMVLAYLCAAAAVAAAARV
FEGFEQKPVERPAHRWVVVNTDGRSAPASSVAVELDGQEPAA*

Genomic Sequence

>Rv3843c
GTGATCCAAGTGTGCTCCCAGTGCGGAACTGGCTGGAACGTCCGTGAGCGGCAACGCGTG
TGGTGTCCACGCTGTCGGGGGATGTTGCTGGCGCCGTTGGCGGATATGCCGGCCGAGGCG
CGCTGGCGTACACCGGCGCGCCCGCAGGTGCCGACGGCCTCCGACACGCGGCGCACACCG
CCGCGGCTTCCCCCAGGTTTTCGGTGGATAGCGGTGCGACCCGGGGCGGCACCGCCGCCA
CGGCACGGCCCACGGTTACGTGGGCCTACTCCCCGCTACGCCGGGATACCGCGGTGGGGG
CTAACCGACCATGTCGACCAGGCTCCCGTGCCGGCCTCGGCGAAAGCAGGGCCATCGCCG
GCGGCGGTGCGCACCACGCTGTTGGTGAGCCTGCTGGTGTTCAGCATCGCGGTCGTGGTG
TTTGTGGTGCGGTATGTGTTGCTGGTCATCAACCGAAACACATTGTTGAACTCGGTGGTG
GCCAGCGCCTCGGTCTGGCTGGGGGTTTTGGTCAGCTTGGCGGCGATTGCGGCGGCCGGC
ACTACCATTGTCCTGTTGGTCCGGTGGCTGGTCGCCCGTCGGGCCGCCGCGTTTATGCAT
CAAGGCTTGCCGGAGCGGCGTTCCGCCCGTGAGTTATGGGCCGGCTGCCTATTGCCGATG
GTCAATCTGCTGTGGGCTCCGCTGTACGTCATCGAGTTGGCGCTGGTCGAGGACCGCTAC
ACGCGGCTGCGCAGGCCGATCGTGGTGTGGTGGATCGTGTGGATCGTCAGCAACGCGATA
TCGATGTTCGCGTTCGCCACCAGCTGGGTCACCGACGCTCAGGGCATCGCCAACAACACC
ACCATGATGGTGCTGGCGTATCTGTGTGCGGCGGCCGCGGTGGCCGCTGCTGCGCGGGTC
TTCGAGGGGTTCGAGCAAAAGCCGGTCGAACGCCCAGCGCATCGCTGGGTGGTGGTGAAC
ACAGACGGGCGTTCCGCGCCGGCATCTTCTGTTGCGGTTGAGTTGGACGGGCAGGAACCG
GCAGCATAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
Interaction	Transcription Rv3676	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv2069	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008